展开

6-氨基青霉烷酸

产品编号 A101337 | CAS号 551-16-6 | Aladdin
(+)-6-Aminopenicillanic acid
98%
组合的产品项目
货号 规格 库存 价格 数量
A101337-100g 98% 上海(预计3-7周)
北方(预计3-7周)
 
A101337-25g 98% 上海(6)
北方(3)
 
A101337-5g 98% 上海(8)
北方(预计3-5个工作日)
 
客户看了后又看了下面的产品

属性

密度 1.5200
熔点 198-200°C
存贮条件 储存温度2-8°C

描述

产品介绍 微溶于水,不溶于乙酸丁酯、乙醇或丙酮。遇碱分解,对酸较稳定。
别名 6-氨基青霉烷酸 ;6-氨基青霉素酸,3-二甲基-7-氧代-4-硫杂-1-氮杂二环[3.2.0]庚烷-2-羧酸-6-氨基-3;(2S,5R,6R)-6-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 6-APA 6-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 6-amino-2,2-dimethyl-5-oxoperhydroazeto[2,1-b][1,3]thiazole-3-carboxylic acid
应用 制备半合成青霉素的原料。
编写您自己的评论
只有注册的用户才可以写评论。请 登录 创建帐户
标识符号 GHS08 GHS08
信号词 Danger
风险声明 (欧洲) R42/43;
安全声明(欧洲) S22;S36/37
警示性声明 P261,P280,P342+P311
危害码(欧洲) Xn
危害声明 H317,H334
个人防护设备 dust mask type N95 (US),Eyeshields,Faceshields,Gloves
RTECS XH8225000
WGK德国 2
Merck Index 458
参考文献
Shu-Guang Fang, Tan Qiang, Rui-Jiang Liu, Xi-Ming Xu, Ye-Wang Zhang
Enzymatic hydrolysis of penicillin G for production of 6-amino-penicillanic-acid (6-APA) was achieved by using penicillin G acylase as catalyst in an aqueous-methylisobutyl ketone (MIBK) system. The o...Read More
Joanna Skiba, Aleksandra Rajnisz, Kely Navakoski de Oliveira, Ingo Ott, Jolanta Solecka, Konrad Kowalski
We report on the synthesis of ferrocenyl-ampicillin and ferrocenyl-6-aminopenicillinic acid bioconjugates. Title compounds were characterized by (1)H NMR, IR, MS and elemental analysis. These novel fe...Read More
Francesco Crea, Daniela Cucinotta, Concetta De Stefano, Demetrio Milea, Silvio Sammartano, Giuseppina Vianelli
The total solubility of three penicillin derivatives was determined, in pure water and NaCl aqueous solutions at different salt concentrations (from ~0.15 to 1.0 mol L(-1) for ampicillin and amoxici...Read More
C?t?lina Daniela CD Stan, Alina A Stefanache, Maria M Dr?gan, Antonia A Poiat?, D E DE Diaconu, Lenu?a L Profire
The 6-aminopenicillanic acid acylation with certain acyl chlorides was performed in order to obtain antistaphylococcal penicillins with bigger crystals, easy to filtrate (shorter filtration time), muc...Read More
J-L Schmutz, A Barbaud, P Trechot
We're sorry this abstract is currently not available....Read More
Zhiqiang Chen, Hongcheng Wang, Zhaobo Chen, Nanqi Ren, Aijie Wang, Yue Shi, Xiaoming Li
A full-scale test was conducted with an up-flow anaerobic sludge blanket (UASB) pre-treating pharmaceutical wastewater containing 6-aminopenicillanic acid (6-APA) and amoxicillin. The aim of the study...Read More
Nolwenn N Coquart, Ingrid I Kupfer-Bessaguet, Frédéric F Staroz, Patrice P Plantin
We're sorry this abstract is currently not available....Read More
Ye-Wang Zhang, Rui-Jiang Liu, Xi-Ming Xu
A one-pot, two-step enzymatic synthesis of amoxicillin from penicillin G, using penicillin acylase, is presented. Immobilized penicillin acylase from Kluyvera citrophila was selected as the biocatalys...Read More
J J Swaminathan, M M Ramalingam, V V Sethuraman, N N Sundaraganesan, S S Sebastian, M M Kurt
Quantum mechanical calculations of energies, geometries and vibrational wavenumbers of 6-aminopenicillanic acid were carried out by using ab initio HF and density functional theory (DFT/B3LYP) methods...Read More
José Luis Martínez-Hernández, Marco Arnulfo Mata-Gómez, Cristóbal Noé Aguilar-González, Anna Ilyina
The production of extracellular and mycelia-associated penicillin G acylase (maPGA) with Mucor griseocyanus H/55.1.1 by surface-adhesion fermentation using Opuntia imbricata, a cactus, as a natural im...Read More
Edson Romano Nucci, Antonio J G Cruz, Roberto C Giordano
We're sorry this abstract is currently not available....Read More
David A Harris, Michael E Powers, Floyd E Romesberg
We report the first synthesis of a 5S penem, known to bind bacterial type I signal peptidase, from the commercially available and inexpensive 6-aminopenicillanic acid. We report the first in vivo acti...Read More
