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α-细辛脑

产品编号 A101552 | CAS号 2883-98-9 | Aladdin
Asarone
99%
组合的产品项目
货号 规格 库存 价格 数量
A101552-1g 99% 上海(预计3-7周)
北方(预计3-7周)
 
A101552-5g 99% 上海(1)
北方(预计3-5个工作日)
 
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属性

密度 1.0280
熔点 57-61°C
沸点 296°C

描述

产品介绍 几乎不溶于水,溶于乙醇、乙醚、冰醋酸、四氯化碳、氯仿、石油醚。
别名 α-细辛脑 ;反式-2,4,5-三甲氧基-1-丙烯苯,alpha-细辛脑;2,4,5-Trimethoxy-1-propenylbenzene alpha-Asarone trans-1,2,4-Trimethoxy-5-(1-propenyl)benzene trans-1-Propenyl-2,4,5-trimethoxybenzene
应用 本品具有止咳、祛痰、平喘、解痉、镇静、抗癫痫、降血脂、利脂等作用,对肺炎双球菌、金黄色葡萄球菌和大肠杆菌的生长有不同程度的抑制作用,并具有一定的抗癌活性。
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标识符号 GHS07 GHS07
信号词 Warning
风险声明 (欧洲) 22
安全声明(欧洲) 22,24/25
危害码(欧洲) Xn
危害声明 H302
个人防护设备 dust mask type N95 (US),Eyeshields,Faceshields,Gloves
RTECS DC2975000
WGK德国 3
参考文献
Xi Zou, Shen-Lin Liu, Jin-Yong Zhou, Jian Wu, Bo-Fan Ling, Rui-Ping Wang
Beta-asarone is one of the main bioactive constituents in traditional Chinese medicine Acorus calamu. Previous studies have shown that it has antifungal and anthelmintic activities. However, little is...Read More
Sreenath Nandakumar, Sasikumar Menon, Sunita Shailajan
β-Asarone (BAS), a phenylpropanoid from Acorus calamus Linn., has shown biological effects in the management of cognitive impairment conditions such as Alzheimer's disease. The present paper des...Read More
Hemant Kumar, Byung-Wook Kim, Soo-Yeol Song, Jun-Soo Kim, In-Su Kim, Young-Sook Kwon, Sushruta Koppula, Dong-Kug Choi
The effect of α-asarone on impairment of cognitive performance caused by amnesic drug scopolamine was investigated. Treatment with α-asarone attenuated scopolamine-induced cognitive deficits as eval...Read More
Zhen-tao ZT Mo, Yong-qi YQ Fang, Yu-ping YP He, Sheng S Zhang
To explore the effects of β-asarone from Acorus Tatarinowii Schott on autophagy in an ischemic stroke model of PC12 cells....Read More
Yong-Qi YQ Fang, Chen C Shi, Lin L Liu, Ruo-Ming RM Fang
beta-Asarone has significant pharmacological effects on the central nervous system. As a potential therapeutic agent to manage brain diseases, analysis of the pharmacokinetics of beta-asarone in brain...Read More
Lin L Liu, Yong-Qi YQ Fang, Zhong-Feng ZF Xue, Yu-Ping YP He, Ruo-Ming RM Fang, Ling L Li
Beta-asarone has significant pharmacological effects on the central nervous system. It can attenuate neuronal apoptosis, but its effects on the brain ischemia-reperfusion-induced autophagy have not be...Read More
Chunjuan Ren, Tao Gong, Xun Sun, Zhirong Zhang, Yan Zhang
Alpha-Asarone is clinically used as a commercial intravenous formulation (CA-AREs). However, Polysorbate 80, a solubilizing agent contained in the formulation has been reported to be toxic. To enhance...Read More
Daijie D Wang, Yanling Y Geng, Lei L Fang, Xikai X Shu, Jianhua J Liu, Xiao X Wang, Luqi L Huang
In this study, supercritical fluid extraction (SFE) was used to extract essential oil from Acorus tatarinowii Schott under the pressure of 25 MPa and temperature of 35°C. Two (E)- and (Z)-diastereome...Read More
Cheol Hyeong CH Park, Ki Hyun KH Kim, Il Kyun IK Lee, Seung Young SY Lee, Sang Un SU Choi, Jei Hyun JH Lee, Kang Ro KR Lee
The purification of a MeOH extract from the rhizome of Acorus gramineus (Araceae) using column chromatography furnished two new stereoisomers of phenylpropanoid, acoraminol A (1) and acoraimol B (2). ...Read More
Dongying Qiu, Lili Hou, Yonghua Chen, Xujiao Zhou, Wenjun Yuan, Weifang Rong, Lei Zhu, Jijiang Wang
Therapeutic application of Asarum, a herbal medicine that has been used for centuries, reportedly causes acute respiratory disturbance. The responsible constituents, the sites of action, and the mecha...Read More
