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2-氨基芴

¥ 124.74

产品编号 A103032 | CAS号 153-78-6 | Aladdin
2-Aminofluorene
98%
组合的产品项目
货号 规格 库存 价格 数量
A103032-1g 98% 上海(>10)
北方(>10)
 
A103032-25g 98% 上海(>10)
北方(预计3-5个工作日)
 
A103032-5g 98% 上海(>10)
北方(预计3-5个工作日)
 
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属性

密度 1.2030
熔点 127°C

描述

产品介绍 能溶于醇和醚,不溶于水。
别名 2-氨基芴 ;芴-2-胺;2-Fluorenamine 2-Fluorenylamine
应用 用于有机合成。2-Fluorenamine
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风险声明 (欧洲) R40;
安全声明(欧洲) S36/37;S45;
个人防护设备 Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter
RTECS LL5075000
WGK德国 3
UN代码 2811
参考文献
A S Zhuk, E I Stepchenkova, A V Dukel'skaia, E V Daev, S G Inge-Vechtomov
The hypothesis on a relationship between the high frequency of mitotic disturbances in bone marrow cells and the change in the activity of the S9 liver fraction containing promutagen-activating enzyme...Read More
V G Vaidyanathan, Lifang Xu, Bongsup P Cho
We used surface plasmon resonance (SPR) to characterize the binding interactions between the exonulease-free Klenow fragment (Kf-exo(-)) and unmodified and modified dG adducts derived from arylamine c...Read More
Vipin Jain, Benjamin Hilton, Satyakam Patnaik, Yue Zou, M Paul Chiarelli, Bongsup P Cho
Nucleotide excision repair (NER) is a major repair pathway that recognizes and corrects various lesions in cellular DNA. We hypothesize that damage recognition is an initial step in NER that senses co...Read More
Rampal
In the current study, isolation of glucosinolate degradation products was done in 4 different incubation solutions with different pHs based on the fact that distinct hydrolytic products are formed at ...Read More
Natalie L Milic, Suong N T Ngo, Ceilidh L Marchant, Tamara A Height, Ross A McKinnon
Cytochromes P450 (CYPs) are critically important in the oxidative metabolism of a diverse array of xenobiotics and endogenous substrates. We have previously reported the cloning and characterisation o...Read More
Ali Bilici, Ismet Kaya, Mehmet Y?ld?r?m
We're sorry this abstract is currently not available....Read More
Susan Lentz, Rob Eversole, J McHugh Law, Jay C Means
Chronic exposure to arylamines through diet and/or smoking has been associated with genetic changes and tumorigenesis. Cellular proliferation, apoptosis, and histological changes in liver tissue were ...Read More
Olga O Rechkoblit, Alexander A Kolbanovskiy, Lucy L Malinina, Nicholas E NE Geacintov, Suse S Broyde, Dinshaw J DJ Patel
The aromatic amine carcinogen 2-aminofluorene (AF) forms covalent adducts with DNA, predominantly with guanine at the C8 position. Such lesions are bypassed by Y-family polymerases such as Dpo4 via er...Read More
Keiko K Inami, Mikiko M Okazawa, Masataka M Mochizuki
Chemical models for cytochrome P450, consisting of water-insoluble or water-soluble iron porphyrin plus an oxidant, have been used to detect the mutagenicity of promutagens in genotoxicity assays. The...Read More
Sampath S Kaleeswaran, Padmanabhan P Sriram, Daivasigamani D Prabhu, , , Lalgudi Narayanan LN Mathuram
Silymarin, a polyphenolic flavonoid isolated from milk thistle (Silybum marianum), is being used clinically in Europe and Asia for the treatment of liver diseases. Silymarin has a strong antioxidative...Read More
Mei-Due MD Yang, Shuw-Yuan SY Lin, Tsan-Hung TH Chiu, Chin-Chung CC Lin, Meng-Liang ML Lin, Shu-Chun SC Hsu, Chao-Lin CL Kuo, Ming-Jyh MJ Sheu, Chih-Chung CC Wu, Song-Shei SS Lin, Jing-Gung JG Chung
The effects of oral luteolin on the N-acetylation and metabolism of 2-aminofluorene (AF) in vivo were investigated in bladder, blood, colon, kidney, liver, feces, urine, cerebrum, cerebellum and pinea...Read More
Felicia A Jefferson, Gong H Xiao, David W Hein
Aromatic and heterocyclic amine carcinogens present in the diet and in cigarette smoke induce breast tumors in rats. N-acetyltransferase 1 (NAT1) and N-acetyltransferase 2 (NAT2) enzymes have importan...Read More
