DL-高胱氨酸

  • ≥98%
有货

库存信息

关闭
货号 (SKU) 包装规格 是否现货 价格 数量
H108029-5g
5g 现货 Stock Image

基本描述

别名 DL-同型胱氨酸
英文别名 Butyric acid, 4,4'-dithiobis(2-amino- | DS-9173 | C8H16N2O4S2 | NSC 226570 | SY112616 | SCHEMBL224295 | SY026490 | C20788 | EN300-52797 | HOMOCYSTINE | 3C9F56DF-A143-4F06-81E2-50796E255EEB | 4,4'-disulfanediylbis(2-ammoniobutanoate) | ZTVZLYBCZNMWCF-UHFFF
规格或纯度 ≥98%
英文名称 DL-Homocystine
运输条件 常规运输

AI解读

关联靶点(其它种属)

Rattus norvegicus (775804 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

名称和识别符

EC号 212-803-5
分子类型 小分子
IUPAC Name 2-amino-4-[(3-amino-3-carboxypropyl)disulfanyl]butanoic acid
INCHI InChI=1S/C8H16N2O4S2/c9-5(7(11)12)1-3-15-16-4-2-6(10)8(13)14/h5-6H,1-4,9-10H2,(H,11,12)(H,13,14)
InChi Key ZTVZLYBCZNMWCF-UHFFFAOYSA-N
Canonical SMILES C(CSSCCC(C(=O)O)N)C(C(=O)O)N
Isomeric SMILES C(CSSCCC(C(=O)O)N)C(C(=O)O)N
WGK Germany 3
PubChem CID 10010
分子量 268.35
Beilstein号 1728581
Reaxy-Rn 1728581

化学和物理性质

密度 1.443
熔点 ≥300°C
分子量 268.400 g/mol
XLogP3 -5.600
氢键供体数Hydrogen Bond Donor Count 4
氢键受体数Hydrogen Bond Acceptor Count 8
可旋转键计数Rotatable Bond Count 9
精确质量Exact Mass 268.055 Da
单同位素质量Monoisotopic Mass 268.055 Da
拓扑极表面积Topological Polar Surface Area 177.000 Ų
重原子数Heavy Atom Count 16
形式电荷Formal Charge 0
复杂度Complexity 216.000
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 0
未定义的原子立体中心计数Undefined Atom Stereocenter Count 2
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 1

安全和危险性(GHS)

WGK Germany 3
Reaxy-Rn 1728581
Merck Index 4735
个人防护装备 Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter

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找到3个结果

批号(Lot Number) 证书类型 日期 货号
I2001005 分析证书 24-06-14 H108029
H2026075 分析证书 24-06-14 H108029
H1521026 分析证书 23-09-08 H108029

此产品的引用文献

1. Erfei Dong, Ting Chen, Min Fang, Weiju Zhu, Cun Li.  (2023)  Construction of continuously enhanced fluorescent sensor for detection of glutathione in normal and cancer cells.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  287  (122064).  [PMID:36347165] [10.1016/j.saa.2022.122064]
2. Lili Zhang, Wen Duan, Yan Huang, Yuyu Zhang, Baoguo Sun, Dandan Pu, Yizhuang Tang, Chao Liu.  (2020)  Sensory taste properties of chicken (Hy-Line brown) soup as prepared with five different parts of the chicken.  INTERNATIONAL JOURNAL OF FOOD PROPERTIES,  [10.1080/10942912.2020.1828455]

