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穿心莲内酯

¥ 148.00

产品编号 A101649 | CAS号 5508-58-7 | Aladdin
Andrographolide
98%
组合的产品项目
货号 规格 库存 价格 数量
A101649-100mg 98% 上海(4)
北方(预计3-5个工作日)
 
A101649-1g 98% 上海(>10)
北方(预计3-5个工作日)
 
A101649-500mg 98% 上海(3)
北方(预计3-5个工作日)
 
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属性

密度 1.2100
熔点 229-232°C

描述

别名 穿心莲内酯 ;穿心莲;
应用 植物抗菌制剂。具有抗炎特性的二萜内酯。它阻止T细胞对异体刺激带来的增殖和巨噬细胞趋化补体迁移。阻止几种癌症细胞在体外的增殖。异体刺激
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安全声明(欧洲) 22,24/25
个人防护设备 Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter
RTECS LU3490750
WGK德国 3
参考文献
Shao-Ying Hu, Zhen-Hai Zhang, Xiao-Bin Jia
To prepare andrographolide solid dispersion, with hydroxyapatite as vector, in order to increase drug dissolution.Andrographolide and hydroxyapatite were dispersed in 95% ethanol. The solvent evaporat...Read More
R Krithika, Rj Verma, Ps Shrivastav
This article describes antioxidative and cytoprotective property of andrographolide, a major active component of the plant Andrographis paniculata (A. paniculata). High yields (2.7%) of andrographolid...Read More
Harrison J Hocker, Kwang-Jin Cho, Chung-Ying K Chen, Nandini Rambahal, Sreenivasa Rao Sagineedu, Khozirah Shaari, Johnson Stanslas, John F Hancock, Alemayehu A Gorfe
Aberrant signaling by oncogenic mutant rat sarcoma (Ras) proteins occurs in ~15% of all human tumors, yet direct inhibition of Ras by small molecules has remained elusive. Recently, several small-mo...Read More
X P Li, C L Zhang, P Gao, J Gao, D Liu
Andrographolide, which is one of the main pharmaceutical ingredients in traditional Chinese medicine Andrographis paniculata, can clear heat, detoxify human body, cool blood and reduce swelling, etc. ...Read More
Zhong Rong Zhang, Mazen Al Zaharna, Matthew Man-Kin Wong, Sung-Kay Chiu, Hon-Yeung Cheung
Andrographolide (Andro) suppresses proliferation and triggers apoptosis in many types of cancer cells. Taxifolin (Taxi) has been proposed to prevent cancer development similar to other dietary flavono...Read More
S Manoharan, Arjun Kumar Singh, K Suresh, K Vasudevan, R Subhasini, N Baskaran
The aim of the study was to investigate the chemopreventive potential of andrographolide in 7,12-dimethylbenz(a) anthracene (DMBA)-induced hamster buccal pouch carcinogenesis. Oral tumors developed in...Read More
Yong-Yang Zhu, Guangchuang Yu, Ye Zhang, Zheng Xu, Yu-Qiang Wang, Guang-Rong Yan, Qing-Yu He
Andrographolide-lipoic acid conjugate (AL-1) is a new in-house synthesized chemical entity, which was derived by covalently linking andrographolide with lipoic acid. However, its anti-cancer effect an...Read More
Yan Y Guan, Jiuyun J Zhang, Changzhong C Wang, Ning N Wang, Zhifang Z Liu, Jingjin J Shi
To provide a new therapeutic approach for Staphylococcus epidermidis biofilm-associated infections by the study of inhibitory effect of andrographolide (AG) on S. epidermidis biofilm....Read More
Partha Roy, Suvadra Das, Anushree Mondal, Urmi Chatterji, Arup Mukherjee
Success in cancer chemotherapy relies on efficient delivery of anti-neoplastic drugs, with minimal side-effects on non-cancerous cells. Nanoparticulation of prospective anti-cancer drugs, that were de...Read More
Myra T W Cheung, Rajkumar Ramalingam, Kenneth K K Lau, W L Chiang, S K Chiu
We're sorry this abstract is currently not available....Read More
Wenjie Guo, Wen Liu, Gong Chen, Shaocheng Hong, Cheng Qian, Ning Xie, Xiaoling Yang, Yang Sun, Qiang Xu
Andrographolide is a prescribed drug used for preventing and treating the common cold, influenza, viral infections or allergies. However, its poor water solubility enormously limits its bioavailabilit...Read More
Shuang-Qing Zhang, Yu-Ming Fan
A sensitive and reliable liquid chromatography-tandem mass spectrometry (LC-MS/MS) has been developed and validated for the determination of andrographolide sodium bisulphite (ASB) in dog plasma using...Read More
Suryakala Gandi, Kiranmayee Rao, Bhuvaneswari Chodisetti, Archana Giri
Andrographis paniculata belonging to the family Acanthaceae produces a group of diterpene lactones, one of which is the pharmaceutically important-andrographolide. It is known to possess various impor...Read More
Yonglei Yuan, Long Ji, Liping Luo, Juan Lu, Xiaoqiong Ma, Zhongjun Ma, Zhe Chen
In the present study, it was demonstrated that the petroleum extract of Andrographis paniculata (AP) had quinone reductase (QR) inducing activity, which might be attributed to the modification of key ...Read More
Wei Chen, Lina Feng, Hao Nie, Xiaodong Zheng
