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Arg-Gly-Asp-Ser

产品编号 A101721 | CAS号 91037-65-9 | Aladdin
Arg-Gly-Asp-Ser
≥95%(HPLC)
组合的产品项目
货号 规格 库存 价格 数量
A101721-25mg ≥95%(HPLC) 上海(预计3-7周)
北方(预计3-7周)
 
A101721-2mg ≥95%(HPLC) 上海(预计3-7周)
北方(预计3-7周)
 
A101721-5mg ≥95%(HPLC) 上海(4)
北方(预计3-5个工作日)
 
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属性

密度 1.6500
存贮条件 储存温度-20°C

描述

应用 四肽,支持成纤维细胞(fibroblast)附着和抑制纤维连接蛋白(fibronectin)结合到血小板上。靶序列用于梅毒螺旋体(syphilis spirochete)粘附
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个人防护设备 Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter
WGK德国 3
参考文献
S S Sambu, X X Xu, H A HA Schiffer, Z F ZF Cui, H H Ye
Cryopreservation of stem cells, especially embryonic stem cells, is problematic because of low post-thaw cell survival rates and spontaneous differentiation following recovery. In this investigation, ...Read More
M D MD Pierschbacher, E E Ruoslahti
The ability of fibronectin to bind cells can be accounted for by the tetrapeptide L-arginyl-glycyl-L-aspartyl-L-serine, a sequence which is part of the cell attachment domain of fibronectin and presen...Read More
R R Ortega-Velázquez, M L ML Díez-Marqués, M P MP Ruiz-Torres, M M González-Rubio, M M Rodríguez-Puyol, D D Rodríguez Puyol
Extracellular matrix (ECM) components, through specific peptide motifs such as Arg-Gly-Asp (RGD), interact with integrins and can modify the behavior of cells. Transforming growth factor-beta1 (TGF-be...Read More
W W Wimmer, S S Perovic, M M Kruse, H C HC Schr?der, A A Krasko, R R Batel, W E WE Müller
Sponges (phylum Porifera) represent the phylogenetically oldest metazoan animals. Recently, from the marine sponge Geodia cydonium a first cDNA encoding a putative integrin receptor molecule was isola...Read More
Rajamouli Pasula, Paul Wisniowski, William J Martin
Mycobacterium tuberculosis remains a major cause of pulmonary infection worldwide. Attachment of M. tuberculosis organisms to alveolar macrophages (AMs) represents the earliest phase of primary infect...Read More
Tjitske A Oenema, Gerrianne Mensink, Lyanne Smedinga, Andrew J Halayko, Johan Zaagsma, Herman Meurs, Reinoud Gosens, Bart G J Dekkers
Transforming growth factor-β1 (TGF-β1) is a central mediator in tissue remodeling processes, including fibrosis and airway smooth muscle (ASM) hyperplasia, as observed in asthma. The mechanisms unde...Read More
Shivanjali Joshi-Barr, Jerome V Karpiak, Yogesh Ner, Jessica H Wen, Adam J Engler, Adah Almutairi
Complex tissue culture matrices, in which types and concentrations of biological stimuli (e.g. growth factors, inhibitors, or small molecules) or matrix structure (e.g. composition, concentration, or ...Read More
Catherine A Goubko, Ajoy Basak, Swapan Majumdar, Harold Jarrell, Nam Huan Khieu, Xudong Cao
Photocaged RGDS is a cell nonadhesive tetrapeptide that can be activated with light to become cell-adhesive. Such molecules can find useful applications in controlling cell adhesion for biological stu...Read More
Caner Nazli, Tugba Ipek Ergenc, Yasemin Yar, Havva Yagci Acar, Seda Kizilel
The objective of this study was to develop thin, biocompatible, and biofunctional hydrogel-coated small-sized nanoparticles that exhibit favorable stability, viability, and specific cellular uptake. T...Read More
Bin B Wang, Jing-Yuan JY Wan, Li L Zhang, Su S Min
Pulmonary inflammation is the key pathological presentation of mechanical ventilation-induced lung injury (VILI), and synthetic RGDS peptide has been suggested to attenuate pulmonary inflammation. The...Read More
Maria Simona Aguzzi, Daniela D'Arcangelo, Claudia Giampietri, Maurizio C Capogrossi, Antonio Facchiano
Peptides containing the RGD sequence are under continuous investigation given their ability to control cell adhesion and apoptosis. Since small peptides are quickly metabolized and degraded in vivo, d...Read More
A M AM Porter, C M CM Klinge, A S AS Gobin
Angiogenesis is an important biological response known to be involved in many physiological and pathophysiological situations. Cellular responses involved in the formation of new blood vessels, such a...Read More
Nan Cheng, Xudong Cao
An approach to control cell adhesion using a photocleavable molecule on chitosan has been developed and studied. Photocleavable 4,5-dimethoxy-2-nitrobenzyl chloroformate (NVOC) was introduced into chi...Read More
Maria Grazia MG Signorello, Enrica E Giacobbe, Giuliana G Leoncini
