4-氯乙酰乙酸乙酯

货号 (SKU)	包装规格	是否现货
E156137-25g	25g	现货
E156137-50g	50g	现货
E156137-100g	100g	现货
E156137-250g	250g	现货
E156137-500g	500g	现货
E156137-1kg	1kg	现货
E156137-2.5kg	2.5kg	现货

基本描述

别名	4-氯乙酰乙酯
英文别名	BCP24055 \| 4-CHLORO ACETOETHYLACETATE \| DTXCID2024454 \| Ethyl-4-chloroacetoacetate \| ethyl4-chloroacetoacetate \| EINECS 211-317-0 \| ETHYL .OMEGA.-CHLOROACETOACETATE \| ETHYL 3-OXO-4-CHLOROBUTANOATE \| ethyl-4-chloro-3-ketobutyrate \| Ethyl Chloroacetoacetate
规格或纯度	>95.0%(GC)
英文名称	Ethyl 4-Chloroacetoacetate
应用	4-氯乙酰乙酸乙酯用于合成磷叶立德。
储存温度	充氩
运输条件	常规运输
产品介绍	4-氯乙酰乙酸乙酯用于合成磷叶立德。 Ethyl 4-chloroacetoacetate was used in the synthesis of phosphorus ylides

名称和标识符

PubChem SID	488184334
EC号	211-317-0
IUPAC Name	ethyl 4-chloro-3-oxobutanoate
INCHI	InChI=1S/C6H9ClO3/c1-2-10-6(9)3-5(8)4-7/h2-4H2,1H3
InChi Key	OHLRLMWUFVDREV-UHFFFAOYSA-N
Canonical SMILES	CCOC(=O)CC(=O)CCl
Isomeric SMILES	CCOC(=O)CC(=O)CCl
WGK Germany	3
RTECS	AK5110000
PubChem CID	69484
分子量	164.59
Reaxy-Rn	1761275

数据库链接

PubChem SID	488184334

化学和物理性质

溶解性	Miscible with water and most organic solvents.
密度	1.212
敏感性	对空气敏感
折光率	1.452
闪点(℉)	198°F
闪点(℃)	92℃
沸点	220℃
熔点	-8℃

安全和危险性（GHS）

象形图	Toxic Environmental Hazard Corrosive Harmful
信号词	Danger
危险声明	H301: Toxic if swallowed H311: Toxic in contact with skin H411: Toxic to aquatic life with long lasting effects H314: Causes severe skin burns and eye damage H317: May cause an allergic skin reaction H310: Fatal in contact with skin
预防措施声明	P261,P273,P280,P302+P352,P321,P405,P501,P264,P260,P270,P301+P330+P331,P304+P340,P363,P272,P333+P313,P362+P364,P391,P330,P262,P361+P364,P301+P316,P305+P354+P338,P302+P361+P354,P316
WGK Germany	3
RTECS	AK5110000
Reaxy-Rn	1761275
个人防护装备	Faceshields， full-face respirator (US)， Gloves， Goggles， multi-purpose combination respirator cartridge (US)， type ABEK (EN14387) respirator filter

