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金刚烷

¥ 64.80

产品编号 A105219 | CAS号 281-23-2 | Aladdin
Adamantane
99.0%
组合的产品项目
货号 规格 库存 价格 数量
A105219-100g 99.0% 上海(>10)
北方(8)
 
A105219-25g 99.0% 上海(>10)
北方(>10)
 
A105219-500g 99.0% 上海(2)
北方(预计3-5个工作日)
 
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属性

折光率 1.568
密度 0.9760
熔点 209-212°C

描述

产品介绍 无味无臭,溶于有机溶剂,不溶于水;有升华性,具有芳香味。容易结晶,具较高的挥发性和化学惰性。
别名 金刚烷 ;金钢烷,三环[3.3.1.13.7]癸烷;tricyclo(3.3.1.1(sup 3,7))decane tricyclo[3.3.1.13,7]decane Diamantane Tricyclo[3.3.1.1]decane pentacyclo[7.3.1.14,12.02,7.06,11]tetradecane diadamantane decahydro-3,5,1,7-[1,2,3,4]butanetetraylnaphthalene
应用 用于生产、合成医药中间体;农药中间体;兽药中间体;橡胶及感光材料领域;信息技术领域。
金刚烷是一种含有10个碳原子和16个氢原子的环状四面体烃,其基本结构是椅形环己烷,它是一种高度对称和非常稳定的化合物。金刚烷具有以下特点:(1)对光非常稳定;(2)润滑力好;(3)极度亲油:(4)基本无臭味,是升华物;(5)虽然反应活性不如苯,但是合成其衍生物非常容易。
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标识符号 GHS09 GHS09
信号词 Warning
安全声明(欧洲) S24/25
警示性声明 P273
危害声明 H400
个人防护设备 Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter
WGK德国 2
Merck Index 149
参考文献
Bo OuYang, Shiqi Xie, Marcelo J Berardi, Xinhao Zhao, Jyoti Dev, Wenjing Yu, Bing Sun, James J Chou
The hepatitis C virus (HCV) has developed a small membrane protein, p7, which remarkably can self-assemble into a large channel complex that selectively conducts cations. We wanted to examine the stru...Read More
Johannes Werzowa, Manfred Hecking, Michael Haidinger, Felix Lechner, Dominik D?ller, Giovanni Pacini, Gunar Stemer, Johannes Pleiner, Sophie Frantal, Marcus D S?emann
New-onset diabetes after transplantation (NODAT) is a serious complication after kidney transplantation affecting graft and patient survival. Currently, no guidelines exist for the management of renal...Read More
Danielle de Lima Avila, Glaucy Rodrigues de Araújo, Maisa Silva, Pedro Henrique de Amorim Miranda, Mirla Fiuza Diniz, Maria Lúcia Pedrosa, Marcelo Eustáquio Silva, Wanderson Geraldo de Lima, Daniela Caldeira Costa
It is believed that oxidative stress plays a role in the pathogenesis of diabetes mellitus. Several strategies have been developed with the objective of minimizing diabetic complications. Among these,...Read More
William Cook, Brian Bryzinski, Jill Slater, Robert Frederich, Elsie Allen
This post hoc analysis sought to assess the efficacy, safety, and tolerability of saxagliptin in patients with type 2 diabetes mellitus and cardiovascular (CV) risk factors or disease (CVD).Data from ...Read More
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Bernard Charbonnel, Anja Schweizer, Sylvie Dejager
As type 2 diabetes mellitus (T2DM) progresses, most patients will require insulin replacement therapy. Whether oral antidiabetic drug (OAD) therapy should be retained when initiating insulin is still ...Read More
Ganesh A Thakur, Shama Bajaj, Carol Paronis, Yan Peng, Anna L Bowman, Lawrence S Barak, Marc G Caron, Demon Parrish, Jeffrey R Deschamps, Alexandros Makriyannis
In previous studies, compound 1 (AM411), a 3-(1-adamantyl) analogue of the phytocannabinoid (-)-Δ(8)-tetrahydrocannabinol (Δ(8)-THC), was shown to have improved affinity and selectivity for the CB1 ...Read More
Deborah Cohen
We're sorry this abstract is currently not available....Read More
Hiranya Pintana, Nattayaporn Apaijai, Nipon Chattipakorn, Siriporn C Chattipakorn
Recent evidence has demonstrated that insulin resistance is related to the development of type 2 diabetes mellitus. Our previous study found that high-fat diet (HFD) consumption caused not only periph...Read More
Ayako Takahashi, Masanori Asakura, Shin Ito, Kyung-Duk Min, Kazuhiro Shindo, Yi Yan, Yulin Liao, Satoru Yamazaki, Shoji Sanada, Yoshihiro Asano, Hatsue Ishibashi-Ueda, Seiji Takashima, Tetsuo Minamino, Hiroshi Asanuma, Naoki Mochizuki, Masafumi Kitakaze
Incretin hormones, including glucagon-like peptide-1 (GLP-1), a target for diabetes mellitus (DM) treatment, are associated with cardioprotection. As dipeptidyl-peptidase IV (DPP-IV) inhibition increa...Read More
Diego Pesce, Yuzhou Wu, Anke Kolbe, Tanja Weil, Andreas Herrmann
