¥ 87.20

产品编号 A105222 | CAS号 504-29-0 | Aladdin
货号 规格 库存 价格 数量
A105222-100g 99% 上海(>10)
A105222-25g 99% 上海(预计4-8周)
A105222-500g 99% 上海(4)


敏感性 对热、光、湿度敏感
密度 1.1070
熔点 61°C
沸点 210.6°C
存贮条件 储存温度2-8℃,充氩保存


产品介绍 溶于水、乙醇、苯、乙醚、热石油醚,微溶于甲苯。
别名 2-吡啶胺;α-氨基氮杂苯;邻氨基吡啶;2-吡啶基胺;α-氨基吡啶;2-AP ;2-AP; 2-Pyridinamine; 2-Pyridylamine
生化机理 2-Aminopyridine is a compound has been shown to reversibly block voltage-dependent potassium channels, and is also a common impurity from the synthesis of compounds found in hair dye.
应用 A compound has been shown to reversibly block voltage-dependent potassium channels.
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标识符号 GHS06 GHS06
信号词 Danger
风险声明 (欧洲) R21;R25;R36/37/38
安全声明(欧洲) S26;S36/37/39;S45
警示性声明 P261,P280,P301+P310,P305+P351+P338,P312
危害码(欧洲) T
危害声明 H301,H311,H315,H319,H335
个人防护设备 Eyeshields,Faceshields,Gloves,type P2 (EN 143) respirator cartridges
RTECS US1575000
WGK德国 3
Merck Index 473
闪点(摄氏) 92℃
是否危化品 一般危险品
UN代码 2671
Abeer A Faheim, Safaa N Abdou, Zeinab H Abd El-Wahab
Salicylidene (4-aminotoluene-3-sulfonic acid) Schiff base ligand H(2)L, and its binary and ternary Co(II), Ni(II), Cu(II) and Zn(II) complexes using 8-hydroxyquinoline (8-HOqu) and 2-aminopyridine (2-...Read More
Joanna J Romanowska, Micha? M Sobkowski, Agnieszka A Szymańska-Michalak, Krystian K Ko?odziej, Aleksandra A D?browska, Andrzej A Lipniacki, Andrzej A Piasek, Zofia M ZM Pietrusiewicz, Marek M Figlerowicz, Andrzej A Guranowski, Jerzy J Boryski, Jacek J Sta
New synthetic protocol for the preparation of nucleoside 5'-(N-aryl)phosphoramidate monoesters 4 was developed. It consisted of a condensation of the corresponding nucleoside 5'-H-phosphonat...Read More
M M Monier, D M DM Ayad, D A DA Abdel-Latif
The adsorption of Cu(II), Cd(II) and Ni(II) ions from aqueous solution by cross-linked magnetic chitosan-2-aminopyridine glyoxal Schiff's base resin (CSAP) was studied in a batch adsorption syste...Read More
Abdelouahid A Samadi, José J Marco-Contelles, Elena E Soriano, Mónica M Alvarez-Pérez, Mourad M Chioua, Alejandro A Romero, Laura L González-Lafuente, Luis L Gandía, José M JM Roda, Manuela G MG López, Mercedes M Villarroya, Antonio G AG García, Cristóbal
The synthesis, molecular modeling, and pharmacological analysis of new multipotent simple, and readily available 2-aminopyridine-3,5-dicarbonitriles (3-20), and 2-chloropyridine-3,5-dicarbonitriles (2...Read More
Philipp P Ottiger, Samuel S Leutwyler
In more than 60 years of research on molecular excitons, there has been extensive theoretical work but few experimental investigations have rigorously tested the predictions of exciton coupling theori...Read More
Timothy K Lane, Brendan R D'Souza, Janis Louie
Diynes and cyanamides undergo an iron-catalyzed [2 + 2 + 2] cycloaddition to form highly substituted 2-aminopyridines in an atom-efficient manner that is both high yielding and regioselective. This sy...Read More
Chika C Wakita, Kazuya K Honda, Takahiro T Shibata, Mitsugu M Akagawa, Koji K Uchida
We developed a procedure to measure 4-hydroxy-2-nonenal (HNE)-amino acid adducts using the fluorescent probe 2-aminopyridine (2-AP). The method is based on the fact that HNE forms Michael addition-typ...Read More
