| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| R109810-20mg |
20mg |
现货  |
|
| 别名 | 罗通定,左旋四氢巴马汀 |
|---|---|
| 英文别名 | tetrahydropalmatine | 2934-97-6 | Rotundine | 10097-84-4 | DL-Tetrahydropalmatine | ROTUNDINUM | corydalis B | Hyndarin | Tetrahydropalmatine, (+/-)- | CHEMBL187892 | 78F8583LNQ | 2,3,9,10-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline | 2,3,9,10-Tetrameth |
| 规格或纯度 | 分析标准品, ≥98%(HPLC) |
| 英文名称 | Rotundine |
| 储存温度 | 2-8°C储存,避光 |
| 运输条件 | 冰袋运输 |
| 产品介绍 |
无臭，无味；遇光受热易变黄。 |
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| 活性类型 | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
| 分子类型 | 小分子 |
|---|---|
| IUPAC Name | 2,3,9,10-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline |
| INCHI | InChI=1S/C21H25NO4/c1-23-18-6-5-13-9-17-15-11-20(25-3)19(24-2)10-14(15)7-8-22(17)12-16(13)21(18)26-4/h5-6,10-11,17H,7-9,12H2,1-4H3 |
| InChi Key | AEQDJSLRWYMAQI-UHFFFAOYSA-N |
| Canonical SMILES | COC1=C(C2=C(CC3C4=CC(=C(C=C4CCN3C2)OC)OC)C=C1)OC |
| Isomeric SMILES | COC1=C(C2=C(CC3C4=CC(=C(C=C4CCN3C2)OC)OC)C=C1)OC |
| PubChem CID | 5417 |
| 分子量 | 355.427 |
| 密度 | 1.23 |
|---|---|
| 敏感性 | 对光敏感 |
| 熔点 | 141-144°C |
| 分子量 | 355.400 g/mol |
| XLogP3 | 3.200 |
| 氢键供体数Hydrogen Bond Donor Count | 0 |
| 氢键受体数Hydrogen Bond Acceptor Count | 5 |
| 可旋转键计数Rotatable Bond Count | 4 |
| 精确质量Exact Mass | 355.178 Da |
| 单同位素质量Monoisotopic Mass | 355.178 Da |
| 拓扑极表面积Topological Polar Surface Area | 40.200 Ų |
| 重原子数Heavy Atom Count | 26 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 475.000 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 0 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 1 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 0 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 0 |
| 共价键合单元计数Covalently-Bonded Unit Count | 1 |
| Purity(HPLC) | 98-100（%） |
|---|---|
| Proton NMR spectrum | Conforms to Structure |
| 1. Jiawen Ai, Weize Zhao, Quan Yu, Xiang Qian, Jianhua Zhou, Xinming Huo, Fei Tang. (2023) SR-Unet: A Super-Resolution Algorithm for Ion Trap Mass Spectrometers Based on the Deep Neural Network. ANALYTICAL CHEMISTRY, 95 (47): (17407–17415). [PMID:37963290] [10.1021/acs.analchem.3c04172] |
| 2. Cui Li, Liping Li, Yaodong Yi, Wei Wang, Jingqun Yuan, Fuqing Tan, Danbo Fang, Su Zeng, Hui Zhou, Huidi Jiang. (2020) L-tetrahydropalmatine attenuates cisplatin-induced nephrotoxicity via selective inhibition of organic cation transporter 2 without impairing its antitumor efficacy. BIOCHEMICAL PHARMACOLOGY, 177 (114021). [PMID:32389634] [10.1016/j.bcp.2020.114021] |
| 1. Jiawen Ai, Weize Zhao, Quan Yu, Xiang Qian, Jianhua Zhou, Xinming Huo, Fei Tang. (2023) SR-Unet: A Super-Resolution Algorithm for Ion Trap Mass Spectrometers Based on the Deep Neural Network. ANALYTICAL CHEMISTRY, 95 (47): (17407–17415). [PMID:37963290] [10.1021/acs.analchem.3c04172] |
| 2. Cui Li, Liping Li, Yaodong Yi, Wei Wang, Jingqun Yuan, Fuqing Tan, Danbo Fang, Su Zeng, Hui Zhou, Huidi Jiang. (2020) L-tetrahydropalmatine attenuates cisplatin-induced nephrotoxicity via selective inhibition of organic cation transporter 2 without impairing its antitumor efficacy. BIOCHEMICAL PHARMACOLOGY, 177 (114021). [PMID:32389634] [10.1016/j.bcp.2020.114021] |
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