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参考文献

1. K Kita,T Fukura,K I Nakase,K Okamoto,H Yanase,M Kataoka,S Shimizu. (1999-12-03) Cloning, overexpression, and mutagenesis of the Sporobolomyces salmonicolor AKU4429 gene encoding a new aldehyde reductase, which catalyzes the stereoselective reduction of ethyl 4-chloro-3-oxobutanoate to ethyl (S)-4-chloro-3-hydroxybutanoate.. Applied and environmental microbiology, 65 ((12)): (5207-5211). [PMID:10583966]
2. Y Yasohara,N Kizaki,J Hasegawa,M Wada,M Kataoka,S Shimizu. (2000-08-17) Molecular cloning and overexpression of the gene encoding an NADPH-dependent carbonyl reductase from Candida magnoliae, involved in stereoselective reduction of ethyl 4-chloro-3-oxobutanoate.. Bioscience, biotechnology, and biochemistry, 64 ((7)): (1430-1436). [PMID:10945260]
3. Y Saratani,E Uheda,H Yamamoto,A Nishimura,F Yoshizako. (2001-08-23) Stereoselective reduction of ethyl 4-chloro-3-oxobutanoate by fungi.. Bioscience, biotechnology, and biochemistry, 65 ((7)): (1676-1679). [PMID:11515558]
4. Yuri Saratani,Eiji Uheda,Hiroaki Yamamoto,Atsuo Nishimura,Fumiki Yoshizako. (2003-07-05) Purification and properties of a carbonyl reductase involved in stereoselective reduction of ethyl 4-chloro-3-oxobutanoate from Cylindrocarpon sclerotigenum IFO 31855.. Bioscience, biotechnology, and biochemistry, 67 ((6)): (1417-1420). [PMID:12843676]
5. Hirokazu Nanba,Yasuko Takaoka,Junzo Hasegawa. (2003-10-31) Purification and characterization of an alpha-haloketone-resistant formate dehydrogenase from Thiobacillus sp. strain KNK65MA, and cloning of the gene.. Bioscience, biotechnology, and biochemistry, 67 ((10)): (2145-2153). [PMID:14586102]
6. Gerhard Jörg,Martin Bertau. (2003-12-26) Fungal aerobic reductive dechlorination of ethyl 2-chloroacetoacetate by Saccharomyces cerevisiae: mechanism of a novel type of microbial dehalogenation.. Chembiochem : a European journal of chemical biology, 5 ((1)): (87-92). [PMID:14695517]
7. H Yamamoto,K Mitsuhashi,N Kimoto,Y Kobayashi,N Esaki. (2004-09-01) Robust NADH-regenerator: improved alpha-haloketone-resistant formate dehydrogenase.. Applied microbiology and biotechnology, 67 ((1)): (33-39). [PMID:15338080]
8. Ying Liu,Zhinan Xu,Keju Jing,Xiaoxia Jiang,Jianping Lin,Fang Wang,Peilin Cen. (2005-02-11) Asymmetric reduction of ethyl 4-chloro-3-oxobutanoate to ethyl (R)-4-chloro-3-hydroxybutanoate with two co-existing, recombinant Escherichia coli strains.. Biotechnology letters, 27 ((2)): (119-125). [PMID:15703875]
9. Keju Jing,Zhinan Xu,Ying Liu,Xiaoxia Jiang,Li Peng,Peilin Cen. (2005-08-20) Efficient production of recombinant aldehyde reductase and its application for asymmetric reduction of ethyl 4-chloro-3-oxobutanoate to ethyl (R)-4-chloro-3-hydroxybutanoate.. Preparative biochemistry & biotechnology, 35 ((3)): (203-215). [PMID:16109633]
10. I Pieper,K Wechler,M Katzberg,L Brusch,P G Sørensen,F Mensonides,M Bertau. (2008-12-02) Biosimulation of drug metabolism--a yeast based model.. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 36 ((1)): (157-170). [PMID:19041718]
11. Hyun Joo Park,Jihye Jung,Hyejeong Choi,Ki-Nam Uhm,Hyung Kwoun Kim. (2010-10-05) Enantioselective bioconversion using Escherichia coli cells expressing Saccharomyces cerevisiae reductase and Bacillus subtilis glucose dehydrogenase.. Journal of microbiology and biotechnology, 20 ((9)): (1300-1306). [PMID:20890095]
12. Hou Cao,Lan Mi,Qi Ye,Guanglou Zang,Ming Yan,Yan Wang,Yueyuan Zhang,Ximu Li,Lin Xu,Jian Xiong,Pingkai Ouyang,Hanjie Ying. (2010-10-12) Purification and characterization of a novel NADH-dependent carbonyl reductase from Pichia stipitis involved in biosynthesis of optically pure ethyl (S)-4-chloro-3-hydroxybutanoate.. Bioresource technology, 102 ((2)): (1733-1739). [PMID:20933386]
13. Li-Juan Wang,Chun-Xiu Li,Yan Ni,Jie Zhang,Xiang Liu,Jian-He Xu. (2011-05-17) Highly efficient synthesis of chiral alcohols with a novel NADH-dependent reductase from Streptomyces coelicolor.. Bioresource technology, 102 ((14)): (7023-7028). [PMID:21570826]
