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D-酪氨酸

42篇引用文献
  • ≥98%
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货号 (SKU) 包装规格 是否现货 价格 数量
T101403-1g
 1g 现货 Stock Image
T101403-5g
 5g 现货 Stock Image
T101403-25g
 25g 现货 Stock Image
T101403-100g
 100g 现货 Stock Image
T101403-500g
 500g 现货 Stock Image
大包装询价 添加到收藏夹 比较  SDS中文版  DATASHEET
查看相关系列
Metabolic Enzyme/Protease (4884) Tyrosinase (70) 化学生物学 (1259) 肽化学 (313)
main product photo

基本描述

别名 3-(4-羟基苯基)-D-丙氨酸 | (R)-2-氨基-3-(4-羟基苯基)丙酸 | D-酪胺酸
英文别名 CCRIS 7710 | myo-Inositol hexanicotinate | DB03839 | d-p-Tyrosine | (R)-2-Amino-3-(p-hydroxyphenyl)propionic acid | Q16082044 | 3-(4-Hydroxyphenyl)-D-alanine | C06420 | AS-11715 | (2R)-2-Amino-3-(4-hydroxyphenyl)propanoic acid; (R)-Tyrosine; D-p-Tyrosine
规格或纯度 ≥98%
英文名称 D-Tyrosine
应用 用作生化试剂，也可作为研究蛋白质结构和动力学的探针。
运输条件 常规运输
产品介绍

它与L-酪氨酸是光学异构体，系非蛋白质氨基酸。不溶于一般中性有机溶剂如无水乙醇、乙醚、丙酮等。 用作生化试剂，也可作为研究蛋白质结构和动力学的探针。

application：

D-Tyrosine is synthesized from phenylalanine. It is also the precursor of epinephrine, thyroid hormones, and melanin.

AI解读

关联靶点（人）

CA2 Tclin Carbonic anhydrase II (17698 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CA1 Tclin Carbonic anhydrase I (13240 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SLC7A5 Tchem L-type amino acid transporter 1 (388 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
RGS4 Tchem Regulator of G-protein signaling 4 (13867 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MEN1 Tchem Menin/Histone-lysine N-methyltransferase MLL (48157 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

关联靶点（其它种属）

Carbonic anhydrase (69 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Staphylococcus aureus (210822 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Slc16a10 Monocarboxylate transporter 10 (73 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Carbonic anhydrase-like protein, putative (25 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

名称和识别符

PubChem SID 488184644
分子类型 小分子
IUPAC Name (2R)-2-amino-3-(4-hydroxyphenyl)propanoic acid
INCHI InChI=1S/C9H11NO3/c10-8(9(12)13)5-6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13)/t8-/m1/s1
InChi Key OUYCCCASQSFEME-MRVPVSSYSA-N
Canonical SMILES C1=CC(=CC=C1CC(C(=O)O)N)O
Isomeric SMILES C1=CC(=CC=C1C[C@H](C(=O)O)N)O
PubChem CID 71098
分子量 181.19
Beilstein号 14605
Reaxy-Rn 2212157

化学和物理性质

溶解性 Soluble in water
比旋光度 +10.3°, c = 5 in 1 M HCl
熔点 310-314°C
分子量 181.190 g/mol
XLogP3 -2.300
氢键供体数Hydrogen Bond Donor Count 3
氢键受体数Hydrogen Bond Acceptor Count 4
可旋转键计数Rotatable Bond Count 3
精确质量Exact Mass 181.074 Da
单同位素质量Monoisotopic Mass 181.074 Da
拓扑极表面积Topological Polar Surface Area 83.600 Ų
重原子数Heavy Atom Count 13
形式电荷Formal Charge 0
复杂度Complexity 176.000
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 1
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 1

