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N-乙酰-D-氨基葡萄糖

产品编号 A105211 | CAS号 7512-17-6 | Aladdin
N-Acetyl-D-glucosamine
98%
组合的产品项目
货号 规格 库存 价格 数量
A105211-100g 98% 上海(10)
北方(预计3-5个工作日)
 
A105211-25g 98% 上海(>10)
北方(预计3-5个工作日)
 
A105211-500g 98% 上海(7)
北方(预计3-5个工作日)
 
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属性

敏感性 易吸潮
旋光率 40.5 ° (C=1, H2O)
密度 1.5000
熔点 196.0–205.0°C
存贮条件 储存温度2-8°C

描述

产品介绍 溶于水。
别名 N-乙酰-D-氨基葡萄糖 ;N-乙酰氨基葡萄糖,2-(乙酰基氨基)-2-脱氧-D-葡萄糖,N-乙酰葡萄糖胺;2-Acetamido-2-deoxy-D-glucose 2-Acetamido-2-deoxy-D-glucopyranose N-Acetyl-D-glucosamine N-[2,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl]acetamide D-GlcNAc
应用 N-乙酰-D-氨基葡萄糖是生物细胞内许多重要多糖的基本组成单位,尤其是甲壳类动物的外骨骼含量最高。它是合成双歧因子的重要前体,在生物体内具有许多重要生理功能。
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安全声明(欧洲) S24/25
个人防护设备 Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter
WGK德国 3
参考文献
Peng Zhao, Stephanie H Stalnaker, Lance Wells
As a complex post-translational event, the biosynthesis, structures, and functions of O-linked glycans have attracted research interests in various aspects. The recent development of novel technologie...Read More
The thromboresistance of glucose-sensitive polymer hydrogels, modeling one of the functions of the pancreas, namely, the ability to secrete insulin in response to the introduction of glucose into the ...Read More
Petra ?edová, Radovan Buffa, Sofiane Kettou, Gloria Huerta-Angeles, Martina Hermannová, Veronika Leierová, Daniela ?mejkalová, Martina Moravcová, Vladimír Velebny
Native hyaluronan (HA) has been oxidized to polyaldehyde polymers with a degree of substitution (DS) of up to 50%. Two different procedures enabling the control of the degree of substitution were foll...Read More
Jon M Einarsson, Sven Bahrke, Bjarni Thor Sigurdsson, Chuen-How Ng, Petur Henry Petersen, Olafur E Sigurjonsson, Halldor Jonsson, Johannes Gislason, Finnbogi R Thormodsson, Martin G Peter
Recent evidences indicating that cellular kinase signaling cascades are triggered by oligomers of N-acetylglucosamine (ChOS) and that condrocytes of human osteoarthritic cartilage secrete the inflamma...Read More
K Zwierz, A Zalewska, A Zoch-Zwierz
Biological significance, structure and posttranslational processing of N-acetyl-beta-hexosaminidase isoenzymes are described. Clinical application of N-acetyl-beta-hexosaminidase is also reviewed....Read More
R A RA Muzzarelli
Human N-acetyl-beta-D-glucosaminidase, N-acetyl-alpha-D-glucosaminidase, endo-beta-N-acetylglucosaminidase, hexosaminidase, beta-N-acetylgalactosaminidase and glucocerebrosidase have not been so widel...Read More
Alexandra F Bruce, Kleoniki Gounaris
A thorough investigation was conducted for glycoside hydrolase activities in the secreted proteins of Trichinella spiralis. The data demonstrated that the only secreted glycosidase with significant ac...Read More
Alina A Kepka, S?awomir D SD Szajda, Anna A Jankowska, Napoleon N Waszkiewicz, Sylwia S Chojnowska, Krzysztof K Zwierz
Cells of the renal epithelium synthesize and excrete to urine many enzymes. Among more than 50 enzymes produced by epithelial cells of proximal tubules, only few have a diagnostic value. Determination...Read More
José de Jesús Pérez, Namrata D Udeshi, Jeffrey Shabanowitz, Sergio Ciordia, Silvia Juárez, Cheryl L Scott, Neil E Olszewski, Donald F Hunt, Juan Antonio García
O-GlcNAcylation is a dynamic protein modification which has been studied mainly in metazoans. We reported previously that an Arabidopsis thaliana O-GlcNAc transferase modifies at least two threonine r...Read More
Feng-Zhen Jin, Chao Yu, De-Zhang Zhao, Ming-Jun Wu, Zhu Yang
O-GlcNAcylation is a dynamic and reversible posttranslational modification of nuclear and cytoplasmic proteins. In recent years, the roles of O-GlcNAcylation in several human malignant tumors have bee...Read More
Lucy G Weaver, Yogendra Singh, Joanne T Blanchfield, Paul L Burn
Poly-N-acetylglucosamine (PNAG) saccharides are an important constituent of bacterial biofilms, such as those produced by Staphylococcus aureus. We have developed a simple two-step iterative method fo...Read More
Mitsutaka Ogawa, Yuki Sakakibara, Kazuo Kamemura
Previously, we demonstrated that the expression of myogenin, a critical transcription factor for myogenesis, is negatively regulated by O-linked β-N-acetylglucosamine (O-GlcNAc) glycosylation in mous...Read More
István Sebe, Barnabás Szabó, Romána Zelkó
Different types of polymers are widely used in biomedical, pharmaceutical and cosmetic purposes. Their applications are curbed, if the polymers can not break down by the body or if the polymer itself ...Read More
David D L Minh, Lee Makowski
A new way to use wide-angle x-ray solution scattering to study protein-ligand binding is presented. First, scattering patterns are measured at different protein and ligand concentrations. Multivariate...Read More