One of the barriers to the development of protein therapeutics is effective delivery to mammalian cells. The proteins must maintain a careful balance of polar moieties to enable administration and dis...Read More
V V Zarubaev, P M Anfimov, A A Shtro, A V Garshinina, I A Meleshkina, L A Karpinskaia, K N Kozeletskaia, O I Kiselev
Recent progress of the laboratory in the area of the search and development of novel remedies for prophylaxis and treatment of influenza is reviewed in this work. The data of the study of the anti-vir...Read More
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S S Kyurkchiev, G G Ivanov, V V Manolova
It has been proposed that advanced glycosylated end products (AGEs) are involved in the pathogenesis of vascular damages in both type 1 and type 2 diabetes. Furthermore, it has been assumed that AGEs ...Read More
Marina ?ekutor, Zoran Glasovac, Kata Mlinari?-Majerski
ESI-MS/MS investigation of the mono- and bis(guanylhydrazone) derivatives 1-5 based on adamantane and pentacycloundecane (PCU) skeleton was described. Elimination of neutral guanidine is the most abun...Read More
Anton S Abel, Alexei D Averin, Olga A Maloshitskaya, Evgenii N Savelyev, Boris S Orlinson, Ivan A Novakov, Irina P Beletskaya
Pd-catalyzed amination of isomeric 2,6-, 2,8-, 4,8- and 4,7-dichloroquinolines was studied using adamantane-containing amines in which substituents at the nitrogen atom differ in bulkiness. The select...Read More
We're sorry this abstract is currently not available....Read More
Valentina Lukashevich, Anja Schweizer, James E Foley, Sheila Dickinson, Per-Henrik Groop, Wolfgang Kothny
The purpose of this study was to evaluate the efficacy of vildagliptin 50 mg once daily in patients with severe renal impairment (estimated glomerular filtration rate < 30 mL/min/1.73 m(2)) and lon...Read More
Kenichi Niikura, Naotoshi Sugimura, Yusuke Musashi, Shintaro Mikuni, Yasutaka Matsuo, Shintaro Kobayashi, Keita Nagakawa, Shuko Takahara, Chie Takeuchi, Hirofumi Sawa, Masataka Kinjo, Kuniharu Ijiro
The efficient delivery of hydrophobic drugs into target cells without the use of organic solvents or chemical linkage to delivery carriers is an important theme in the biomedical and pharmaceutical fi...Read More
I G Kapitsa, I I Kokshenev, L N Nerobkova, E A Val'dman, T A Voronina
A single intraperitoneal injection of MPTP neurotoxin (30 mg/kg) in C57BL/6 mice causes desynchronization of EEG with a decrease of theta-1 activity and a growth of beta activity in the interval of 15...Read More
André J Scheen
Dipeptidyl peptidase-4 (DPP-4) inhibitors (gliptins) are oral incretin-based glucose-lowering agents with proven efficacy and safety in the management of type 2 diabetes mellitus (T2DM). In addition, ...Read More
Mika Nabeno, Fumihiko Akahoshi, Hiroyuki Kishida, Ikuko Miyaguchi, Yoshihito Tanaka, Shinichi Ishii, Takashi Kadowaki
In recent years, various dipeptidyl peptidase IV (DPP-4) inhibitors have been released as therapeutic drugs for type 2 diabetes in many countries. In spite of their diverse chemical structures, no com...Read More
Xiaofang Wang, Yuxiang Dong, Sergio Wittlin, Susan A Charman, Francis C K Chiu, Jacques Chollet, Kasiram Katneni, Janne Mannila, Julia Morizzi, Eileen Ryan, Christian Scheurer, Jessica Steuten, Josefina Santo Tomas, Christopher Snyder, Jonathan L Vennerst
To ascertain the structure-activity relationship of the core 1,2,4-trioxolane substructure of dispiro ozonides OZ277 and OZ439, we compared the antimalarial activities and ADME profiles of the 1,2-dio...Read More
Anja Schweizer, James E Foley, Wolfgang Kothny, Bo Ahrén
Due to the progressive nature of type 2 diabetes, many patients need insulin as add-on to oral antidiabetic drugs (OADs) in order to maintain adequate glycemic control. Insulin therapy primarily targe...Read More
Louis H Miller, Hans C Ackerman, Xin-zhuan Su, Thomas E Wellems
Plasmodium falciparum malaria, an infectious disease caused by a parasitic protozoan, claims the lives of nearly a million children each year in Africa alone and is a top public health concern. Eviden...Read More