参考文献

1. M W Orth,Y Bai,I H Zeytun,M E Cook.  (1992-03-01)  Excess levels of cysteine and homocysteine induce tibial dyschondroplasia in broiler chicks..  The Journal of nutrition,  122  ((3)): (482-487).  [PMID:1542006]
2. K Yokoi,H C Lukaski,E O Uthus,F H Nielsen.  (2001-04-04)  Use of bioimpedance spectroscopy to estimate body water distribution in rats fed high dietary sulfur amino acids..  The Journal of nutrition,  131  ((4)): (1302-1308).  [PMID:11285342]
3. L Sosvorová,J Bešťák,M Bičíková,M Mohapl,M Hill,J Kubátová,R Hampl.  (2014-06-09)  Determination of homocysteine in cerebrospinal fluid as an indicator for surgery treatment in patients with hydrocefalus..  Physiological research,  63  ((4)): (521-527).  [PMID:24908094]
4. Jason L Robinson,Renee K Bartlett,Scott V Harding,Edward W Randell,Janet A Brunton,Robert F Bertolo.  (2016-08-27)  Dietary methyl donors affect in vivo methionine partitioning between transmethylation and protein synthesis in the neonatal piglet..  Amino acids,  48  ((12)): (2821-2830).  [PMID:27562792]
5. Seu Ping Guiraud,Ivan Montoliu,Laeticia Da Silva,Loïc Dayon,Antonio Núñez Galindo,John Corthésy,Martin Kussmann,Francois-Pierre Martin.  (2016-10-21)  High-throughput and simultaneous quantitative analysis of homocysteine-methionine cycle metabolites and co-factors in blood plasma and cerebrospinal fluid by isotope dilution LC-MS/MS..  Analytical and bioanalytical chemistry,  409  ((1)): (295-305).  [PMID:27757515]
6. Lei Li,Hiroshi Hasegawa,Niro Inaba,Wataru Yoshioka,Dennis Chang,JianXun Liu,Kimiyoshi Ichida.  (2018-08-01)  Diet-induced hyperhomocysteinemia impairs vasodilation in 5/6-nephrectomized rats..  Amino acids,  50  ((10)): (1485-1494).  [PMID:30062489]
7. Alessio Bocedi,Giorgia Gambardella,Giada Cattani,Simonetta Bartolucci,Danila Limauro,Emilia Pedone,Federica Iavarone,Massimo Castagnola,Giorgio Ricci.  (2020-06-04)  Ultra-rapid glutathionylation of chymotrypsinogen in its molten globule-like conformation: A comparison to archaeal proteins..  Scientific reports,  10  ((1)): (8943-8943).  [PMID:32488029]
8. Josef Bártl,Petr Chrastina,Jakub Krijt,Jakub Hodík,Karolína Pešková,Viktor Kožich.  (2014-08-03)  Simultaneous determination of cystathionine, total homocysteine, and methionine in dried blood spots by liquid chromatography/tandem mass spectrometry and its utility for the management of patients with homocystinuria..  Clinica chimica acta; international journal of clinical chemistry,  437  (211-217).  [PMID:25086281]
9. Chasity B Love-Nkansah,Lei Tan,Joseph S Francisco,Yu Xia.  (2015-11-05)  Gas-Phase Unimolecular Dissociation Reveals Dominant Base Property of Protonated Homocysteine Sulfinyl Radical Ions..  Chemistry (Weinheim an der Bergstrasse, Germany),  22  ((3)): (934-940).  [PMID:26531146]
10. Javier Escobar,Ángel Sánchez-Illana,Julia Kuligowski,Isabel Torres-Cuevas,Rønnaug Solberg,Håvard T Garberg,Marianne U Huun,Ola D Saugstad,Máximo Vento,Consuelo Cháfer-Pericás.  (2016-02-20)  Development of a reliable method based on ultra-performance liquid chromatography coupled to tandem mass spectrometry to measure thiol-associated oxidative stress in whole blood samples..  Journal of pharmaceutical and biomedical analysis,  123  (104-112).  [PMID:26895495]
11. Fumie Nakashima,Takahiro Shibata,Kohei Kamiya,Jun Yoshitake,Ryosuke Kikuchi,Tadashi Matsushita,Isao Ishii,Juan A Giménez-Bastida,Claus Schneider,Koji Uchida.  (2018-01-19)  Structural and functional insights into S-thiolation of human serum albumins..  Scientific reports,  ((1)): (932-932).  [PMID:29343798]
12. Erfei Dong, Ting Chen, Min Fang, Weiju Zhu, Cun Li.  (2023)  Construction of continuously enhanced fluorescent sensor for detection of glutathione in normal and cancer cells.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  287  (122064).  [PMID:36347165] [10.1016/j.saa.2022.122064]
13. Lili Zhang, Wen Duan, Yan Huang, Yuyu Zhang, Baoguo Sun, Dandan Pu, Yizhuang Tang, Chao Liu.  (2020)  Sensory taste properties of chicken (Hy-Line brown) soup as prepared with five different parts of the chicken.  INTERNATIONAL JOURNAL OF FOOD PROPERTIES,  [10.1080/10942912.2020.1828455]

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