Kirsi Rilla, Sanna Oikari, Tiina A Jokela, Juha M T Hyttinen, Riikka K?rn?, Raija H Tammi, Markku I Tammi
Mammals have three homologous genes encoding proteins with hyaluronan synthase activity (Has1-3), all producing an identical polymer from UDP-N-acetylglucosamine and UDP-glucuronic acid. To compare th...Read More
Omar O Lozano, Jorge J Mejia, Bernard B Masereel, Olivier O Toussaint, Dominique D Lison, Stéphane S Lucas
The post-translational modification of proteins with N-acetylglucosamine (O-GlcNAc) is involved in the regulation of a wide variety of cellular processes and associated with a number of chronic diseas...Read More
Kiyoko F Aoki-Kinoshita
Although the field of glycome informatics has established several methods, standards and technologies for carbohydrate analysis, the analysis of glycoproteins and other glycoconjugates is still in its...Read More
Zhi Yuan Ma, Yuliya Skorobogatko, Keith Vosseller
In this chapter we describe the application of lectin weak affinity chromatography (LWAC) for the enrichment of peptides modified by O-linked β-N-acetylglucosamine (O-GlcNAc). O-GlcNAc is a single ca...Read More
Bingwu Yu, Hugo van Ingen, Darón I Freedberg
Strong (1)H-(1)H coupling can significantly reduce the accuracy of (1)J(CH) measured from frequency differences in coupled HSQC spectra. Although accurate (1)J(CH) values can be extracted from spectra...Read More
Man-Ching Leung, Paul G Hitchen, Douglas G Ward, Andrew E Messer, Steven B Marston
We studied O-linked β-N-acetylglucosamine (O-GlcNAc) modification of contractile proteins in human heart using SDS-PAGE and three detection methods: specific enzymatic conjugation of O-GlcNAc with UD...Read More
Natalia Mercer, Boopathy Ramakrishnan, Elizabeth Boeggeman, Luke Verdi, Pradman K Qasba
On the basis of the crystal structure of bovine β4Gal-T1 enzyme, mutation of a single amino acid Y289 to L289 (Y289L) changed its donor specificity from Gal to N-acetyl-galactosamine (GalNAc). A chem...Read More
Yi Qian, Heather Flanagan-Steet, Eline van Meel, Richard Steet, Stuart A Kornfeld
UDP-GlcNAc:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase (GlcNAc-1-phosphotransferase) is an α2β2γ2 heterohexamer that mediates the initial step in the formation of the mannose 6-phosph...Read More
Jiajia Bi, Yanfen Li, Fengyun Sun, Anja Saalbach, Claudia Klein, David J Miller, Rex Hess, Romana A Nowak
Basigin (BSG) is a multifunctional glycoprotein that plays an important role in male reproduction since male knockout (KO) mice are sterile. The Bsg KO testis lacks elongated spermatids and mature spe...Read More
Colette Cywes-Bentley, David Skurnik, Tanweer Zaidi, Damien Roux, Rosane B Deoliveira, Wendy S Garrett, Xi Lu, Jennifer O'Malley, Kathryn Kinzel, Tauqeer Zaidi, Astrid Rey, Christophe Perrin, Raina N Fichorova, Alexander K K Kayatani, Tomas Maira-Lit
Microbial capsular antigens are effective vaccines but are chemically and immunologically diverse, resulting in a major barrier to their use against multiple pathogens. A β-(1→6)-linked poly-N-acet...Read More
Mikkel Girke J?rgensen, Maureen K Thomason, Johannes Havelund, Poul Valentin-Hansen, Gisela Storz
Many bacterial small RNAs (sRNAs) regulate gene expression through base-pairing with mRNAs, and it has been assumed that these sRNAs act solely by this one mechanism. Here we report that the multicell...Read More
Kayo Hirose, Yasuo Tsutsumi, Katsuya Tanaka, Shuzo Oshita
We're sorry this abstract is currently not available....Read More
Balyn W Zaro, Howard C Hang, Matthew R Pratt
Glycosylation is an abundant post-translational modification that alters the fate and function of its substrate proteins. To aid in understanding the significance of protein glycosylation, identificat...Read More
Takumi Satoh, Toshitaka Odamaki, Mariko Namura, Takashi Shimizu, Keiji Iwatsuki, Mamoru Nishimoto, Motomitsu Kitaoka, Jin-Zhong Xiao
Lacto-N-biose I (LNB) is a potential factor for the selective growth of bifidobacteria. We previously reported that the species of bifidobacteria predominant in infant intestines might use LNB. We aim...Read More
Tzu-Hsien Wang, Ying-Yin Chen, Hsin-Hung Pan, Feng-Pao Wang, Chung-Hsien Cheng, Wen-Chien Lee
Two sequential enzymes in the production of sialic acids, N-acetyl-D-glucosamine 2-epimerase (GlcNAc 2-epimerase) and N-acetyl-D-neuraminic acid aldolase (Neu5Ac aldolase), were overexpressed as doubl...Read More
Barbara B Choromańska, Magdalena M Luto, S?awomir Dariusz SD Szajda, Napoleon N Waszkiewicz, Alina A K?pka, Jacek J Janica, Jerzy Robert JR Ladny, Jacek J Dadan, Piotr P My?liwiec, Krzysztof K Zwierz
There were approximately 93,060 deaths from cancers in Poland in 2008, and about 105,000 are predicted for the year 2025. Early detection of cancer is a major problem throughout the world, which is wh...Read More