Stephen W SW Holman, Patricia P Wright, G John GJ Langley
A 50 m/z unit loss from protonated 4-benzenesulfinyl-3-methylphenylamine has been observed and investigated using electrospray ionisation quadrupole ion trap mass spectrometry (ESI-QIT-MS). It was hyp...Read More
Nidhi Jain, Yana K Reshetnyak, Lan Gao, M Paul Chiarelli, Bongsup P Cho
Fluorescence spectroscopy was used to study carcinogen-induced conformational heterogeneity in DNA duplexes. The fluorophore 2-aminopurine (AP) was incorporated adjacent (5') to the lesion (G*) i...Read More
Mark E ME Lee, Paul P Urso
Here, we attempt to reveal how 2-aminofluorene (AF), benzo(alpha)pyrene (BP) and their major metabolites affect T-cell responses to antigenic and mitogenic stimuli. P-450-related metabolism of these p...Read More
H H Zeytinoglu, Z Z Incesu, B Ayaz BA Tuylu, A O AO Turk, B B Barutca
Naturally occurring compounds can have protective effects towards mutagens and carcinogens as shown by numerous studies. In the present study, the genotoxic/antigenotoxic activities of the extract fro...Read More
E E Miadokova, S S Nadova, V V Vlckova, V V Duhova, M M Kopaskova, L L Cipak, P P Rauko, P P Mucaji, D D Grancai
The extract of artichoke Cynara cardunculus L. (CCE) was investigated for its potential antigenotoxic and antioxidant effects using four experimental model systems. In the Saccharomyces cerevisiae mut...Read More
Jau-Hong JH Lee, Hsu-Feng HF Lu, Der-Yean DY Wang, Dar-Ren DR Chen, Chin-Cheng CC Su, Yi-Shuan YS Chen, Jen-Hung JH Yang, Jing-Gung JG Chung
Tamoxifen was used to determine the effects of N-acetyltransferase(NAT) activity and 2-aminofluorene (2-AF)-DNA adduct formation in human breast cancer cells. Breast cancer cells were categorized into...Read More
Jennifer A Sanders, Kate E Brilliant, Danielle Clift, Ajay Patel, Bruno Cerretti, Patricia Claro, David R Mills, Douglas C Hixson, Philip A Gruppuso
Oval cell activation occurs under conditions of severe liver injury when normal hepatocyte proliferation is blocked. Recent studies have shown that a subset of hepatocellular carcinomas expresses oval...Read More
Prabhjit Kaur, Madhu Chandel, Subodh Kumar, Neeraj Kumar, Bikram Singh, Satwinderjeet Kaur
Rubia cordifolia L. (Rubiaceae) is an important medicinal plant used in the Ayurvedic medicinal system. Its use as a traditional therapeutic has been related to the treatment of skin disorders and can...Read More
Linlin Zhao, John B Schenkman, James F Rusling
We demonstrate for the first time the combination of human liver cytosol and microsomal enzyme sources into an electro-optical array to screen for reactive metabolites produced in multi-enzyme metabol...Read More
Venkataramana Vooradi, Louis J Romano
The well-studied aromatic amine carcinogen, N-2-acetylaminofluorene (AAF), forms adducts at the C8 position of guanine in DNA. Unlike replicative polymerases, Y-family polymerases have been shown to h...Read More
Dominique Y Burnouf, Jér?me E Wagner
The model carcinogen N-2-acetylaminofluorene covalently binds to the C8 position of guanine to form two adducts, the N-(2'-deoxyguanosine-8-yl)-aminofluorene (G-AF) and the N-2-(2'-deoxyguan...Read More
Piyatilake Adris, Carlos Lopez-Estra?o, King-Thom Chung
Pseudomonas aeruginosa is an important opportunistic pathogen of the human urinary bladder. Similar to rat liver S9, the cell-free extract from P. aeruginosa caused significant increase of histidine r...Read More
S S Torres-Cartas, Y Y Martín-Biosca, R M RM Villanueva-Cama?as, S S Sagrado, M J MJ Medina-Hernández
Mutagenicity is a toxicity endpoint associated with the chronic exposure to chemicals. Aromatic amines have considerable industrial and environmental importance due to their widespread use in industry...Read More