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精氨酰-甘氨酰-天冬氨酸

产品编号 A101724 | CAS号 99896-85-2 | Aladdin
Arg-Gly-Asp
≥97% (HPLC)
组合的产品项目
货号 规格 库存 价格 数量
A101724-10mg ≥97% (HPLC) 上海(>10)
北方(预计3-5个工作日)
 
A101724-1mg ≥97% (HPLC) 上海(>10)
北方(预计3-5个工作日)
 
A101724-25mg ≥97% (HPLC) 上海(1)
北方(预计3-5个工作日)
 
A101724-5mg ≥97% (HPLC) 上海(>10)
北方(预计3-5个工作日)
 
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属性

密度 1.6100
存贮条件 储存温度-20°C

描述

产品介绍 三肽,来自于纤维细胞附着域 氨基酸序列 Arg-Gly-Asp
别名 RGD;RGD
生化机理 Primary sequence involved with the binding of proteins to cell surfaces
备注 Tripeptide from the cell-attachment domain of fibronectin
应用 涉及结合到细胞表面蛋白质的首选序列
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个人防护设备 Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter
WGK德国 3
参考文献
Pauline Neirynck, Jenny Brinkmann, Qi An, Daisy W J van der Schaft, Lech-Gustav Milroy, Pascal Jonkheijm, Luc Brunsveld
Supramolecular control of adhesion of cells is demonstrated using synthetic integrin binding RGD peptide-ferrocene conjugates that were immobilized via host-guest chemistry onto cucurbit[7]uril coated...Read More
Xiao-Bin Hou, Yong-Cheng Hu, Jin-Quan He
To investigate the feasibility of determining the surface density of arginine-glycine-aspartic acid (RGD) peptides grafted onto allogeneic bone by an isotopic tracing method involving labeling these p...Read More
Erin J Sheridan, Christopher J D Austin, Jade B Aitken, Stefan Vogt, Katrina A Jolliffe, Hugh H Harris, Louis M Rendina
The first example of synchrotron X-ray fluorescence imaging of cultured mammalian cells in cyclic peptide research is reported. The study reports the first quantitative analysis of the incorporation o...Read More
K P KP Yip, D J DJ Marsh
The potential role of integrins in the myogenic mechanism was studied in the rat afferent arteriole (AA) by fluorescence immunolocalization and microperfusion of isolated AA. Confocal fluorescence ima...Read More
J J Reed, W E WE Hull, C W CW von der Lieth, D D Kübler, S S Suhai, V V Kinzel
The primary sequence Arg-Gly-Asp has been found in a number of proteins which bind to cell surface receptors. Studies with synthetic peptides have shown that the presence of charged side chains alone ...Read More
A Krause, W Z Whu, J Qiu, D Wafadari, N R Hackett, A Sharma, R G Crystal, S Worgall
Replication-deficient adenoviral (Ad) vectors of non-human serotypes can serve as Ad vaccine platforms to circumvent pre-existing anti-human Ad immunity. We found previously that, in addition to that ...Read More
Weixing Wan, Ning Guo, Donghui Pan, Chunjing Yu, Yuan Weng, Shineng Luo, Hong Ding, Yuping Xu, Lizhen Wang, Lixin Lang, Qingguo Xie, Min Yang, Xiaoyuan Chen
(18)F-FPPRGD2, which was approved for clinical study recently, has favorable properties for integrin targeting and showed potential for antiangiogenic therapy and early response monitoring. However, t...Read More
Susanna Sartori, Andrea Caporale, Alfonsina Rechichi, Domenico Cufari, Caterina Cristallini, Niccoletta Barbani, Paolo Giusti, Gianluca Ciardelli
This study covers the preparation of microspheres for the controlled and targeted release of paclitaxel, using novel degradable polymers as carrier materials. Paclitaxel-loaded microspheres were prepa...Read More
Yimei Lu, Yiling Zhong, Jie Wang, Yuanyuan Su, Fei Peng, Yanfeng Zhou, Xiangxu Jiang, Yao He
Over the past two decades, fluorescent quantum dots (QDs) have been highly attractive for a myriad of bioapplications due to their unique optical properties. For bioimaging applications, QD-based in v...Read More
Jonathan Lam, Tatiana Segura
Biomaterials designed to mimic the intricate native extracellular matrix (ECM) can use a variety of techniques to control the behavior of encapsulated cells. Common methods include controlling the mec...Read More
Sweety Mittal, Mohini Bhadwal, Sudipta Chakraborty, H D Sarma, Sharmila Banerjee, M R A Pillai
Radiolabeled Arg-Gly-Asp (RGD) peptides are promising agents for non invasive imaging of αβ expression in malignant tumors. The integrin αβ binding affinity and consequent tumor uptake could be im...Read More
Jianglin Wang, Lin Wang, Xin Li, Chuanbin Mao
Biochemical and topographical features of an artificial extracellular matrix (aECM) can direct stem cell fate. However, it is difficult to vary only the biochemical cues without changing nanotopograph...Read More
Jérémie Silvent, Jean-Yves Sire, Sidney Delgado
Dentin matrix acidic phosphoprotein 1 (DMP1) is an acidic, highly phosphorylated, noncollagenous protein secreted during dentin and bone formation. Previous functional studies of DMP1 have revealed va...Read More
Xuan Wang, Ce Yan, Kai Ye, Yao He, Zhenhua Li, Jiandong Ding
Nanopatterns of a cell-adhesive peptide arginine-glycine-aspartate (RGD) on a persistently non-fouling poly(ethylene glycol) hydrogel were prepared, and behaviours of mesenchymal stem cells (MSCs) on ...Read More