Fan Zhang, Qiu-Yue Lin, Xiao-Liang Zheng, Ling-Ling Zhang, Qiong Yang, Jia-Ying Gu
Three novel transition metal complexes (Hapy)(2)[M(DCA)(2)]·6H(2)O (M = Mn(II) (1), Ni(II) (2), Cu(II) (3); DCA = demethylcantharate, 7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylate, C(8)H(8)O(5); Hapy ...Read More
Thomas Zengeya, Pankaj Gupta, Eriks Rozners
Peptide nucleic acids containing thymidine and 2-aminopyridine (M) nucleobases form stable and sequence-selective triple helices with double-stranded RNA at physiologically relevant conditions. The M-...Read More
Yoshio Y Araki, Tadao T Bamba, Ken-ichi K Mukaisho, Osamu O Kanauchi, Hiromitsu H Ban, Shigeki S Bamba, Akira A Andoh, Yoshihide Y Fujiyama, Takanori T Hattori, Hiroyuki H Sugihara
The mechanisms responsible for human inflammatory bowel disease remain poorly understood. The pathogenic factors for dextran sulfate sodium (DSS)-induced colitis, one of the experimental animal coliti...Read More
Tadasu Urashima, Sadaki Asakuma, Fiame Leo, Kenji Fukuda, Michael Messer, Olav T Oftedal
Human milk and colostrum contain ~12-13 g/L and ~22-24 g/L of oligosaccharides, respectively. The chemical structures of >100 human milk oligosaccharides (HMO) have been characterized to date. ...Read More
Ewa D Raczyńska, Tomasz M St?pniewski, Katarzyna Kolczyńska
Quantum-chemical calculations {DFT(B3LYP)/6-311+G(d,p)} were performed for all possible tautomers (aromatic and nonaromatic) of neutral 2- and 4-aminopyridines and their oxidized and reduced forms. On...Read More
Philipp P Ottiger, Samuel S Leutwyler, Horst H K?ppel
The S(1)/S(2) state exciton splittings of symmetric doubly hydrogen-bonded gas-phase dimers provide spectroscopic benchmarks for the excited-state electronic couplings between UV chromophores. These h...Read More
Daniela P DP Gouvêa, Valéria D O VD Bare?o, Juliano J Bosenbecker, Bruna B BB Drawanz, Patrícia D PD Neuenfeldt, Geonir M GM Siqueira, Wilson W Cunico
The efficient multicomponent synthesis of thiazolidinones from the reaction of arenealdehydes, mercaptoacetic acid and 2-picolilamine or 2-aminopyridine under ultrasound irradiation are reported. The ...Read More
Kayo K Hasehira, Nobumitsu N Miyanishi, Wataru W Sumiyoshi, Jun J Hirabayashi, Shin-ichi S Nakakita
Rare sugars are monosaccharides that are found in relatively low abundance in nature. Herein, we describe a strategy for producing rare aldohexoses from ketohexoses using the classical Lobry de Bruyn-...Read More
Mostafa Najafi, Rasoul Mehdipour
A molecularly imprinted polymer-based potentiometric sensor was fabricated for determination of 2-aminopyridine (2-AP). The electroactive component is the 2-APH(+) . To form this specie the determinat...Read More
A general and facile one-pot amination procedure for the synthesis of 2-aminopyridines from the corresponding pyridine-N-oxides is presented as a mild alternative to S(N)Ar chemistry. A variety of ami...Read More
Honggen Wang, Yong Wang, Changlan Peng, Jiancun Zhang, Qiang Zhu
A novel and efficient synthesis of pyrido[1,2-a]benzimidazoles through direct intramolecular aromatic C-H amination of N-aryl-2-aminopyridines has been developed. The reaction, cocatalyzed by Cu(OAc)(...Read More
