硫酸新霉素

规格或纯度: USP级,600 I.U./mg

CAS编号: 1405-10-3
分子式: C₂₃H₄₆N₆O₁₃·3H₂SO₄·xH₂O
分子量: 908.88
EC号: 215-773-1
MDL号: MFCD00077833
PubChem编号: 197162

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货号 (SKU)	包装规格	是否现货
N109017-5g	5g	现货
N109017-25g	25g	现货
N109017-100g	100g	现货
N109017-500g	500g	现货

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化学生物学糖科学

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基本描述

别名	硫酸新霉素\|硫酸新霉素水合物\|新霉素三硫酸盐水合物
英文别名	NEOMYCIN SULFATE\|Framycetin sulfate\|1405-10-3\|Neomycin B sulfate\|28002-70-2\|Framycetin sulphate\|Neomycin B sulphate\|Fradiomycin sulfate\|Neomycin B, sulfate (salt)\|(2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2-[(2S,3R,4S,5R)-4-
规格或纯度	USP级,600 I.U./mg
英文名称	Neomycin sulfate
生化机理	作用方式：与引起错编的 30S 和 50S（有时为 50S）亚基结合；抑制蛋白质合成的开始和延长。抗菌谱：革兰氏阴性和革兰氏阳性细菌。
应用	在没有影响神经元Na+/Ca2+ 反向转运蛋白（antiporter）的情况下阻断电压灵敏的Ca2+ 通道。结合到核糖体30S 和 50S 亚单位引起蛋白错误编码；在蛋白合成起间抑制起始和延长。抗菌谱: 革兰氏阴性和阳性细菌。
储存温度	2-8°C储存,充氩
运输条件	冰袋运输
产品介绍	溶于水。水中溶解度:500 g/L (20°C) 在没有影响神经元Na+/Ca2+ 反向转运蛋白（antiporter）的情况下阻断电压灵敏的Ca2+ 通道。结合到核糖体30S 和 50S 亚单位引起蛋白错误编码；在蛋白合成起间抑制起始和延长。抗菌谱: 革兰氏阴性和阳性细菌。 Neomycin Trisulfate is produced by Streptomyces containing a minimum of 85% neomycin B. It has been used as a selection agent for prokaryotic cells transformed using the neo selectable marker gene, and to study ototoxic side effects of antibiotics, platelet-derived growth factor responses in certain fibroblasts, and extraction of Nuclear Phosphatidylinositol 4,5-Bisphosphate-Interacting Proteins. It is recommended for use in cell culture applications at 50 mg/L.

名称和标识符

EC号	215-773-1
IUPAC Name	(2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2-[(2S,3R,4S,5R)-4-[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-3-hydroxycyclohexyl]oxyoxane-3,4-diol;sulfuric acid
INCHI	InChI=1S/C23H46N6O13.H2O4S/c24-2-7-13(32)15(34)10(28)21(37-7)40-18-6(27)1-5(26)12(31)20(18)42-23-17(36)19(9(4-30)39-23)41-22-11(29)16(35)14(33)8(3-25)38-22;1-5(2,3)4/h5-23,30-36H,1-4,24-29H2;(H2,1,2,3,4)/t5-,6+,7-,8+,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+;/m1./s1
InChi Key	OIXVKQDWLFHVGR-WQDIDPJDSA-N
Canonical SMILES	C1C(C(C(C(C1N)OC2C(C(C(C(O2)CN)O)O)N)OC3C(C(C(O3)CO)OC4C(C(C(C(O4)CN)O)O)N)O)O)N.OS(=O)(=O)O
Isomeric SMILES	C1[C@H]([C@@H]([C@H]([C@@H]([C@H]1N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CN)O)O)N)O[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O[C@@H]4[C@@H]([C@H]([C@@H]([C@@H](O4)CN)O)O)N)O)O)N.OS(=O)(=O)O
WGK Germany	3
RTECS	QP4375000
PubChem CID	197162
分子量	908.88
Reaxy-Rn	9468364

化学和物理性质

溶解性	Soluble in water
敏感性	对光线和湿度敏感
比旋光度	56° (C=10,H2O)

安全和危险性（GHS）

象形图	Health Hazard Harmful
信号词	Danger
危险声明	H335: May cause respiratory irritation H373: Causes damage to organs through prolonged or repeated exposure H412: Harmful to aquatic life with long lasting effects H317: May cause an allergic skin reaction H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled H361: Suspected of damaging fertility or the unborn child
WGK Germany	3
RTECS	QP4375000
Reaxy-Rn	9468364
Merck Index	6454
个人防护装备	dust mask type N95 (US),Eyeshields,Faceshields,Gloves

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参考文献

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硫酸新霉素

库存信息

库存信息

库存信息

库存信息

基本描述

名称和标识符

化学和物理性质

安全和危险性（GHS）

质检证书(COA)

质检报告(COA)

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参考文献