|别名||氯丙烯 ;烯丙基氯,α-氯丙烯,3-氯-1-丙烯,3-氯丙烯;3-chloropropene 3-Chloro-1-propene|
|标识符号||GHS02, GHS07, GHS08, GHS09|
|个人防护设备||Eyeshields,Faceshields,full-face respirator (US),Gloves,multi-purpose combination respirator cartridge (US)|
Syntheses of trisila analogues of allyl chlorides and their transformations to chlorocyclotrisilanes, cyclotrisilanides, and a trisilaindane.
The rearrangements of (chlorosilyl)disilenes R2(Cl)Si-(Tip)Si=SiTip2 (5a,b: Tip = 2,4,6-iPr3C6H2, a: R = Me, b: R = Ph) quantitatively yield the isomeric chlorocyclotrisilanes (6a,b). The disilene pre...Read More
Regio- and enantioselective o-allylation of phenol and alcohol catalyzed by a planar-chiral cyclopentadienyl ruthenium complex.
[In vivo and in vitro determination of changes of electrophysiology in rats with allyl chloride poisoning].
To compare the results of in vivo and in vitro in determination of the changes of allyl chloride (AC)-induced electrophysiology in rats sciatic nerve....Read More
Expression changes of apoptotic-related proteins in nerve tissues of rats treated with allyl chloride
Allyl chloride (AC) is widely used in industries as raw material and has been reported to produce occupational peripheral neuropathies in man chronically exposure to it. Although many studies have bee...Read More
Chronic exposure to allyl chloride (AC) is known to produce a central-peripheral distal axonopathy. To access the biomarker of exposure and elucidate the mechanism of neuropathy induced by AC, we perf...Read More
Cycloadditions on diamond (100) 2 x 1: observation of lowered electron affinity due to hydrocarbon adsorption.
The adsorption of allyl alcohol, acrylic acid, and allyl chloride, as well as unsaturated organic molecules such as acetylene and 1,3 butadiene, on reconstructed diamond (100) 2 x 1 have been investig...Read More
To accurately know the time-dependent changes of the lipid peroxidation and antioxidative status for elucidating the mechanism of neuropathy induced by allyl chloride (AC), the malondialdehyde (MDA), ...Read More
To dissect the molecular mechanism of toxic neuropathy induced by allyl chloride (AC)....Read More
In this study, 124 mg/kg of allyl chloride (one-fifth of LD50) was administered to mice by a single subcutaneous injection and its effects on the male reproductive system were evaluated at 4 days, 9 d...Read More
Copper- and phosphine-ligand-free palladium-catalyzed direct allylation of electron-deficient polyfluoroarenes with allylic chlorides.
Simply id(all)ylic: a copper- and phosphine-ligand-free Pd-catalyzed direct allylation of electron-deficient polyfluoroarenes with allylic chlorides and the reaction mechanism are described. The simpl...Read More
Fluoride-mediated elimination of allyl sulfones: application to the synthesis of a 2,4-dimethyl-A-ring vitamin D3 analogue.
A coupling strategy for the synthesis of 2,4-dimethyl-1α,25(OH)(2)D(3) is achieved which involves methylation of a pro-A ring vinyl sulfone and in situ traping of the allyl sulfonyl anion with a CD r...Read More
Diastereocontrol in asymmetric allyl-allyl cross-coupling: stereocontrolled reaction of prochiral allylboronates with prochiral allyl chlorides.
Palladium-catalyzed allyl-allyl cross-coupling was investigated with substituted prochiral allylic boronates. These reactions deliver products bearing adjacent stereocenters, and the issue of diastere...Read More
A serendipitous synthesis of (+)-gregatin B, second structure revisions of the aspertetronins, gregatins, and graminin A, structure revision of the penicilliols.
A (DHQN)(2)AQN-promoted asymmetric dihydroxylation (92% ee) of the allyl chloride derived from enynol (E)-13 and an 8-step sequence provided access to the hydroxyethylated furanone (R)-21. Oxidation w...Read More
Multiple, complementary methods are reported for the chemical conversion of cysteine to S-allyl cysteine on protein surfaces, a useful transformation for the exploration of olefin metathesis on protei...Read More
The article covers results of examination of workers engaged into chemical production and contacting neurotoxic factors varying in nature. Findings are disorders of cholesterol metabolism in individua...Read More
Carbocycle synthesis through facile and efficient palladium-catalyzed allylative de-aromatization of naphthalene and phenanthrene allyl chlorides.
Product selectivity control based on a liquid-liquid parallel laminar flow has been successfully demonstrated by using a microreactor. Our electrochemical microreactor system enables regioselective cr...Read More
Acrylamide (ACR) is a conjugated type-2 alkene that produces synaptic toxicity presumably by sulfhydryl adduction. The alpha,beta-unsaturated carbonyl of ACR is a soft electrophile and, therefore, add...Read More
The Ni-catalyzed coupling of allyl chlorides and enynes has been developed; the cyclization of enynes was triggered by the addition of pi-allylnickel species to the alkyne part, followed by the incorp...Read More
To evaluate the use of urinary mercapturic acids as a biomarker of human exposure to allyl chloride (3-chloropropene) (AC). During three regular shut down periods in a production factory for AC, both ...Read More
Biotransformation of allyl chloride in the rat. Influence of inducers on the urinary metabolic profile.
Allyl chloride (AC) is used as intermediate in the synthesis of epichlorohydrin (ECH). We investigated the biotransformation of AC in rats to select potential urinary biomarkers of exposure. For this ...Read More
Chronic exposure to allyl chloride (ALL) is known to produce a central-peripheral distal axonopathy. In relation to the mechanism(s), the present study was conducted to examine the abilities of ALL an...Read More
Halogenated derivatives QSAR model using spectral moments to predict haloacetic acids (HAA) mutagenicity