Kazusa K Nishiyama, Atsushi A Yamada, Miki M Takahashi, Tomoharu T Takeuchi, Ken-ichi K Kasai, Susumu S Kobayashi, Hideaki H Natsugari, Hideyo H Takahashi
To search for the endogenous glyco-epitope in Caenorhabditis elegans, we synthesized labeled Galbeta1-3Fuc and Galbeta1-4Fuc and examined their binding affinity for C. elegans galectin LEC-6 using fro...Read More
Xiaoqing Xin, Peng Huang, Dexuan Xiang, Rui Zhang, Fengyu Zhao, Ning Zhang, Dewen Dong
A facile and efficient synthetic route to multi-substituted 2-aminopyridines has been developed via a formal [5C + 1N] annulation of readily available 2,4-pentadienenitriles with hydroxylamine (NH(2)O...Read More
Suman K Vodnala, Thomas Lundb?ck, Birger Sj?berg, Richard Svensson, Martin E Rottenberg, Lars G J Hammarstr?m
New drugs for the treatment of human African trypanosomiasis are urgently needed. A number of 2-aminopyrazines/2-aminopyridines were identified as promising leads following a focused screen of 5,500 c...Read More
Renee R Webber, Glenn H GH Penner
Deuterium magic angle spinning (MAS) NMR spectroscopy and quantum chemical calculations are used to investigate organic solids in which inequivalent hydrogen bonds are present. The use of (2)H MAS all...Read More
Tris(trimethylsilyl)silane and azobis(cyclohexanenitrile) promoted the easy intramolecular arylation of aryl bromopyridine carbamates through a radical [1,6] ipso substitution process. These substrate...Read More
Yue-Jie Ai, Feng Zhang, Gang-Long Cui, Yi Luo, Wei-Hai Fang
2-Aminopyridine dimer has frequently been used as a model system for studying photochemistry of DNA base pairs. We examine here the relevance of 2-aminopyridine dimer for a Watson-Crick adenine-thymin...Read More
Jianguo Fang, Haitao Ji, Graham R Lawton, Fengtian Xue, Linda J Roman, Richard B Silverman
A common dichotomy exists in inhibitor design: should the compounds be designed to block the enzymes of animals in the preclinical studies or to inhibit the human enzyme? We report that a single mutat...Read More
Ullvi Bluhm, Jean-Luc Boucher, Uwe Buss, Bernd Clement, Friederike Friedrich, Ulrich Girreser, Dieter Heber, Thanh Lam, Michel Lepoivre, Mojgan Rostaie-Gerylow
A series of new 3-aroylpyrido[1,2-a]pyrimidines were synthesized from aryl methyl ketones in a simple two-step procedure and evaluated as nitric oxide synthases (NOS) inhibitors. In order to perform a...Read More
Takaaki T Miura, Takaaki A TA Fukami, Kiyoshi K Hasegawa, Naomi N Ono, Atsushi A Suda, Hidetoshi H Shindo, Dong-Oh DO Yoon, Sung-Jin SJ Kim, Young-Jun YJ Na, Yuko Y Aoki, Nobuo N Shimma, Takuo T Tsukuda, Yasuhiko Y Shiratori
Heat shock protein 90 (Hsp90) is a molecular chaperone which regulates maturation and stabilization of its substrate proteins, known as client proteins. Many client proteins of Hsp90 are involved in t...Read More
Zhang-Gao Le, Zong-Bo Xie, Jian-Ping Xu
One-pot synthesis of 2-phenylimidazo[1,2-α]pyridines from acetophenone, [Bmim]Br(3) and 2-aminopyridine under solvent-free conditions in the presence of Na(2)CO(3), gave the corresponding 2-p...Read More