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对氨基水杨酸

产品编号 A105007 | CAS号 65-49-6 | Aladdin
4-Aminosalicylic acid
98%
组合的产品项目
货号 规格 库存 价格 数量
A105007-100g 98% 上海(预计4-8周)
北方(2)
 
A105007-2.5kg 98% 上海(1)
北方(预计3-5个工作日)
 
A105007-500g 98% 上海(4)
北方(4)
 
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属性

敏感性 对光和空气敏感
密度 1.5450
熔点 150-151°C
溶解性 Soluble in water (2 g/l) at 20 °C, dilute sodium hydroxide, dilute nitric acid, ether (slightly), methanol, acetone, and ethanol (1 G SOL IN 21 ML ALC). Virtually insoluble in benzene, chloroform, and carbon tetrachloride
存贮条件 充氩保存

描述

产品介绍 4-Aminosalicylic acid is an inhibitor of NF κ B.
别名 4-氨基水杨酸; 4-氨基柳酸; 4-氨基-2-羟基苯甲酸; 4-氨基-2-羟基苯甲酸;4-Amino-2-hydroxybenzoic acid; PAS
应用 A antibacterial capable of inhibiting the growth of Mycobacterium tuberculosis
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标识符号 GHS07 GHS07
信号词 Warning
风险声明 (欧洲) R22;R36
安全声明(欧洲) S26
警示性声明 P305+P351+P338
危害码(欧洲) Xn
危害声明 H319
个人防护设备 dust mask type N95 (US),Eyeshields,Gloves
RTECS VO1225000
WGK德国 2
Merck Index 477
参考文献
Diana Couto, Daniela Ribeiro, Marisa Freitas, Ana Gomes, José L F C Lima, Eduarda Fernandes
Sulfasalazine is a prodrug composed by a molecule of 5-aminosalicylic acid (5-ASA) and sulfapyridine (SP), linked by an azo bond, which has been shown to be effective in the therapy of inflammatory bo...Read More
Dinamene Santos, M Camila Batoreu, Michael Aschner, Ana P Marreilha dos Santos
Manganese (Mn) is an essential metal for biological systems; however, occupational or clinical exposure to high levels of Mn can produce a neurological disorder called manganism. Oxidative stress and ...Read More
S S Thee, E W EW Z?llner, M M Willemse, A C AC Hesseling, K K Magdorf, H S HS Schaaf
Ethionamide (ETH) treatment may cause hypothyroidism. Clinical data, serum thyroid stimulating hormone (TSH) and free thyroxine (fT4) levels were retrospectively assessed in 137 children receiving ant...Read More
Chih-Cheng CC Lai, Che-Kim CK Tan, Yu-Tsung YT Huang, Chun-Hsing CH Liao, Po-Ren PR Hsueh
We're sorry this abstract is currently not available....Read More
Joo-Hee Kim, Seung Hun Jang, Dong Hoon Kim, Sunghoon Park, Dong-Gyu Kim, Ki-Suck Jung
We're sorry this abstract is currently not available....Read More
A C Liwa, H S Schaaf, B Rosenkranz, H I Seifart, A H Diacon, P R Donald
There are no paediatric data regarding slow-release para-aminosalicylic acid (PAS). We studied PAS plasma concentrations in 10 children receiving a single 150 mg/kg dose daily or 75 mg/kg twice daily ...Read More
Sumit Chakraborty, Todd Gruber, Clifton E Barry, Helena I Boshoff, Kyu Y Rhee
Folate biosynthesis is an established anti-infective target, and the antifolate para-aminosalicylic acid (PAS) was one of the first anti-infectives introduced into clinical practice on the basis of ta...Read More
V E VE Sagynbaeva, L B LB Lazebnik, O V OV Kniazev, A I AI Parfenov, L I LI Efremov
Detection of IgM and IgG Chlamydia and Mycoplasma pneumoniae indicates an aggravation of intracellular infections, including, possibly, due to immunosuppressive therapy. It is possible that the intrac...Read More
Gaurav Vadnerkar, Suneela Dhaneshwar
Sterically hindered esters or esters of drugs with macromolecular carriers like dextran and cyclodextrin find wide applicability in colon-targeted delivery. We report here synthesis, in vitro release ...Read More
Shuichi Yano, Kanako Kobayashi, Toshikazu Ikeda
Isoniazid (H) or rifampicin (R) mono-resistant disease can be treated easily and effectively with first-line drugs, while combined H and R resistance (ie, multidrug-resistant tuberculosis (MDRTB)) req...Read More
We're sorry this abstract is currently not available....Read More
Wei-Ping WP Qin, Tian-Jia TJ Liang, Yue-Ming YM Jiang
