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1-氨基环丁烷羧酸

¥ 349.00

产品编号 A102435 | CAS号 22264-50-2 | Aladdin
1-Amino-1-cyclobutanecarboxylic acid
97%
组合的产品项目
货号 规格 库存 价格 数量
A102435-1g 97% 上海(预计3-7周)
北方(预计3-7周)
 
A102435-25g 97% 上海(预计3-7周)
北方(预计3-7周)
 
A102435-5g 97% 上海(预计3-7周)
北方(预计3-7周)
 
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属性

密度 1.2900
熔点 261°C
溶解性 Soluble to 100 mM in Water

描述

产品介绍 1-Amino-1-cyclobutanecarboxylic acid is an NMDA receptor antagonist acting at the glycine site.
别名 1-氨基-1-环丁烷羧酸;1-Aminocyclobutanecarboxylic acid
应用 An NMDA receptor antagonist that acts at the glycine site
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标识符号 GHS07 GHS07
信号词 Warning
风险声明 (欧洲) 22,36/37/38
安全声明(欧洲) 26,36
警示性声明 P261,P305+P351+P338
危害码(欧洲) Xn
危害声明 H302,H315,H319,H335
个人防护设备 dust mask type N95 (US),Eyeshields,Faceshields,Gloves
RTECS GU1336000
WGK德国 3
参考文献
E A Bulantseva, E M Glinka, M A Protsenko, E G Sal'kova
We studied changes in the intensity of ethylene release and accumulation of 1-aminocyclopropane-1-carboxylic acid during ripening of two apple varieties characterized by various physiological states a...Read More
M M Gatos, F F Formaggio, M M Crisma, C C Toniolo, G M GM Bonora, Z Z Benedetti, B B Di Blasio, R R Iacovino, A A Santini, M M Saviano, J J Kamphuis
A series of N- and C-protected, monodispersed homo-oligopeptides (to the dodecamer level) from the small-ring alicyclic C alpha, alpha-dialkylated glycine 1-aminocyclobutane-1-carboxylic acid (Ac4c) a...Read More
Y Y Kosugi, N N Oyamada, S S Satoh, T T Yoshioka, E E Onodera, Y Y Yamada
We partially purified 1-aminocyclopropane-1-carboxylate (ACC) oxidase from senescing petals of carnation (Dianthus caryophyllus L. cv. Nora) flowers and investigated its general characteristics, and, ...Read More
E E Gershonov, R R Granoth, E E Tzehoval, Y Y Gaoni, M M Fridkin
Four novel 2,4-methano amino acids (MAAs, 1-aminocyclobutane-1-carboxylic acids) were synthesized. These include the basic MAA analogs of lysine (16), ornithine (5), and arginine (6) and the neutral m...Read More
J K JK Relton, P J PJ Strijbos, A L AL Cooper, N J NJ Rothwell
Arachidonic acid [20:4(N-6)] has been implicated in neurological damage induced by cerebral ischaemia. Membrane arachidonate concentrations can be reduced by changes in dietary fat intake. Therefore, ...Read More
V N VN Balaji, K K Ramnarayan, M F MF Chan, S N SN Rao
Conformationally constrained peptidomimetics are being increasingly used in the development of 3-D pharmacophores of peptide-based drug candidates and to alter their metabolic stability towards achiev...Read More
K F KF Hübner, S S Krauss, L C LC Washburn, W D WD Gibbs, E C EC Holloway
Eight patients with proven or suspected neoplastic lesions were examined with 1-aminocyclobutane C-11-carboxylic acid and 1-aminocyclopentane C-11-carboxylic acid using positron emission computed tomo...Read More
T S TS Rao, J A JA Cler, R P RP Compton, M R MR Emmett, S S Mick, E T ET Sun, S S Iyengar, P L PL Wood
Following intravenous administration, 1-aminocyclobutane-1-carboxylate (ACBC, 100 mg/kg), a N-methyl-D-aspartate (NMDA)-associated glycine receptor antagonist, was eliminated with a T1/2 of 5 min in m...Read More
R P RP Compton, W F WF Hood, J B JB Monahan
Activation of the N-methyl-D-aspartate (NMDA) receptor complex is subject to modulation via interactions at a coupled [3H]glycine recognition site in rat brain synaptic plasma membranes (SPM). We exam...Read More
R H Porter, R S Briggs, P J Roberts
The competitive N-methyl-D-aspartate (NMDA) receptor antagonist [3H]3-((+-)-2-carboxypiperazin-4-yl)propyl-1-phosphonic acid ([3H]CPP) interacts with two discrete binding sites, one of high- and the o...Read More
L C LC Washburn, T T TT Sun, B B Byrd, R L RL Hayes, T A TA Butler
1-Aminocyclobutane[14C]carboxylic acid [C-14) ACBC] was incorporated preferentially by several tumor types in rats and hamsters. The agent was cleared rapidly from rat blood, attaining its maximum tis...Read More
Cassandra L Kussius, Gabriela K Popescu
Activation of ligand-gated channels is initiated by the binding of small molecules at extracellular sites and culminates with the opening of a membrane-embedded pore. To investigate how perturbations ...Read More
Atsushi Inanobe, Hiroyasu Furukawa, Eric Gouaux
Partial agonists produce submaximal activation of ligand-gated ion channels. To address the question of partial agonist action at the NR1 subunit of the NMDA receptor, we performed crystallographic an...Read More
M C MC Pirrung, J J Cao, J J Chen
The chemical mechanism of the final step of ethylene biosynthesis (the conversion of 1-aminocyclopropanecarboxylic acid, ACC, to ethylene by ACC oxidase, the ethylene-forming enzyme, EFE) is poorly un...Read More
G B GB Watson, M A MA Bolanowski, M P MP Baganoff, C L CL Deppeler, T H TH Lanthorn
ACBC has been reported to have the binding profile of an antagonist at the glycine site of the NMDA receptor. In Xenopus oocytes injected with rat brain mRNA, we have confirmed the antagonist action o...Read More
W F WF Hood, E T ET Sun, R P RP Compton, J B JB Monahan
We're sorry this abstract is currently not available....Read More
I I Varela, M M Avila, J M JM Mato, L L Hue
The ability of the insulin-induced phospho-oligosaccharide to stimulate amino acid transport was studied in isolated rat hepatocytes. At low alpha-aminoisobutyric acid concentrations (0.1 mM), both 10...Read More
G B GB Watson, T H TH Lanthorn
In Xenopus oocytes, injected with mRNA from the brain of the rat, the characteristics of the cyclic homologues of glycine, ACPC, ACBC and cycloleucine have been examined. 1-Aminocyclopropane-1-carboxy...Read More

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