安全和危险性（GHS）

象形图 GHS07
信号词 Warning
危险声明

H315: 引起皮肤刺激

H319: 引起严重眼睛刺激

H335: 可能引起呼吸道刺激
预防措施声明

P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾

P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。

P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。

P302+P352: 如皮肤沾染：用水充分清洗。

P321: 特殊处理（请参阅此标签上的...）。

P405: 密闭存放

P501: 将内容物/容器处理到。。。

P264: 处理后要彻底洗手。

P271: 仅在室外或通风良好的地方使用。

P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。

P403+P233: 存放在通风良好的地方。保持容器密闭。

P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。

P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。

P337+P317: 如果眼睛刺激持续：寻求医疗帮助。

P332+P317: 如果出现皮肤刺激：请寻求医疗帮助。

P319: 如果你感到不适，请寻求医疗帮助。
Reaxy-Rn 2212157
Merck Index 9839
个人防护装备 dust mask type N95 (US), Eyeshields, Gloves

技术规格说明书

Specific Rotation [a]20/D(c=5 in 1N HCl) 10-12（°）
Purity(HPLC) 98-100（%）
Appearance（T101403) White to Off-White Powder or Crystals
Proton NMR spectrum Conforms to Structure

 技术规格说明书

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到14个结果

批号(Lot Number) 证书类型 日期 货号
K2413407 分析证书 24-10-17 T101403
K2413408 分析证书 24-10-17 T101403
K2421164 分析证书 24-10-17 T101403
K2421165 分析证书 24-10-17 T101403
D2422241 分析证书 24-03-20 T101403
D2416476 分析证书 24-03-20 T101403
D2416477 分析证书 24-03-20 T101403
J1930172 分析证书 23-08-08 T101403
B2208497 分析证书 21-12-18 T101403
B2208514 分析证书 21-12-18 T101403
B2208515 分析证书 21-12-18 T101403
B2208516 分析证书 21-12-18 T101403
B2208519 分析证书 21-12-18 T101403
E2326315 分析证书 21-12-18 T101403

