|别名||氯化丙烯酸;烯丙酰氯;Propenoyl chloride;2-Propenoyl chloride|
|标识符号||GHS02, GHS05, GHS06|
Hydroxamic acid-containing hydrogels for nonabsorbed iron chelation therapy: synthesis, characterization, and biological evaluation.
Iron overload is a severe clinical condition and can be largely prevented by the use of iron-specific chelating agents. A successful iron chelator needs to be orally active, nontoxic, and selective. I...Read More
A series of amphiphilic random block co-polymers were synthesized by the condensation of hydrophobic polycaprolactone diol (PCL diol) with hydrophilic dicarboxy poly(ethylene glycol) (PEG-diacid), obt...Read More
Acryloyl Chloride and Acryloyl Isocyanate (CH 2 CHC(O)X, X = Cl, NCO): A HeI Photoelectron Spectroscopy and Theoretical Study
Acryloyl isocyanate CH(2)=CHC(O)NCO is quantitatively prepared by the metathesis reaction between CH(2)=CHC(O)Cl and AgNCO. Also, jointly with acryloyl chloride, their molecular and electronic structu...Read More
Combined CASSCF and MR-CI study on photoinduced dissociation and isomerization of acryloyl chloride.
The potential energy surfaces of isomerization and dissociation reactions for CH2CHCOCl in the S0, T1, T2, and S1 states have been mapped with DFT, CASSCF, MP2, and MR-CI calculations. Rate constants ...Read More
Polymeric nanoparticles of AADG cross-linked with MBA encapsulating water soluble macromolecules such as FITC-Dextran have been prepared in the reverse micellar system. The particles obtained were of ...Read More
Radiosynthesis of ML03, a novel positron emission tomography biomarker for targeting epidermal growth factor receptor via the labeling synthon: [11C]acryloyl chloride.
An automated procedure for the radiosynthesis of the labeling synthon [11C]acryloyl chloride was developed and applied for labeling several N-acryl amides with carbon-11. [11C]-6-acrylamido-4-(3,4-dic...Read More
Poly(4-vinyl-N-alkylpyridinium bromide) was covalently attached to glass slides to create a surface that kills airborne bacteria on contact. The antibacterial properties were assessed by spraying aque...Read More
Three university students were exposed to toxic vapours (acryloyl chloride 96% and methacrylic anhydride 94%) in a laboratory accident. They all gave a history of minimal exposure and presented with m...Read More
[Effect of progressive chemical modification on the activity and thermal stability of soluble and immobilized glucoamylase].
The chemical modification of glucoamylase from Aspergillus niger with acryloylchloride has been studied. It was shown that the first 60--70% of the total amount of available amino groups of the enzyme...Read More
[The heterogeneous character of protein modification during substitution of their amino groups. Acylation of alpha-chymotrypsin].
Thin-layer isoelectric focusing of chymotrypsin modified by stepwise acylation with acryloyl chloride or maleic anhydride revealed a high heterogeneity of modification products, with a maximal number ...Read More
Affinity and stability modifications of immobilized alcohol dehydrogenase through multipoint copolymerization.
Yeast alcohol dehydrogenase (alcohol:NAD+ oxidoreductase, EC 184.108.40.206), a potentially useful enzyme for cofactor regeneration processes, was covalently immobilized in a multipoint fashion by activation...Read More
Enzymatic peptide synthesis in organic solvent mediated by gels of copolymerized acrylic derivatives of alpha-chymotrypsin and polyoxyethylene.
Copolymers of acrylated derivatives of alpha-chymotrypsin and polyethylene glycol (PEG) have been prepared and used as biocatalysts for the synthesis of model peptides in organic solvent containing a ...Read More
DNA nanogels composed of chitosan and Pluronic with thermo-sensitive and photo-crosslinking properties.
Chitosan/Pluronic hydrogels were prepared to develop injectable depot systems for gene therapy to enhance local transgene expression at injection sites. Water-soluble chitosan and Pluronic were separa...Read More
The purpose of this work is to prepare a pH-sensitive hydrogel membrane of sodium carboxymethyl cellulose acrylate for drug delivery and other biomedical applications. The hydrogel was made by esterif...Read More
Crystal Structure of Saccharopine Reductase from Magnaporthe grisea, an Enzyme of the @a-Aminoadipate Pathway of Lysine Biosynthesis
Background: The biosynthesis of the essential amino acid lysine in higher fungi and cyanobacteria occurs via the @a-aminoadipate pathway, which is completely different from the lysine biosynthetic pat...Read More
Platelet adhesion and complement activation studies on poly(N-alkyl mono and disubstituted) acrylamide derivatives.
Poly(N-alkyl mono and disubstituted) acrylamide derivatives were synthesized from poly(acryloyl chloride) by monomer analogous reaction. The polymers were characterized by FTIR-ATR and GPC. The contac...Read More
The reproducible preparation of [1-11C]propenoic acid (acrylic acid) in 45-50% radiochemical yield was made possible by careful control of the temperature and time of the 11C carbonation of ethenylmag...Read More
Glycosaminoglycans and its derivatives have gained increasing attention for the fabrication of hydrogels usable in biomedicine. Starting from high molecular weight hyaluronan, a natural glycosaminogly...Read More