14. Faramarz Rostami-Charati,Zinatossadat Hossaini,Majid Moradian,Ali Jafari,Abodolreza Yazdani. (2012-01-24) Microwave-assisted synthesis of cyclopentanones using the relevant phosphorus ylides.. Combinatorial chemistry & high throughput screening, 15 ((4)): (354-357). [PMID:22263857]
15. Mingdong An,Ping Cai,Ming Yan,Ning Hao,Shanshan Wang,Huan Liu,Yan Li,Lin Xu. (2012-07-14) A novel reductase from Candida albicans for the production of ethyl (S)-4-chloro-3-hydroxybutanoate.. Bioscience, biotechnology, and biochemistry, 76 ((6)): (1210-1212). [PMID:22790948]
16. Ping Cai,Mingdong An,Lin Xu,Sheng Xu,Ning Hao,Yan Li,Kai Guo,Ming Yan. (2012-08-25) Development of a substrate-coupled biocatalytic process driven by an NADPH-dependent sorbose reductase from Candida albicans for the asymmetric reduction of ethyl 4-chloro-3-oxobutanoate.. Biotechnology letters, 34 ((12)): (2223-2227). [PMID:22918792]
17. M Kataoka,K Yamamoto,H Kawabata,M Wada,K Kita,H Yanase,S Shimizu. (1999-05-26) Stereoselective reduction of ethyl 4-chloro-3-oxobutanoate by Escherichia coli transformant cells coexpressing the aldehyde reductase and glucose dehydrogenase genes.. Applied microbiology and biotechnology, 51 ((4)): (486-490). [PMID:10341431]
18. N Kizaki,Y Yasohara,J Hasegawa,M Wada,M Kataoka,S Shimizu. (2001-06-21) Synthesis of optically pure ethyl (S)-4-chloro-3-hydroxybutanoate by Escherichia coli transformant cells coexpressing the carbonyl reductase and glucose dehydrogenase genes.. Applied microbiology and biotechnology, 55 ((5)): (590-595). [PMID:11414326]
19. Jer-Yiing Houng,Jia-Sheng Liau. (2003-07-29) Applying slow-release biocatalysis to the asymmetric reduction of ethyl 4-chloroacetoacetate.. Biotechnology letters, 25 ((1)): (17-21). [PMID:12882300]
20. Hiroaki Yamamoto,Kazuya Mitsuhashi,Norihiro Kimoto,Akinobu Matsuyama,Nobuyoshi Esaki,Yoshinori Kobayashi. (2004-04-02) A novel NADH-dependent carbonyl reductase from Kluyveromyces aestuarii and comparison of NADH-regeneration system for the synthesis of ethyl (S)-4-chloro-3-hydroxybutanoate.. Bioscience, biotechnology, and biochemistry, 68 ((3)): (638-649). [PMID:15056898]
21. Zhinan Xu,Ying Liu,Limei Fang,Xiaoxia Jiang,Keju Jing,Peilin Cen. (2005-09-22) Construction of a two-strain system for asymmetric reduction of ethyl 4-chloro-3-oxobutanoate to (S)-4-chloro-3-hydroxybutanoate ethyl ester.. Applied microbiology and biotechnology, 70 ((1)): (40-46). [PMID:16175366]
22. Qi Ye,Ming Yan,Lin Xu,Hou Cao,Zhenjiang Li,Yong Chen,Shuya Li,Hanjie Ying. (2009-01-07) A novel carbonyl reductase from Pichia stipitis for the production of ethyl (S)-4-chloro-3-hydroxybutanoate.. Biotechnology letters, 31 ((4)): (537-542). [PMID:19125224]
23. Tarjan Kaliaperumal,S Kumar,Sathyanarayana N Gummadi,Anju Chadha. (2009-11-10) Asymmetric synthesis of (S)-ethyl-4-chloro-3-hydroxybutanoate using Candida parapsilosis ATCC 7330.. Journal of industrial microbiology & biotechnology, 37 ((2)): (159-165). [PMID:19898846]
24. Qi Ye,Ximu Li,Ming Yan,Hou Cao,Lin Xu,Yueyuan Zhang,Yong Chen,Jian Xiong,Pingkai Ouyang,Hanjie Ying. (2010-03-24) High-level production of heterologous proteins using untreated cane molasses and corn steep liquor in Escherichia coli medium.. Applied microbiology and biotechnology, 87 ((2)): (517-525). [PMID:20309539]
25. Chenxi Ning,Erzheng Su,Dongzhi Wei. (2014-12-03) Characterization and identification of three novel aldo-keto reductases from Lodderomyces elongisporus for reducing ethyl 4-chloroacetoacetate.. Archives of biochemistry and biophysics, 564 (): (219-228). [PMID:25447817]

4-氯乙酰乙酸乙酯

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库存信息

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基本描述

名称和标识符

数据库链接

化学和物理性质

安全和危险性（GHS）

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