The endogenous cannabinoid 2-arachidonoylglycerol (2-AG) is described as a platelet agonist able to induce aggregation and to increase intracellular calcium. In the present report we have confirmed th...Read More
J S Stephens-Altus, P Sundelacruz, M L Rowland, J L West
Three-dimensional (3D) fibrous hydrogels were fabricated by blending two photoactive polymers, poly(ethylene glycol) diacrylate (PEGDA) and poly(vinyl alcohol) (PVA), and the resulting solution was el...Read More
Chien-Chi Lin, Kristi S Anseth
A biomimetic hydrogel platform was designed to signal encapsulated cells using immobilized cell-cell communication cues, with a focus on enhancing the survival and function of encapsulated pancreatic ...Read More
Yusuke Kambe, Yuji Takeda, Koji Yamamoto, Katsura Kojima, Yasushi Tamada, Naohide Tomita
Initial chondrocyte-material interactions are important for cell behaviors such as proliferation, phenotypic expression and matrix synthesis. Previously, we showed that chondrocytes cultured in/on sil...Read More
Sapun H Parekh, Kaushik Chatterjee, Sheng Lin-Gibson, Nicole M Moore, Marcus T Cicerone, Marian F Young, Carl G Simon
Proliferation and differentiation of cells are known to be influenced by the physical properties of the extracellular environment. Previous studies examining biophysics underlying cell response to mat...Read More
Yasuhiko Y Abe, Yohei Y Okazaki, Kyou K Hiasa, Isao I Hirata, Yasuhiro Y Yoshida, Tsuyoshi T Taji, Kazuomi K Suzuki, Masayuki M Okazaki, Yasumasa Y Akagawa
The purpose of this study was to characterize the chemical interaction between titanium surfaces and the peptide RGDS(PO(3)H(2))PA (P-RGD) synthesized from RGD peptide (RGD) and o-phospho-L-serine (P-...Read More
Z Huang, C J Newcomb, Y Zhou, Y P Lei, P Bringas, S I Stupp, M L Snead
Enamel formation involves highly orchestrated intracellular and extracellular events; following development, the tissue is unable to regenerate, making it a challenging target for tissue engineering. ...Read More
Céline Chollet, Reine Bareille, Murielle Rémy, Alain Guignandon, Laurence Bordenave, Gaetan Laroche, Marie-Christine Durrieu
HSVEC behavior under physiological shear stress in vitro is investigated on PET surfaces micropatterned with both RGDS and WQPPRARI peptides. This technique allows (i) creating geometries on surface t...Read More
Bartley J Gill, Don L Gibbons, Laila C Roudsari, Jennifer E Saik, Zain H Rizvi, Jonathon D Roybal, Jonathan M Kurie, Jennifer L West
Better understanding of the biophysical and biochemical cues of the tumor extracellular matrix environment that influence metastasis may have important implications for new cancer therapeutics. Initia...Read More
Lian L Leng, Arianna A McAllister, Boyang B Zhang, Milica M Radisic, Axel A Günther
The one-step, continuous formation of mosaic hydrogel sheets is presented. A microfluidic device allows controllable incorporation of secondary biopolymers within a flowing biopolymer sheet followed b...Read More
Y Y Aoki, D D Qiu, G H GH Zhao, P N PN Kao
There is increasing interest in the role of infections in atherothrombotic conditions. In particular, bacteria, notably those of oral origin, have been shown to activate platelets using a variety of m...Read More
Toshiki T Sawada, Hisakazu H Mihara
We obtained novel peptides that selectively bind to self-assembling peptide nanomaterials from a random peptide library displayed on phages. Affinity-dependent peptide screening gave phage clones disp...Read More
Esther E Tejeda-Montes, Katherine H KH Smith, Marta M Poch, María Jesús MJ López-Bosque, Laura L Martín, Matilde M Alonso, Elisabeth E Engel, Alvaro A Mata
We report on the combination of a top-down and bottom-up approach to develop thin bioactive membrane scaffolds based on functional elastin-like polymers (ELPs). Our strategy combines ELP cross-linking...Read More
Valeria S VS Mouguelar, Marcelo O MO Cabada, Gabriela G Coux
Integrins are cell adhesion molecules that are thought to be involved in sperm-oocyte interaction. Nevertheless, their function in mammalian fertilization is still controversial, as different species ...Read More
Jangwook P Jung, José V Moyano, Joel H Collier
Extracellular matrices (ECMs) are complex materials, containing at least dozens of different macromolecules that are assembled together, thus complicating their optimization towards applications in 3D...Read More