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此产品的引用文献

如何在您的发表作品中引用阿拉丁的产品和网站?
1. Jingzhi Yang, Yami Ran, Shaopeng Liu, Chenhao Ren, Yuntian Lou, Pengfei Ju, Guoliang Li, Xiaogang Li, Dawei Zhang.  (2023)  Synergistic D-Amino Acids Based Antimicrobial Cocktails Formulated via High-Throughput Screening and Machine Learning.  Advanced Science,  11  (9): (2307173).  [PMID:38126652] [10.1002/advs.202307173]
2. Yang Li, Bingxuan Ji, Ziyang Chen, Zhenghua Zhang.  (2023)  Polydopamine and d-tyrosine-functionalized PTFE membrane for membrane distillation of secondary effluent: Fouling mitigation and mechanism.  JOURNAL OF MEMBRANE SCIENCE,  683  (121857).  [10.1016/j.memsci.2023.121857]
3. Yuhe Shen, Dongshuang Jia, Yuefei Wang, Tao Yu, Xiaojian Xu, Heng Chang, Qing Li, Rongxin Su, Wei Qi.  (2023)  Enzymatic oxidation of tyrosine enantiomers into biomimetic pigments with enhanced performance for hair dyeing.  DYES AND PIGMENTS,  216  (111360).  [10.1016/j.dyepig.2023.111360]
4. Ning Liu, Junyao Li, Wenrong Cai, Datong Wu, Yong Kong.  (2023)  Chiral Metal–Organic Framework with Temperature-Dependent Homochirality for Chiral Discrimination.  ANALYTICAL CHEMISTRY,  95  (15): (6467–6475).  [PMID:37029721] [10.1021/acs.analchem.3c01316]
5. Hou Huipeng, Tang Shanshan, Wang Wei, Liu Miao, Liang Axin, Xie Bingteng, Yi Yue, Luo Aiqin.  (2023)  Electrochemical Chiral Recognizing Tryptophan Enantiomers Based on Chiral Metal-Organic Framework D-MOF.  CHEMICAL RESEARCH IN CHINESE UNIVERSITIES,  39  (6): (976-984).  [10.1007/s40242-023-3004-6]
6. Hao Gou, Jingxian He, Rong Nie, Daqian Xu, Honghong Rao, Guohu Zhao.  (2023)  A stable electrochemical chiral interface based on graphene-chitosan composites for tyrosine enantiomers recognition.  MICROCHEMICAL JOURNAL,  190  (108712).  [10.1016/j.microc.2023.108712]
7. Xinying Su, Jintao Luo, Yu Wang, Jinghao Dong, Yu Tian.  (2023)  Biofouling mitigation by D-tyrosine in membrane bioreactor: Short-term performance.  Journal of Environmental Chemical Engineering,  11  (109554).  [10.1016/j.jece.2023.109554]
8. Hongyi Li, Yifu Wang, Xinxin Zhao, Zhen Yan, Chao Song, Shuguang Wang.  (2023)  Chirality of tyrosine controls biofilm formation via the regulation of bacterial adhesion.  BIOCHEMICAL ENGINEERING JOURNAL,  192  (108844).  [10.1016/j.bej.2023.108844]
9. Wen-Rong Cai, Wen-Kai Zhu, Bao-Zhu Yang, Da-Tong Wu, Jun-Yao Li, Zheng-Zhi Yin, Yong Kong.  (2022)  Porphyrin-Based Metal–Organic Frameworks for Efficient Electrochemiluminescent Chiral Recognition of Tyrosine Enantiomers.  Chemosensors,  10  (12): (519).  [10.3390/chemosensors10120519]
10. Zixuan Liu, Zheng-Zhi Yin, Guojun Zheng, Hongyu Zhang, Min Zhou, Shan Li, Yong Kong.  (2022)  Dual-template molecularly imprinted electrochemical biosensor for IgG-IgM combined assay based on a dual-signal strategy.  BIOELECTROCHEMISTRY,  148  (108267).  [PMID:36148758] [10.1016/j.bioelechem.2022.108267]
11. Yiyi Liu, Fangling Wu, Jiabin Wang, Ling Pu, Chuan-Fan Ding.  (2022)  Simultaneous chirality separation of amino acids and their derivative by natamycin based on mobility measurements.  ANALYTICA CHIMICA ACTA,  1227  (340298).  [PMID:36089312] [10.1016/j.aca.2022.340298]
12. Ning Liu, Baozhu Yang, Zheng-Zhi Yin, Wenrong Cai, Junyao Li, Yong Kong.  (2022)  A chiral sensing platform based on chiral metal-organic framework for enantiodiscrimination of the isomers of tyrosine and tryptophan.  JOURNAL OF ELECTROANALYTICAL CHEMISTRY,  918  (116445).  [10.1016/j.jelechem.2022.116445]
