|别名||对氨基酚盐酸盐 ;对氨基苯酚盐酸盐,4-氨基苯酚盐酸盐,盐酸对氨基酚,毛皮棕P,乌尔兹P,毛皮棕P盐,盐酸-4-氨基酚;4-Aminophenol hydrochloride 4-Hydroxyaniline hydrochloride|
|个人防护设备||dust mask type N95 (US),Eyeshields,Faceshields,Gloves|
Pseudomonas aeruginosa strain HJ1012 was isolated on paracetamol as a sole carbon and energy source. This organism could completely degrade paracetamol as high as 2200?mg/L. Following paracetamol cons...Read More
This theoretical and experimental study describes the design and evaluation of the free-radical scavenging effect for the molecular association of 4-aminophenol and salicylate derivatives. For this pu...Read More
Graphene-modified Interdigitated Array Electrode: Fabrication, Characterization, and Electrochemical Immunoassay Application.
We have developed a new procedure for fabricating interdigitated array gold electrodes (Au-IDA) modified with reduced graphene oxide (rGO). In this procedure, we coated the gold surface of the microm...Read More
Kidney injury biomarkers have been utilized by pharmaceutical companies as a means to assess the potential of candidate drugs to induce nephrotoxicity. Multiple platforms and assay methods exist, but ...Read More
AAN effective sensor: The two-photon turn-on fluorescent probe NHU was synthesized to optically detect tyrosinase activity in vitro and in melanoma cells. NHU is composed of a 4-aminophenol moiety and...Read More
Stability-Indicating TLC-Densitometric Method for Simultaneous Determination of Paracetamol and Chlorzoxazone and their Toxic Impurities.
A highly sensitive, selective and accurate thin-layer chromatographic (TLC)-densitometric method has been developed and validated for the simultaneous determination of paracetamol (PAR) and chlorzoxaz...Read More
Highly sensitive sequential injection determination of p-aminophenol in paracetamol formulations with 18-molybdodiphosphate heteropoly anion based on elimination of Schlieren effect.
A highly sensitive, precise and automated method using sequential injection analysis to assay quantitatively low levels of the p-aminophenol (PAP) in paracetamol formulations has been developed. A sol...Read More
In this work, a novel immunosensing method has been developed on the basis of the sensitive determination of a product generated by an enzyme reaction with dual amplification system combining an elect...Read More
A Pt layer/Pt disk electrode configuration to evaluate respiration and alkaline phosphatase activities of mouse embryoid bodies.
A Pt layer/Pt disk electrode configuration was used as a scanning electrochemical microscopy (SECM) probe. The glass seal part of the insulator was covered with a Pt layer to form an exposed pseudo re...Read More
Separation and electrochemical detection of paracetamol and 4-aminophenol in a paper-based microfluidic device
The present work describes the construction and application of a simple, low cost and sensitive microfluidic paper-based device with electrochemical detection for the detection of paracetamol and 4-am...Read More
A manganese oxide with phenol groups as a promising structural model for water oxidizing complex in Photosystem II: a 'golden fish'.
We describe here the ability of manganese oxide monosheets to aggregate to form layered structures with 4-aminophenol molecules. These aggregated monosheets could be considered as the first step to sy...Read More
This paper reports chemical-chemical (CC) and electrochemical-chemical-chemical (ECC) redox cycling, for use in ultrasensitive biosensor applications. A triple chemical amplification approach using an...Read More
Production of p-acetaminophenol by whole-cell catalysis using Escherichia coli overexpressing bacterial aryl acylamidase.
Aryl acylamidase (EC 18.104.22.168, AAA) acts on the amide bond between aryl and acyl groups. Whole cells of Escherichia coli overexpressing a novel bacterial AAA synthesized p-acetaminophenol (p-AAP) from...Read More
Redox cycling compounds have been reported to cause false positive inhibition of proteases in drug discovery studies. This kind of false positives can lead to unusually high hit rates in high-throughp...Read More
Catalytic reduction of 4-nitrophenol using biogenic gold and silver nanoparticles derived from Breynia rhamnoides.
A simple, green method is described for the synthesis of Gold (Au) and Silver (Ag) nanoparticles (NPs) from the stem extract of Breynia rhamnoides. Unlike other biological methods for NP synthesis, th...Read More
An electrochemical sensor for p-aminophenyl phosphate (pAPP) is reported. It is based on the electrochemical conversion of 4-aminophenol (4AP) at a quantum dot (QD) modified electrode under illuminati...Read More
Voltammetric determination of glutathione in haemolysed erythrocyte and tablet samples using modified-multiwall carbon nanotubes paste electrode.
