|产品介绍||Soluble in methanol (20 mg/ml clear, faint yellow solution), ethanol (25 mg/ml), DMSO (50 mg/ml), alcohols, esters, ketones, chloroform, benzene (slightly), toluene (slightly), hexane (slightly), water (2 mg/ml), and ethyl acetate (10 mg/ml clear, colorless solution), DMF (20 mg/ml), and PBS pH 7.2 (0.5 mg/ml).|
|别名||(2R,3S,4S)-2-(4-甲氧苯基)-3,4-吡咯二醇 3-乙酸酯;(2R,3S,4S)-2-(4-Methoxybenzyl)-3,4-pyrrolidinediol-3-acetate; 2-[(4-Methoxyphenyl)methyl]-3,4-pyrrolidinediol 3-acetate; Flagecidin|
|生化机理||从Streptomyces griseolus 分离的抗生素，抑制蛋白质合成。通过抑制真核生物核糖体肽基转移酶的活性而发挥作用。据报道，诱导多种细胞的细胞凋亡，包括早幼粒细胞性白血病细胞，Jurkat细胞，心肌细胞和结肠腺癌细胞。启动细胞内信号和即早基因诱导。选择性信号激动剂。强效Jun-NH2末端激酶（JNK）激动剂。活化促分裂原活化蛋白（MAP）激酶（JNK/ SAPK和p38/RK）。抗原虫剂。|
|个人防护设备||Eyeshields,Faceshields,Gloves,type P2 (EN 143) respirator cartridges|
Malaria is a devastating infection caused by protozoa of the genus Plasmodium. Drug resistance is widespread, no new chemical class of antimalarials has been introduced into clinical practice since 19...Read More
In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen.
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Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans
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MKK6 activates myocardial cell NF-kappaB and inhibits apoptosis in a p38 mitogen-activated protein kinase-dependent manner.
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Regulation of neuronal excitability by interaction of fragile X mental retardation protein with slack potassium channels.
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Anisomycin induces apoptosis of glucocorticoid resistant acute lymphoblastic leukemia CEM-C1 cells via activation of mitogen-activated protein kinases p38 and JNK.
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DNA damage induces nucleoid compaction via the Mre11-Rad50 complex in the archaeon Haloferax volcanii.
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Functional integrity of the retrosplenial cortex is essential for rapid consolidation and recall of fear memory.
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Solid-phase synthesis and anti-infective activity of a combinatorial library based on the natural product anisomycin
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