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茴香霉素

产品编号 A102397 | CAS号 22862-76-6 | Aladdin
Anisomycin from Streptomyces griseolus
97%
组合的产品项目
货号 规格 库存 价格 数量
A102397-100mg 97% 上海(2)
北方(3)
 
A102397-25mg 97% 上海(预计4-8周)
北方(预计4-8周)
 
A102397-5mg 97% 上海(1)
北方(5)
 
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属性

敏感性 对热敏感,易吸潮
密度 1.2100
存贮条件 储存温度2-8℃

描述

产品介绍 Soluble in methanol (20 mg/ml clear, faint yellow solution), ethanol (25 mg/ml), DMSO (50 mg/ml), alcohols, esters, ketones, chloroform, benzene (slightly), toluene (slightly), hexane (slightly), water (2 mg/ml), and ethyl acetate (10 mg/ml clear, colorless solution), DMF (20 mg/ml), and PBS pH 7.2 (0.5 mg/ml).
别名 (2R,3S,4S)-2-(4-甲氧苯基)-3,4-吡咯二醇 3-乙酸酯;(2R,3S,4S)-2-(4-Methoxybenzyl)-3,4-pyrrolidinediol-3-acetate; 2-[(4-Methoxyphenyl)methyl]-3,4-pyrrolidinediol 3-acetate; Flagecidin
生化机理 从Streptomyces griseolus 分离的抗生素,抑制蛋白质合成。通过抑制真核生物核糖体肽基转移酶的活性而发挥作用。据报道,诱导多种细胞的细胞凋亡,包括早幼粒细胞性白血病细胞,Jurkat细胞,心肌细胞和结肠腺癌细胞。启动细胞内信号和即早基因诱导。选择性信号激动剂。强效Jun-NH2末端激酶(JNK)激动剂。活化促分裂原活化蛋白(MAP)激酶(JNK/ SAPK和p38/RK)。抗原虫剂。
应用 蛋白质合成抑制剂。引起PC12细胞的凋亡
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标识符号 GHS06 GHS06
信号词 Danger
风险声明 (欧洲) 25
安全声明(欧洲) 45
警示性声明 P301+P310
危害码(欧洲) T
危害声明 H301
个人防护设备 Eyeshields,Faceshields,Gloves,type P2 (EN 143) respirator cartridges
RTECS BZ9800000
WGK德国 3
UN代码 3462
参考文献
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