13. Datong Wu, Cong Ma, Ting Wan, Pengfen Zhu, Yong Kong.  (2022)  Strategies to synthesize a chiral helical polymer accompanying with two stereogenic centers for chiral electroanalysis.  ANALYTICA CHIMICA ACTA,  1206  (339810).  [PMID:35473883] [10.1016/j.aca.2022.339810]
14. Shutong Yang, Liancheng Gu, Fangling Wu, Xinhua Dai, Fuxing Xu, Qiaoyu Li, Xiang Fang, Shaoning Yu, Chuan-Fan Ding.  (2022)  The chirality determination of amino acids by forming complexes with cyclodextrins and metal ions using ion mobility spectrometry, and a DFT calculation.  TALANTA,  243  (123363).  [PMID:35272154] [10.1016/j.talanta.2022.123363]
15. Xiaohui Niu, Simeng Yan, Letong Wang, Jinliang Chen, Rui Zhao, Hongxia Li, Jian Liu, Kunjie Wang.  (2022)  Induction of chiral polymers from metal-organic framework for stereoselective recognition.  ANALYTICA CHIMICA ACTA,  1196  (339546).  [PMID:35151404] [10.1016/j.aca.2022.339546]
16. Qingfang Niu, Pengyue Jin, Yu Huang, Lifang Fan, Caihong Zhang, Cheng Yang, Chuan Dong, Wenting Liang, Shaomin Shuang.  (2022)  A selective electrochemical chiral interface based on a carboxymethyl-β-cyclodextrin/Pd@Au nanoparticles/3D reduced graphene oxide nanocomposite for tyrosine enantiomer recognition.  ANALYST,  147  (5): (880-888).  [PMID:35137747] [10.1039/D1AN02262H]
17. Xiaohui Niu, Simeng Yan, Jinliang Chen, Hongxia Li, Kunjie Wang.  (2022)  Enantioselective recognition of L/D-amino acids in the chiral nanochannels of a metal-organic framework.  ELECTROCHIMICA ACTA,  405  (139809).  [10.1016/j.electacta.2021.139809]
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19. Jinglei Liu, Wenbo Yuan, Caifeng Li, Mengmeng Cheng, Yan Su, Lijian Xu, Tianfei Chu, Shifeng Hou.  (2021)  l-Cysteine-Modified Graphene Oxide-Based Membrane for Chiral Selective Separation.  ACS Applied Materials & Interfaces,  13  (41): (49215–49223).  [PMID:34628847] [10.1021/acsami.1c14900]
20. Qianqian Zhao, Wenrong Cai, Baozhu Yang, Zheng-Zhi Yin, Datong Wu, Yong Kong.  (2021)  Electrochemiluminescent chiral discrimination with chiral Ag2S quantum dots/few-layer carbon nitride nanosheets.  ANALYST,  146  (20): (6245-6251).  [PMID:34528650] [10.1039/D1AN01437D]
21. Zhan Gao, Zhihao Yu, Xiaoli Zhang, Shougang Fan, Huiyu Gao, Caini Liu, Qixing Zhou, Huaiqi Shao, Lan Wang, Xiaoyan Guo.  (2021)  Exploration on Optimized Control Way of D-Amino Acid for Efficiently Mitigating Membrane Biofouling of Membrane Bioreactor.  Membranes,  11  (8): (612).  [PMID:34436375] [10.3390/membranes11080612]
22. Qianqian Zhao, Datong Wu, Zheng-Zhi Yin, Wenrong Cai, Haifeng Zhou, Yong Kong.  (2021)  Fluorometric discrimination of tyrosine isomers based on the inner filter effect of chiral Au nanoparticles on MoS2 quantum dots.  Analytical Methods,  13  (20): (2290-2296).  [PMID:33969836] [10.1039/D1AY00145K]
23. Liu Nijuan, Liu Jingjing, Niu Xiaohui, Wang Jia, Guo Ruibin, Mo Zunli.  (2021)  An electrochemical chiral sensor based on the synergy of chiral ionic liquid and 3D-NGMWCNT for tryptophan enantioselective recognition.  MICROCHIMICA ACTA,  188  (5): (1-13).  [PMID:33839948] [10.1007/s00604-021-04818-w]
24. Lamei Yang, Feng Luo, Weili Wei.  (2021)  Simultaneous determination of the concentration and enantiomeric excess of amino acids with a coumarin-derived achiral probe.  Analytical Methods,  13  (16): (1905-1910).  [PMID:33913945] [10.1039/D1AY00271F]
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29. Huali Liu, Zhen Li, Yan Yan, Jiaqi Zhao, Yu Wang.  (2019)  Chiroptical study of the bimetal–cysteine hybrid composite: interaction between cysteine and Au/Ag alloyed nanotubes.  Nanoscale,  11  (45): (21990-21998).  [PMID:31710078] [10.1039/C9NR07421J]
