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| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| G329630-1mg |
1mg |
现货  |
|
| 英文别名 | GM3 Na |
|---|---|
| 规格或纯度 | >98% |
| 英文名称 | Ganglioside GM3 sodium salt |
| 储存温度 | -20°C储存,充氩 |
| 运输条件 | 超低温冰袋运输 |
| 产品介绍 |
神经节苷脂GM3钠盐是神经外系统中主要的神经节苷脂。抑制表皮细胞的生长。GM3被称为主要的神经外神经节苷脂。神经节苷脂GM3钠盐可用作唾液酸酶的底物，在该处理后产生相应的乳糖基神经酰胺。也称为细胞生长因子（EGF和FGF）的共同受体。GM3抗体抑制3T3和NIL细胞生长。 Ganglioside GM3 sodium salt is the major ganglioside of the extra-nervous system. Inhibits growth of epidermal cells. GM3 is known as the main extraneuronal ganglioside. Ganglioside GM3 sodium salt is useful as a substrate for sialidase, after this treatment yields the corresponding lactosylceramide. Also known as the co-receptor of cell growth factor (EGF and FGF). Antibodies to GM3 inhibit 3T3 and NIL cell growth. product description： Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis and metastasis. The accumulation of gangliosides has been linked to several diseases. Ganglioside GM3 is the most abundant ganglioside in mammals. It is involved in several tumor processes by interacting with receptors. It inhibits epidermal cell growth and blocks insulin receptor activity. Exogenous GM3 ganglioside inhibits atherosclerosis. |
| IUPAC Name | sodium;(2S,4S,5R,6R)-5-acetamido-2-[(2S,3R,4S,5S,6R)-2-[(2R,3S,4R,5R,6R)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(E,2S,3R)-3-hydroxy-2-(octadecanoylamino)octadec-4-enoxy]oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylate |
|---|---|
| INCHI | InChI=1S/C59H108N2O21.Na/c1-4-6-8-10-12-14-16-18-19-21-23-25-27-29-31-33-46(69)61-40(41(66)32-30-28-26-24-22-20-17-15-13-11-9-7-5-2)38-77-56-51(73)50(72)53(45(37-64)79-56)80-57-52(74)55(49(71)44(36-63)78-57)82-59(58(75)76)34-42(67)47(60-39(3)65)54(81-59)48(70)43(68)35-62;/h30,32,40-45,47-57,62-64,66-68,70-74H,4-29,31,33-38H2,1-3H3,(H,60,65)(H,61,69)(H,75,76);/q;+1/p-1/b32-30+;/t40-,41+,42-,43+,44+,45+,47+,48+,49-,50+,51+,52+,53+,54+,55-,56+,57-,59-;/m0./s1 |
| InChi Key | GGQRTSSCXQEZNW-BLVJLEROSA-M |
| Canonical SMILES | CCCCCCCCCCCCCCCCCC(=O)NC(COC1C(C(C(C(O1)CO)OC2C(C(C(C(O2)CO)O)OC3(CC(C(C(O3)C(C(CO)O)O)NC(=O)C)O)C(=O)[O-])O)O)O)C(C=CCCCCCCCCCCCCC)O.[Na+] |
| Isomeric SMILES | CCCCCCCCCCCCCCCCCC(=O)N[C@@H](CO[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O[C@H]2[C@@H]([C@H]([C@H]([C@H](O2)CO)O)O[C@@]3(C[C@@H]([C@H]([C@@H](O3)[C@@H]([C@@H](CO)O)O)NC(=O)C)O)C(=O)[O-])O)O)O)[C@@H](/C=C/CCCCCCCCCCCCC)O.[Na+] |
| WGK Germany | 3 |
| PubChem CID | 71527022 |
| 分子量 | 1203.47 |
| 溶解性 | Soluble in water (partly), and chloroform:methanol (2:1).Soluble in water (liposomal aggregates) or chloroform:methanol (2:1) |
|---|---|
| 敏感性 | 对湿度敏感 |
| WGK Germany | 3 |
|---|---|
| 个人防护装备 | Eyeshields， Gloves， type N95 (US)， type P1 (EN143) respirator filter |
| RIDADR | NONHforallmodesoftransport |
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