Liver cancer is the third leading cause of cancer death worldwide and about half of the patients with liver cancer require adjuvant therapy after surgical resection. Therefore, development of novel ag...Read More
S Kumar, H S Patil, P Sharma, D Kumar, S Dasari, V G Puranik, H V Thulasiram, G C Kundu
Breast cancer is one of the most common cancers among women in India and around the world. Despite recent advancement in the treatment of breast cancer, the results of chemotherapy to date remain unsa...Read More
Tao Yang, Hai-xia Shi, Zheng-tao Wang, Chang-hong Wang
Andrographolide (AND) and neoandrographolide (NEO) are the diterpenoids from the Andrographis paniculata (Acanthaceae). It is reported the diterpenoids exhibit a wide spectrum of biological activities...Read More
V K VK Kibirev, T V TV Osadchuk
This review is devoted to structure and properties of proprotein convertases (PCs), the intracellular Ca(2+)-dependent serine endoproteases of mammalia, that play the essential role in the processing ...Read More
Bin Zhou, Dayong Zhang, Xiaoming Wu
In recent years, pharmaceutical chemists have synthesized large numbers of andrographolide derivatives, which bear important biological activities such as anti-inflammatory, antibacterial, antivirus, ...Read More
Tao Zhu, Dao-Xin Wang, Wei Zhang, Xiu-Qing Liao, Xian Guan, Hong Bo, Jia-Yang Sun, Ni-Wen Huang, Jing He, Yun-Kun Zhang, Jing Tong, Chang-Yi Li
Nuclear factor-κB (NF-κB) is a central transcriptional factor and a pleiotropic regulator of many genes involved in acute lung injury. Andrographolide is found in the plant of Andrographis paniculat...Read More
Sun-Wei Guo, Xiaoyan Mao, Qingliang Ma, Xishi Liu
To evaluate uterine contractility, oxytocin receptor (OTR) expression in myometrial smooth muscle cells (MSMCs) derived from uterine tissues from women with and without adenomyosis correlate OTR expre...Read More
Qi Zhao, Jie Ding, Haiyan Jin, Lan Ding, Nanqi Ren
A method based on cloud point extraction (CPE) coupled with high-performance liquid chromatography separation and ultraviolet (UV) detection was developed to determine andrographolide and dehydroandro...Read More
Mayur M Uttekar, Tiyasa Das, Rohan S Pawar, Beena Bhandari, Vidya Menon, Vidya Menon, Satish K Gupta, Sujata V Bhat
Andrographolide, a diterpene lactone of the Andrographis paniculata, displays anti-HIV activity in vitro. A series of andrographolide derivatives have been synthesized and evaluated for their anti-HIV...Read More
Wan J WJ Lu, Kuan H KH Lin, Ming J MJ Hsu, Duen S DS Chou, George G Hsiao, Joen R JR Sheu
Andrographolide, a novel nuclear factor-κB (NF-κB) inhibitor, is isolated from leaves of Andrographis paniculata. Platelet activation is relevant to a variety of coronary heart diseases. Our recent ...Read More
Minghua Yang, Junsong Wang, Lingyi Kong
A quantitative proton nuclear magnetic resonance technique (qHNMR) has been successfully introduced to quantify andrographolide, dehydroandrographolide, deoxyandrographolide and neoandrographolide in ...Read More
Mirentxu I MI Iruretagoyena, Jaime A JA Tobar, Pablo A PA González, Sofía E SE Sepúlveda, Claudio A CA Figueroa, Rafael A RA Burgos, Juan L JL Hancke, Alexis M AM Kalergis
Andrographolide is a bicyclic diterpenoid lactone derived from extracts of Andrographis paniculata, a plant indigenous to South Asian countries that shows anti-inflammatory properties. The molecular a...Read More
Hwei-Ru Tsai, Li-Ming Yang, Wei-Jern Tsai, Wen-Fei Chiou
We now evaluated the anti-inflammatory mechanisms of andrographolide on complement 5a (C5a)-induced macrophage recruitment in vitro. Andrographolide concentration dependently inhibited cell migration ...Read More
Yi-Feng Xia, Bu-Qing Ye, Yi-Dan Li, Jian-Guo Wang, Xiang-Jiu He, Xianfeng Lin, Xinsheng Yao, Dawei Ma, Arne Slungaard, Robert P Hebbel, Nigel S Key, Jian-Guo Geng
NF-kappaB is a central transcriptional factor and a pleiotropic regulator of many genes involved in immunological responses. During the screening of a plant extract library of traditional Chinese herb...Read More
Jiun-Han JH Chen, George G Hsiao, An-Rong AR Lee, Chin-Chen CC Wu, Mao-Hsiung MH Yen
Andrographolide (Andro), an active component isolated from the Chinese official herbal Andrographis paniculata, which has been reported to prevent oxygen radical production and thus prevent inflammato...Read More
Sriram S Rajagopal, R Ajaya RA Kumar, Dhanvanthri S DS Deevi, Chitkala C Satyanarayana, R R Rajagopalan
Andrographis paniculata plant extract is known to possess a variety of pharmacological activities. Andrographolide, the major constituent of the extract is implicated towards its pharmacological activ...Read More