30. Jiao Zou, Jin-Gang Yu.  (2019)  Chiral recognition of tyrosine enantiomers on a novel bis-aminosaccharides composite modified glassy carbon electrode.  ANALYTICA CHIMICA ACTA,  1088  (35).  [PMID:31623714] [10.1016/j.aca.2019.08.018]
31. Xiaoyan Guo, Shougang Fan, Yandi Hu, Xiaolin Fu, Huaiqi Shao, Qixing Zhou.  (2019)  A novel membrane biofouling mitigation strategy of D-amino acid supported by polydopamine and halloysite nanotube.  JOURNAL OF MEMBRANE SCIENCE,  579  (131).  [10.1016/j.memsci.2019.02.039]
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33. Huang Lu, Li Yanxia, Lin Qi, Lou Benyong, Chen Yiting.  (2018)  Enantioselective permeations of amino acids through l-proline-modified gold nanochannel membrane: an experimental and theoretical study.  AMINO ACIDS,  50  (11): (1549-1556).  [PMID:30073606] [10.1007/s00726-018-2629-0]
34. Datong Wu, Wensheng Tan, Yin Yu, Baozhu Yang, Hongda Li, Yong Kong.  (2018)  A facile avenue to prepare chiral graphene sheets as electrode modification for electrochemical enantiorecognition.  ANALYTICA CHIMICA ACTA,  1033  (58).  [PMID:30172332] [10.1016/j.aca.2018.06.029]
35. Lili Guo, Baozhu Yang, Datong Wu, Yongxin Tao, Yong Kong.  (2018)  Chiral Sensing Platform Based on the Self-Assemblies of Diphenylalanine and Oxalic Acid.  ANALYTICAL CHEMISTRY,  90  (8): (5451–5458).  [PMID:29595059] [10.1021/acs.analchem.8b00762]
36. Yin Yu, Yongxin Tao, Baozhu Yang, Datong Wu, Yong Qin, Yong Kong.  (2017)  Smart Chiral Sensing Platform with Alterable Enantioselectivity.  ANALYTICAL CHEMISTRY,  89  (23): (12930–12937).  [PMID:29125282] [10.1021/acs.analchem.7b03783]
37. Guo Yanyang, Yao Runrun, Wang Zimeng, Zhang Yufan, Cui Mengjing, Zhao Qiuyue, Wang Huan.  (2018)  Novel potential type electrochemical chiral recognition biosensor for amino acid.  JOURNAL OF SOLID STATE ELECTROCHEMISTRY,  22  (1): (41-49).  [10.1007/s10008-017-3719-8]
38. Yongxin Tao, Xiaogang Gu, Baozhu Yang, Linhong Deng, Liping Bao, Yong Kong, Fuqiang Chu, Yong Qin.  (2017)  Electrochemical Enantioselective Recognition in a Highly Ordered Self-Assembly Framework.  ANALYTICAL CHEMISTRY,  89  (3): (1900–1906).  [PMID:28208293] [10.1021/acs.analchem.6b04377]
39. Bei-Bei Jiang, Xue-Fei Sun, Lin Wang, Si-Yu Wang, Ru-Dong Liu, Shu-Guang Wang.  (2017)  Polyethersulfone membranes modified with D-tyrosine for biofouling mitigation: Synergistic effect of surface hydrophility and anti-microbial properties.  CHEMICAL ENGINEERING JOURNAL,  311  (135).  [10.1016/j.cej.2016.11.088]
40. Fang Gao, Shiyao Ma, Xincai Xiao, Yan Hu, Dan Zhao, Zhike He.  (2017)  Sensing tyrosine enantiomers by using chiral CdSe/CdS quantum dots capped with N-acetyl-l-cysteine.  TALANTA,  163  (102).  [PMID:27886758] [10.1016/j.talanta.2016.10.091]
41. Liping Bao, Jiangying Dai, Lin Yang, Jianfeng Ma, Yongxin Tao, Linhong Deng, Yong Kong.  (2015)  Electrochemical Recognition of Tyrosine Enantiomers Based on Chiral Ligand Exchange with Sodium Alginate as the Chiral Selector.  JOURNAL OF THE ELECTROCHEMICAL SOCIETY,  162  (7): (H486).  [10.1149/2.0051508jes]
42. Runqiu Nie, Xiangjie Bo, Huan Wang, Lijun Zeng, Liping Guo.  (2013)  Chiral electrochemical sensing for tyrosine enantiomers on glassy carbon electrode modified with cysteic acid.  ELECTROCHEMISTRY COMMUNICATIONS,  27  (112).  [10.1016/j.elecom.2012.11.014]

参考文献

1. Jingzhi Yang, Yami Ran, Shaopeng Liu, Chenhao Ren, Yuntian Lou, Pengfei Ju, Guoliang Li, Xiaogang Li, Dawei Zhang.  (2023)  Synergistic D-Amino Acids Based Antimicrobial Cocktails Formulated via High-Throughput Screening and Machine Learning.  Advanced Science,  11  (9): (2307173).  [PMID:38126652] [10.1002/advs.202307173]
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