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土霉素

四环素类抗生素
176篇引用文献
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货号 (SKU) 包装规格 是否现货 价格 数量
O304654-25g
 25g 现货 Stock Image
O304654-100g
 100g 现货 Stock Image
O304654-500g
 500g 现货 Stock Image
大包装询价 添加到收藏夹 比较  SDS中文版  DATASHEET
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Anti-infection (2827) Antibiotic (625) Bacterial (719) Endogenous Metabolite (978) HSV (104) Metabolic Enzyme/Protease (4886)
main product photo

基本描述

英文别名 Oxyterracine | Terramycin | Terrafungine | Oxitetracyclin | oxytetracycline | Biostat | Oxitetraciclina | Oxymycin | Oxytetracycline anhydrous | Adamycin | Oxytetracyclinum | Oxytetracycline (anhydrous) | Ryomycin | Geomycin | Oxyterracin | Oxytetracyclin
规格或纯度 Moligand™, ≥98%
英文名称 Oxytetracycline
生化机理 四环素类抗生素。抑制线粒体蛋白质合成。体内抗炎作用。
储存温度 2-8°C储存,避光
运输条件 冰袋运输
备注 如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。
产品介绍


Oxytetracycline is an anti-inflammatory, antibiotic, and anti-proliferative agent shown to inhibit mitochondrial protein synthesis. Mechanistic studies show that this compound reduces cytochrome c activity which eventually causes cell growth arrest. Additionally, Oxytetracycline has demonstrated the ability to reduce murine bronchial inflammation. The anti-inflammatory characteristics of this agent are due to its ability to cause a decrease in IL-4, IL-5, IL-13, immune cells, and the ovalbumin-specific IgE. Data suggests that Oxytetracycline is also an inhibitor of NF-κB activation via phosphorylation and degradation of IκB-α.

AI解读

名称和识别符

IUPAC Name (4S,4aR,5S,5aR,6S,12aR)-4-(dimethylamino)-1,5,6,10,11,12a-hexahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide
INCHI InChI=1S/C22H24N2O9/c1-21(32)7-5-4-6-8(25)9(7)15(26)10-12(21)17(28)13-14(24(2)3)16(27)11(20(23)31)19(30)22(13,33)18(10)29/h4-6,12-14,17,25-26,28,30,32-33H,1-3H3,(H2,23,31)/t12-,13-,14+,17+,21-,22+/m1/s1
InChi Key OWFJMIVZYSDULZ-PXOLEDIWSA-N
Canonical SMILES CC1(C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O)O
Isomeric SMILES C[C@@]1([C@H]2[C@@H]([C@H]3[C@@H](C(=O)C(=C([C@]3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O)O
PubChem CID 54675779
分子量 460.43

化学和物理性质

溶解性 Sparingly soluble in aqueous solution at 0.6 mg/mL
敏感性 对空气敏感;对光敏感;对湿度敏感
熔点 183 °C
分子量 460.400 g/mol
XLogP3 -1.600
氢键供体数Hydrogen Bond Donor Count 7
氢键受体数Hydrogen Bond Acceptor Count 10
可旋转键计数Rotatable Bond Count 2
精确质量Exact Mass 460.148 Da
单同位素质量Monoisotopic Mass 460.148 Da
拓扑极表面积Topological Polar Surface Area 202.000 Ų
重原子数Heavy Atom Count 33
形式电荷Formal Charge 0
复杂度Complexity 1000.000
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 6
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 1

安全和危险性（GHS）

象形图 GHS08,   GHS09,   GHS07
信号词 Danger
危险声明

H319: 引起严重眼睛刺激

H302: 吞食有害

H317: 可能引起皮肤过敏反应

H312: 皮肤接触有害

H400: 对水生生物有剧毒

H332: 吸入有害

H410: 对水生生物有剧毒并具有长期持续影响

H360: 可能损害生育力或未出生的孩子

H361: 怀疑破坏生育力或未出生的孩子

H362: 可能对母乳喂养的孩子造成伤害
预防措施声明

P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾

P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。

P273: 避免释放到环境中。

P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。

P302+P352: 如皮肤沾染：用水充分清洗。

P321: 特殊处理（请参阅此标签上的...）。

P405: 密闭存放

P501: 将内容物/容器处理到。。。

P264: 处理后要彻底洗手。

P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。

P271: 仅在室外或通风良好的地方使用。

P270: 使用本产品时，请勿进食、饮水或吸烟。

P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。

P272: 被污染的工作服不允许离开工作场所

P333+P313: 如发生皮肤刺激或皮疹：求医/就诊。

P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。

P391: 收集溢出物

P330: 漱口

P263: 避免在怀孕期间/哺乳期间接触。

P203: 使用前，获取、阅读并遵守所有安全说明。

P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。

P301+P317: 如果被吞咽：请寻求医疗帮助。

P318: 如果暴露或担心，请就医。

P317: 寻求紧急医疗救助。

P337+P317: 如果眼睛刺激持续：寻求医疗帮助。

技术规格说明书

Purity(HPLC) 98-100（%）
Proton NMR spectrum Conforms to structure
LC-MS for identification Conforms

 技术规格说明书

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到17个结果

批号(Lot Number) 证书类型 日期 货号
H2416336 分析证书 24-08-03 O304654
H2416335 分析证书 24-08-03 O304654
H2416334 分析证书 24-08-03 O304654
H2416333 分析证书 24-08-03 O304654
I2306666 分析证书 23-08-09 O304654
I2306665 分析证书 23-08-09 O304654
I2306654 分析证书 23-08-09 O304654
K2216311 分析证书 22-11-23 O304654
J2218329 分析证书 22-10-20 O304654
J2218340 分析证书 22-10-20 O304654
G2328015 分析证书 21-12-21 O304654
E2305087 分析证书 21-12-21 O304654
C2303235 分析证书 21-12-21 O304654
A2214629 分析证书 21-12-21 O304654
A2214628 分析证书 21-12-21 O304654
A2214627 分析证书 21-12-21 O304654
H2231017 分析证书 21-06-17 O304654

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可替换产品

  1. Oxytetracycline (Terramycin)
    Oxytetracycline (Terramycin)

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