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D-色氨酸, HCA 3 受体激动剂

71篇引用文献
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货号 (SKU) 包装规格 是否现货 价格 数量
T105704-25g
 25g 现货 Stock Image
T105704-100g
 100g 现货 Stock Image
T105704-250g
 250g 现货 Stock Image
T105704-500g
 500g 现货 Stock Image
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HCA3 receptor Agonist (12)
main product photo

基本描述

别名 D-(+)-色氨酸,D-2-氨基-3-吲哚基-1 丙酸,(R)-2-氨基-3-(3-吲哚基)丙酸, D-α-氨基-3-吲哚丙酸
英文别名 Q27077125 | CAS-153-94-6 | MFCD00005647 | BDBM50043799 | D(+)-Tryptophan | D-TRYPTOPHANE | H-delta-TRP-oh | NSC 97942 | DTR | J-300262 | BCP16808 | SMR000059103 | AFA369F6-7A19-42E1-B9E9-0156A2BCE50B | HY-W012479 | Q27115085 | s6253 | HDTrpOH | H-D-Trp-OH
规格或纯度 Moligand™, ≥98%
英文名称 D-Tryptophan
生化机理 低水平的 D-色氨酸能够阻止大肠杆菌中需要 L-色氨酸的突变体的生长。
运输条件 常规运输
作用类型 激动剂
作用机制 HCA 3 受体激动剂
产品介绍

色氨酸是人体必需的标准氨基酸之一。它被细胞用来制造蛋白质。


产品用途：
D-色氨酸可用于人胚肾细胞 (HEK-293，ATCC：CRL-1573) 培养。该产品是一种甜味剂，用于研究由糖引发的肠内分泌细胞中肠促胰岛素的释放，但不是由甜味剂引发的。 用D-色氨酸在体外研究了其在牙科单元水线（DUWLs）中分散生物膜的效果。

Product Description
Tryptophan is one of the essential and standard amino acids present in the body. It is used by the cells to produce proteins.

Product Application
D-TRYPTOPHAN can be used to culture human embryonic kidney cells (HEK-293, ATCC: crl-1573). The product is a sweetener, which is used to study the release of incretin in intestinal endocrine cells induced by sugar, but not by sweetener. D-Tryptophan has been used to study its efficacy on dispersing biofilm in dental unit waterlines (DUWLs) in vitro.

AI解读

关联靶点（人）

HCAR3 Tchem 羟基羧酸受体 3(Hydroxycarboxylic acid receptor 3) (1 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
DHFR Tclin Dihydrofolate reductase (3072 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CA2 Tclin Carbonic anhydrase II (17698 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CA3 Tclin Carbonic anhydrase III (753 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CA6 Tclin Carbonic anhydrase VI (993 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CA1 Tclin Carbonic anhydrase I (13240 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CA5B Tclin Carbonic anhydrase VB (957 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CA5A Tclin Carbonic anhydrase VA (1168 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CA14 Tclin Carbonic anhydrase XIV (1305 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MMP3 Tchem Matrix metalloproteinase 3 (3433 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CA12 Tclin Carbonic anhydrase XII (6231 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CA9 Tclin Carbonic anhydrase IX (8255 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SLC7A5 Tchem L-type amino acid transporter 1 (388 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HTT Tchem Huntingtin (19182 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
LMNA Tbio Prelamin-A/C (36751 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GMNN Tbio Geminin (128009 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PMP22 Tbio Peripheral myelin protein 22 (699 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
RGS4 Tchem Regulator of G-protein signaling 4 (13867 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
RUNX1 Tbio Runt-related transcription factor 1/Core-binding factor subunit beta (7867 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TAS1R3 Tbio T1R1/T1R3 (473 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

关联靶点（其它种属）

Ca7 Carbonic anhydrase VII (3 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Ca13 Carbonic anhydrase XIII (322 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CA4 Carbonic anhydrase IV (1713 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Hdac6 Histone deacetylase 6 (222 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Carbonic anhydrase (69 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Plasmodium falciparum (966862 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GCN5 Histone acetyltransferase GCN5 (89 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
pfk 6-phospho-1-fructokinase (7870 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Ca15 Carbonic anhydrase 15 (173 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CAN2 Carbonic anhydrase 2 (140 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Slc16a10 Monocarboxylate transporter 10 (73 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ispF 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (31 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Carbonic anhydrase-like protein, putative (25 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