A chemically modified electrode was prepared by incorporating p-aminophenol into multiwall carbon nanotubes paste matrix. Cyclic voltammetry, square wave voltammetry, double potential step chronoamper...Read More
Facile synthesis of two-dimensional graphene/SnO? /Pt ternary hybrid nanomaterials and their catalytic properties.
In this paper, we reported a simple, aqueous-phase route to the synthesis of two-dimensional graphene/SnO(2) composite nanosheets (GSCN) hybrid nanostructures consisting of 5 nm Pt nanoparticles suppo...Read More
Simultaneous determination of N-acetyl-p-aminophenol and p-aminophenol with poly(3,4-ethylenedioxythiophene) modified glassy carbon electrode.
A sensitive and selective method was developed for the determination of N-acetyl-p-aminophenol (APAP) and p-aminophenol (PAP) using poly(3,4-ethylenedioxythiophene) (PEDOT)-modified glassy carbon elec...Read More
Three bacterial strains utilizing paracetamol as the sole carbon, nitrogen, and energy source were isolated from a paracetamol-degrading aerobic aggregate, and assigned to species of the genera Stenot...Read More
Facile synthesis of highly dispersed palladium/polypyrrole nanocapsules for catalytic reduction of p-nitrophenol.
In this study, a facile one-step redox polymerization method for the preparation of highly dispersed palladium (Pd)/polypyrrole (PPy) nanocapsules has been demonstrated. During the polymerizaion proce...Read More
p-Aminophenol-induced cytotoxicity in Jurkat T cells: protective effect of 2(RS)-n-propylthiazolidine-4(R)-carboxylic acid.
Acetaminophen (APAP) is hepatotoxic and can cause toxicity in Jurkat T cells. p-Aminophenol (PAP), an industrial chemical and APAP metabolite, is nephrotoxic and hepatotoxic. Its potential toxicity in...Read More
Bimetallic nanoparticles are considered the next generation of nanocatalysts with increased stability and catalytic activity. Bio-supported synthesis of monometallic nanoparticles has been proposed as...Read More
Amine-functionalized polyglycidyl methacrylate microsphere as a unified template for the synthesis of gold nanoparticles and single-crystal gold plates.
Polyglycidyl methacrylate (PGMA) microspheres, crosslinked and surface-functionalized by amine, can be used as a solid-state template for the synthesis of gold (Au) crystals in the forms of either nan...Read More
Nanoaggregates of a pentacenequinone derivative as reactors for the preparation of palladium nanoparticles.
Fluorescent nanoaggregates of pentacenequinone derivative serve as reactors for the preparation of palladium nanoparticles in aqueous medium. Further, the combination of catalytic quantities of palla...Read More
p-Aminophenol (PAP) produces nephrotoxicity in rats through a mechanism presumably involving oxidation and conjugation with glutathione (GSH). Recently it was found that PAP also causes nephrotoxicity...Read More
p-Aminophenol (PAP) is a widely used industrial chemical and a metabolite of analgesics, such as acetaminophen (APAP). It was found recently that PAP, a known nephrotoxicant, could cause acute hepatot...Read More
p-Aminophenol (PAP) is a widely used industrial chemical and a known nephrotoxin. Recently, it was found to also cause hepatotoxicity and glutathione (GSH) depletion in mice. The exact mechanism of li...Read More
Nanomolar detection of p-nitrophenol via in situ generation of p-aminophenol at nanostructured microelectrodes.
A new method and a new buffer medium, expected to be practical for miniaturized electrochemical immunoassays, were developed for rapid detection of nanomolar levels of p-nitrophenol (p-NP). The method...Read More
4-Dimethylaminophenol hydrochloride (DMAP), 20mg/kg i.v., was found to oxidize in rats as much as 50% of the hemoglobin to ferrihemoglobin but did not cause kidney lesions. 4-Aminophenol hydrochloride...Read More
Cellular apoptosis and cytotoxicity of phenolic compounds: a quantitative structure-activity relationship study.
In this comprehensive study on the caspase-mediated apoptosis-inducing effect of 51 substituted phenols in a murine leukemia cell line (L1210), we determined the concentrations needed to induce caspas...Read More