Teresa T Jackowska, Katarzyna K Pawlik, Joanna J Za?eska-Ponganis, Magdalena M K?yszewska
the basis of urinary tract infection (UTI) diagnosis in children is based on positive results of microbiological tests. The selection of an antimicrobial drug for empirical treatment and prophylaxis o...Read More
Rubina R Arshad, Shafqat S Farooq, Syed Shahid SS Ali
The present study was conducted to see the difference in production of 6-APA I) between wild strains of E. coli collected from local environment and their acridine orange (AO) induced mutants and ii) ...Read More
Lisa M Bergeron, David L Shis, Lizabeth Gomez, Douglas S Clark
The functionality of regions within the equatorial domain of Group II chaperonins is poorly understood. Previously we showed that a 70 amino acid sequence within this domain on the single-subunit reco...Read More
A T AT Karagulle Kendi, C C Krenzel, F W FW Ott, J R JR Brace, S K SK Norberg, S A SA Kieffer
Isolated bilateral striatal necrosis is an abnormality of the basal ganglia associated with acute dystonia in children. This report describes the development of dystonic movements in a 7-year-old male...Read More
Pak-Ho PH Chan, Pui-Kin PK So, Dik-Lung DL Ma, Yanxiang Y Zhao, Tat-Shing TS Lai, Wai-Hong WH Chung, Kwok-Chu KC Chan, Ka-Fai KF Yiu, Hoi-Wan HW Chan, Fung-Ming FM Siu, Chun-Wai CW Tsang, Yun-Chung YC Leung, Kwok-Yin KY Wong
The fluorescein-labeled E166C mutant of the PenPC beta-lactamase (E166Cf) represents a successful model in the construction of "switch-on" fluorescent biosensors from nonallosteric proteins ...Read More
Chunqiu C Tian, Huarong H Tan, Liping L Gao, Huqin H Shen, Kezong K Qi
A high performance capillary electrophoresis (HPCE) method was developed for the simultaneous determination of penicillin intermediate and penicillins in milk, including 6-amino-penicillanic acid (6-A...Read More
Faridoon, Waleed M WM Hussein, Nazar N Ul Islam, Luke W LW Guddat, Gerhard G Schenk, Ross P RP McGeary
Purple acid phosphatases (PAPs) are binuclear metallohydrolases that have a multitude of biological functions and are found in fungi, bacteria, plants and animals. In mammals, PAP activity is linked w...Read More
V B VB Kurochkina, A V AV Sklyarenko, J E JE Satarova, S V SV Yarotsky
The article deals with experimental determination of ionization constants and solubility for the compounds (target products, initial β-lactams, acylating agents and by-products) involved in enzymatic...Read More
A K AK Dolui, S S Das
In the present study different bacterial samples were isolated from soil of different places of Dibrugarh and screened for biotransformation ability to produce 6-Aminopenicillanic acid. Among ten isol...Read More
Junqi Zhao, Yujun Wang, Guangsheng Luo, Shenlin Zhu
In this study, macro-mesoporous silica spheres were prepared with a micro-device and used as the support for the immobilization of penicillin G acylase (PGA). To measure the enzymatic activity, the si...Read More
Louis Anthony Tony Cox, Douglas A Popken, Jeremy J Mathers
Penicillin and ampicillin drugs are approved for use in food animals in the United States to treat, control, and prevent diseases, and penicillin is approved for use to improve growth rates in pigs an...Read More
Weihua Song, Weisang Chen, William J Cooper, John Greaves, George E Miller
Many pharmaceutical compounds and metabolites are being found in surface and ground waters, indicating their ineffective removal by conventional wastewater treatment technologies. Advanced oxidation/r...Read More
Yangyang Y Jiang, Hansong H Xia, Chen C Guo, Iram I Mahmood, Huizhou H Liu
A dodecane/thermosensitive polymer/water three-liquid-phase system was introduced for enzymatic hydrolysis of penicillin G (Pen G) for 6-aminopenicillanic acid (6-APA). The enzyme was covalently attac...Read More