名称和识别符

PubChem SID 488180930
EC号 205-819-9
分子类型 小分子
IUPAC Name (2R)-2-amino-3-(1H-indol-3-yl)propanoic acid
INCHI InChI=1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)/t9-/m1/s1
InChi Key QIVBCDIJIAJPQS-SECBINFHSA-N
Canonical SMILES C1=CC=C2C(=C1)C(=CN2)CC(C(=O)O)N
Isomeric SMILES C1=CC=C2C(=C1)C(=CN2)C[C@H](C(=O)O)N
WGK Germany 3
RTECS YN6129000
PubChem CID 9060
分子量 204.23
Beilstein号 86198
Reaxy-Rn 86198

化学和物理性质

溶解性 Soluble in 0.5M hydrochloric acid (50 mg/ml), water (11 mg/ml at 20°C), hot alcohol, and dimethyl sulfoxide. Insoluble in chloroform.
密度 1.362
比旋光度 31 ° (C=1, H2O)
熔点 282-285°C
分子量 204.220 g/mol
XLogP3 -1.100
氢键供体数Hydrogen Bond Donor Count 3
氢键受体数Hydrogen Bond Acceptor Count 3
可旋转键计数Rotatable Bond Count 3
精确质量Exact Mass 204.09 Da
单同位素质量Monoisotopic Mass 204.09 Da
拓扑极表面积Topological Polar Surface Area 79.100 Ų
重原子数Heavy Atom Count 15
形式电荷Formal Charge 0
复杂度Complexity 245.000
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 1
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 1

安全和危险性（GHS）

象形图 GHS07
信号词 Warning
危险声明

H315: 引起皮肤刺激

H319: 引起严重眼睛刺激

H335: 可能引起呼吸道刺激
预防措施声明

P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾

P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。

P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。

P302+P352: 如皮肤沾染：用水充分清洗。

P321: 特殊处理（请参阅此标签上的...）。

P405: 密闭存放

P501: 将内容物/容器处理到。。。

P264: 处理后要彻底洗手。

P271: 仅在室外或通风良好的地方使用。

P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。

P403+P233: 存放在通风良好的地方。保持容器密闭。

P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。

P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。

P337+P317: 如果眼睛刺激持续：寻求医疗帮助。

P332+P317: 如果出现皮肤刺激：请寻求医疗帮助。

P319: 如果你感到不适，请寻求医疗帮助。
WGK Germany 3
RTECS YN6129000
Reaxy-Rn 86198
个人防护装备 Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter

技术规格说明书

Purity(HPLC) 98-100（%）
Specific Rotation [a]20/D(c=1 in H2O) 29-33（°）
Appearance（T105704) White to Off-White Powder
Solubility in 0.5 M HCl，Colorless to Dark Yellow Clear to Hazy,50mg/ml pass
Proton NMR spectrum Conforms to Structure
Nitrogen by Elemental Analysis 13.4-14.1（%）
Carbon by Elemental Analysis 63-67（%）

 技术规格说明书

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找到23个结果

批号(Lot Number) 证书类型 日期 货号
G2411479 分析证书 24-06-12 T105704
G2411478 分析证书 24-06-12 T105704
K2404410 分析证书 23-08-19 T105704
I2311734 分析证书 23-08-19 T105704
I2311733 分析证书 23-08-19 T105704
I2311421 分析证书 23-08-19 T105704
I2311326 分析证书 23-08-19 T105704
I2311123 分析证书 23-08-19 T105704
I2311120 分析证书 23-08-19 T105704
I2311119 分析证书 23-08-19 T105704
I2311092 分析证书 23-08-19 T105704
I2311091 分析证书 23-08-19 T105704
D1824095 分析证书 22-02-16 T105704
G2315056 分析证书 22-01-11 T105704
E2304293 分析证书 22-01-11 T105704
E2304287 分析证书 22-01-11 T105704
C2507027 分析证书 22-01-11 T105704
B2517318 分析证书 22-01-11 T105704
B2223442 分析证书 22-01-11 T105704
B2223439 分析证书 22-01-11 T105704
B2223435 分析证书 22-01-11 T105704
B2223434 分析证书 22-01-11 T105704
B2223383 分析证书 22-01-11 T105704

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