为了获得访问"阿拉丁铁蛋"实时聊天框的流畅支持体验，建议您使用Chrome浏览器或选择360浏览器极速模式(如何切换极速模式?)，感谢您选择我们！
| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| N333806-1mg |
1mg |
期货  |
|
| 英文别名 | (+/-)-Nimodipine-d7 |
|---|---|
| 规格或纯度 | ≥97% |
| 英文名称 | Nimodipine-d7 |
| 储存温度 | -20°C储存 |
| 运输条件 | 超低温冰袋运输 |
| 产品介绍 |
尼莫地平-d7是氘标记的尼莫地平类似物。尼莫地平是二氢吡啶类药物中的L型Ca | 2+ |通道。尼莫地平有几种已报道的作用，特别是在血管和神经元测试系统内。据报道，在麻醉的猫中，尼莫地平的静脉内给药可引起动脉血管扩张。在大鼠中，对尼莫地平对通过各种方法产生的惊厥的影响的研究表明，尼莫地平给药后戊戊四唑惊厥诱发的阈值升高。据报道尼莫地平对脑血管具有选择性，对偏头痛研究可能有用。据报道，对老年大鼠进行慢性尼莫匹定治疗可预防年龄引起的学习障碍，并可能与大脑皮层的突触体Ca | 2+ |结合蛋白的轻微增加有关。 Nimodipine-d7 is a deuterium-labeled analogue of Nimodipine. Nimodipine is a L-type Ca|2+|channel within the dihydropyridine drug class. Nimodipine has several reported effects, specifically within vascular and neuronal test systems. In anesthetized cats, intravenous administration of Nimodipine is reported to cause pial arterial vasodilation. In rats, a study on the effect of Nimodipine on convulsions produced via various methods noted that the threshold of pentylenetetrazol convulsion induction was raised after Nimodipine administration. Nimodipine has also been reported to be selective for cerebral vasculature and may be useful for migraine research studies. Chronic Nimopidine treatment in aged rats has been reported to prevent age-induced learning deficits and may be associated with a slight increase of synaptosomal Ca|2+|binding proteins from the cerebral cortex. |
| IUPAC Name | 5-O-(1,1,1,2,3,3,3-heptadeuteriopropan-2-yl) 3-O-(2-methoxyethyl) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate |
|---|---|
| INCHI | InChI=1S/C21H26N2O7/c1-12(2)30-21(25)18-14(4)22-13(3)17(20(24)29-10-9-28-5)19(18)15-7-6-8-16(11-15)23(26)27/h6-8,11-12,19,22H,9-10H2,1-5H3/i1D3,2D3,12D |
| InChi Key | UIAGMCDKSXEBJQ-QLWPOVNFSA-N |
| Canonical SMILES | CC1=C(C(C(=C(N1)C)C(=O)OC(C)C)C2=CC(=CC=C2)[N+](=O)[O-])C(=O)OCCOC |
| PubChem CID | 91971923 |
| 分子量 | 425.48 |
| 熔点 | 116-121° C |
|---|
输入批号以搜索COA:
首页
400-620-6333
危险品化学品经营许可证（带存储）