De-Jia DJ Zou, Gang G Wang, Ji-Cheng JC Liu, Miao-Xian MX Dong, Xiao-Ming XM Li, Chun C Zhang, Li L Zhou, Rui R Wang, Ying-Cai YC Niu
Beta-amyloid (Abeta) toxicity has been postulated to initiate synaptic loss and subsequent neuronal degeneration seen in Alzheimer's disease (AD). We previously demonstrated that beta-asarone imp...Read More
Ying Hu, Yao-Yao Wu, Xiao-Jing Xia, Zheng Wu, Wen-Quan Liang, Jian-Qing Gao
A transdermal drug delivery system has been reported that can increase the bioavailability, reduce the administration duration, and maintain the concentration of drug in blood. In the present study, d...Read More
Jadwiga Marczewska, Ewa Drozd, Elzbieta Anuszewska, Zdzis?aw Chilmonczyk, Bozena ?ozowicka
In our previous paper we examined mutagenic and genotoxic activity of 4 alpha-asarone isomers 2-5 exhibiting relatively high hypolipidemic activity. In the present paper, we examined genotoxic activit...Read More
Zhenwei Yu, Yi Liang, Wenquan Liang
A hot-melt, pressure-sensitive adhesive (HMPSA) based on styrene-isoprene-styrene was prepared, and its compatibility with various transdermal penetration enhancers was investigated. The effect of pen...Read More
Sandeep B Rajput, S Mohan Karuppayil
Anti-Candida potential of Acorus calamus rhizome and its active principle, β-asarone, was evaluated against the human fungal pathogen, Candida albicans. β-Asarone exhibited promising growth inhibito...Read More
Qi-Xiong Chen, Jing-Kun Miao, Chun Li, Xiao-Wen Li, Xiao-Mei Wu, Xiao-Ping Zhang
For centuries, extracts of Acorus gramineus have been used extensively in traditional Chinese medicine for the treatment, management, and/or control of human ailments, including central nervous system...Read More
Zhiqiang Z Li, Guoping G Zhao, Sanqi S Qian, Zijun Z Yang, Xiaoyin X Chen, Jia J Chen, Chuan C Cai, Xuebing X Liang, Jun J Guo
Recent studies have suggested that β-asarone have neuroprotective and cardiovascular protective effects in animal model. However, the influence of β-asarone on cerebrovascular system has not been ex...Read More
Zhenwei Z Yu, Yi Y Liang, Wenquan W Liang
To investigate the relationship of properties and drug release rate of hot melt pressure sensitive adhesive (HMPSA), and to provide a recommendation of preparing and selecting of HMPSA for transdermal...Read More
Shuang Liu, Si Wei Chen, Na Xu, Xing Hua Liu, Hua Zhang, Yan Zi Wang, Xiao Dan Xu
The effects of α-asarone in four assays predictive of anxiolytic activity in male mice were studied, with diazepam as a positive anxiolytic control. The use of the elevated plus-maze test revealed th...Read More
Mehdi M Mohammadi, Mahdieh M Ghavidel, Zohreh Z Habibi, Mohammad Ali MA As'habi
The chemical composition of the essential oil of Haussknechtia elymaitica Boiss. was investigated by capillary GC and GC/MS for the first time. Twelve components were identified which accounting for 9...Read More
Deepa D Bisht, Anirban A Pal, C S CS Chanotiya, Dhirendra D Mishra, K N KN Pandey
Hydro-distilled essential oils extracted from three commercially important aromatic plants were analysed by capillary gas chromatography-flame ionization detector and gas chromatography/quadrupole mas...Read More
Divyasree Sandeep, Cherupally Krishnan Krishnan Nair
@a-Asarone (1-propenyl-2,4,5-methoxybenzol), one of the active components of Acorus calamus extract, was examined for its efficacy as a radioprotector in mice exposed to lethal and sublethal whole-bod...Read More
Subrata S Pandit, Pulok K PK Mukherjee, Sivasankaran S Ponnusankar, Murugan M Venkatesh, N N Srikanth
The present study was aimed to investigate the possible interaction of the standardized extract of Acorus calamus (AC) with Cytochrome P450 enzyme, quantitative determination of the @a-asarone in the ...Read More