We're sorry this abstract is currently not available....Read More
A P Marreilha Dos AP Santos, Rui L RL Lucas, Vanda V Andrade, M Luísa ML Mateus, Dejan D Milatovic, Michael M Aschner, M Camila MC Batoreu
Chronic, excessive exposure to manganese (Mn) may induce neurotoxicity and cause an irreversible brain disease, referred to as manganism. Efficacious therapies for the treatment of Mn are lacking, man...Read More
Fuqiang F An, Ruikui R Du, Xiaohua X Wang, Min M Wan, Xin X Dai, Jianfeng J Gao
In this study, 5-aminosalicylic acid (5-ASA) was successfully grafted onto the poly(glycidyl methacrylate) (PGMA) macromolecular chains of PGMA/SiO(2) to obtain adsorbent ASA-PGMA/SiO(2). The adsorpti...Read More
Bente Mertz BM N?rg?rd
The clinical epidemiological studies included in this thesis fall into three parts. The first part includes studies on birth outcome in women with ulcerative colitis. The second part includes pharmaco...Read More
Amanda S Fivian-Hughes, Joanna Houghton, Elaine O Davis
Thymidylate synthase (TS) enzymes catalyse the biosynthesis of deoxythymidine monophosphate (dTMP or thymidylate), and so are important for DNA replication and repair. Two different types of TS protei...Read More
Cezary C Chojnacki, Ewa E Walecka-Kapica, Grazyna G Klupinska, Monika M Paw?owicz, Antoni A Florkowski, Patrycja P Wachowska-Kelly, Jan J Chojnacki
In order to maintain ulcerative colitis (UC) in remission, chronic use of aminosalicylates is recommended. All patients have a fear of the recurrence of symptoms, which makes their mental state and qu...Read More
S M SM Vesenbeckh, J J Becker, C C Huhnt, B B Karras, T T TT Bauer, H H Mauch, H H Rüssmann, N N Sch?nfeld
para-Aminosalicylic acid (PAS) is commonly used in the treatment of drug-resistant tuberculosis, including multidrug-resistant tuberculosis. Since its first use in the 1940s, hypersensitivity reaction...Read More
Lan Hong, Wendy Jiang, Hao Pan, Yueming Jiang, Su Zeng, Wei Zheng
para-aminosalicylic acid (PAS; 4-amino-2-hydroxybenzoic acid), an antituberculosis drug in use since the 1950s, has recently been suggested to be an effective agent for treatment of manganese-induced ...Read More
Jie J Zhang, Yuanyuan Y Shan, Xiaoyan X Pan, Chen C Wang, Wenfang W Xu, Langchong L He
Neuraminidase (NA) is a major glycoprotein of influenza virus which is essential for viral infection. It offers a potential target for antiviral drug design and discovery. To develop novel potent neur...Read More
Tze Liang Goh, Cindy R Towns, Katharine L Jones, Joshua T Freeman, Colin S Wong
In 2010, an immigrant from Burma was the first person to be diagnosed in New Zealand with extensively drug-resistant tuberculosis (XDR-TB). The strain of Mycobacterium tuberculosis is the most resista...Read More
Kim S Sugamori, Debbie Brenneman, Denis M Grant
Human arylamine N-acetyltransferase 2 (NAT2) mediates the biotransformation of arylamine drugs and procarcinogens into either innocuous or reactive DNA-damaging metabolites and is expressed predominan...Read More
Lan Hong, Wendy Jiang, Wei Zheng, Su Zeng
Para-aminosalicylic acid (PAS), an approved drug for treatment of tuberculosis, is a promising therapeutic agent for treatment of manganese (Mn)-induced parkinsonian syndromes. Lack of a quantifying m...Read More
Peng
This study uses 4,4'-dinitrostilbene-2,2'-disulfonic acid (DNS) wastewater to produce paramycin (4-amino-2-hydroxybenzoic acid), an antitubercular agent and important pharmaceutical intermed...Read More
Wei Zheng, Yue-Ming Jiang, Yanshu Zhang, Wendy Jiang, Xueqian Wang, Dallas M Cowan
Para-aminosalicylic acid (PAS), an FDA-approved anti-tuberculosis drug, has been used successfully in the treatment of severe manganese (Mn)-induced Parkinsonism in humans [Jiang Y-M, Mo X-A, Du FQ, F...Read More