Stijn F M van Dongen, Paolo Maiuri, Emmanuelle Marie, Christophe Tribet, Matthieu Piel
There's an APP for that: cell-repellent APP (azido-[polylysine-g-PEG]) is used to create substrates for spatially controlled dynamic cell adhesion. The simple addition of a functional peptide to ...Read More
Li-Yang Jiang, Bing Lv, Ying Luo
By presenting biomolecular ligands on the surface in high density, ligand-decorated dendrimers are capable of binding to membrane receptors and cells with specificity and avidity. Despite the various ...Read More
S Ke, W Wang, X Qiu, F Zhang, J T Yustein, A G Cameron, S Zhang, D Yu, C Zou, X Gao, J Lin, S Yallampalli, M Li
Breast cancer is a heterogenetic tumor at the cellular level with multiple factors and components. The inconsistent expression of molecular markers during disease progression reduces the accuracy of d...Read More
Yuqin Wang, Zhaoliang Zhang, Lu Xu, Xingyi Li, Hao Chen
Molecular hydrogels formed by Fmoc-short peptides have been demonstrated to be a class of promising scaffolds/carrier for in vitro cell cultures/drug delivery. In this paper, we firstly studied the ge...Read More
Hua-feng Zhang, Zhi-jun Li, Xin Fu, Jian-xiong Ma, Xin-long Ma
Acellular bone matrix (ACM) is a promising biodegradable material scaffold. However, poor cell attachment properties of ACM limit its application. This study investigated the biocompatibility of mesen...Read More
Christian H Bell, Eleanor Healey, Susan van Erp, Benjamin Bishop, Chenxiang Tang, Robert J C Gilbert, A Radu Aricescu, R Jeroen Pasterkamp, Christian Siebold
Repulsive guidance molecule family members (RGMs) control fundamental and diverse cellular processes, including motility and adhesion, immune cell regulation, and systemic iron metabolism. However, it...Read More
Eon Jeong Nam, Jin Hee Kang, Shijin Sung, Keum Hee Sa, Kyung Hoon Kim, Jae Seok Seo, Jong-Ho Kim, Seung Woo Han, In San Kim, Young Mo Kang
Transforming growth factor β-inducible gene h3 (βIG-H3), which is abundantly expressed in rheumatoid synovium, and matrix metalloproteinases (MMP) play important roles in the pathogenesis of rheumat...Read More
Milene Kong, Nicolás Mu?oz, Alejandra Valdivia, Alvaro Alvarez, Rodrigo Herrera-Molina, Areli Cárdenas, Pascal Schneider, Keith Burridge, Andrew F G Quest, Lisette Leyton
Cell adhesion to the extracellular matrix proteins occurs through interactions with integrins that bind to Arg-Gly-Asp (RGD) tripeptides, and syndecan-4, which recognizes the heparin-binding domain of...Read More
Jorge Almodóvar, Thomas Crouzier, ?eila Selimovi?, Thomas Boudou, Ali Khademhosseini, Catherine Picart
The cell microenvironment is a complex and anisotropic matrix composed of a number of physical and biochemical cues that control cellular processes. A current challenge in biomaterials is the engineer...Read More
Hao Wu, Deborah Downs, Koena Ghosh, Arun K Ghosh, Peter Staib, Michel Monod, Jordan Tang
Systemic infection by the pathogenic yeast Candida albicans produces high mortality in immune-compromised people. Such infection starts with the penetration of the organism at the mucosal surfaces, fa...Read More
Amir Abbas Mokhtarieh, Semi Kim, Yunhee Lee, Bong Hyun Chung, Myung Kyu Lee
Cell penetrating peptides (CPPs) have been used to transport macromolecules into cells. Most CPPs have properties such as a strong polycationic charge, amphipathic basic, and hydrophobicity. In this s...Read More
James J Cody, Angel A Rivera, Gray R Lyons, Sherry W Yang, Minghui Wang, Jason W Ashley, Sreelatha Meleth, Xu Feng, Gene P Siegal, Joanne T Douglas
Metastatic involvement of the skeleton is a frequent consequence of advanced prostate cancer. These skeletal metastases cause a number of debilitating complications and are refractory to current treat...Read More
Elena Ranyuk, Nicole Cauchon, Klaus Klarskov, Brigitte Guérin, Johan E van Lier
The synthesis of a series of new zinc phthalocyanine-peptide conjugates targeting the gastrin-releasing peptide (GRP) and integrin receptors is reported. Two alternative synthetic methods based on Son...Read More
Johannes Winkler
Insufficient pharmacokinetic properties and poor cellular uptake are the main hurdles for successful therapeutic development of oligonucleotide agents. The covalent attachment of various ligands desig...Read More
Hongyan Ge, Pei Tian, Linan Guan, Xiuli Yin, Hanruo Liu, Nan Xiao, Yongzhong Xiong, Xin Luo, Yunduan Sun, Donghua Qi, Shuang Ni, Ping Liu
An Arg-Gly-Asp (RGD) motif in the fourth FAS1 domain of the human BIGH3 (transforming growth factor-β1-inducible gene-h3) protein has been reported to play an important role in mediating tumor angiog...Read More
Zhe Yang, Xingen Luo, Xiaofang Zhang, Jie Liu, Qing Jiang
Lipid-polymer hybrid nanoparticles (NPs) combining the positive attributes of both liposomes and polymeric NPs are increasingly being considered as promising candidates to carry therapeutic agents saf...Read More