展开

两性霉素B

¥ 199.00

产品编号 A105482 | CAS号 1397-89-3 | Aladdin
Amphotericin B
80%,750 μg/mg
组合的产品项目
货号 规格 库存 价格 数量
A105482-1g 80%,750 μg/mg 上海(>10)
北方(预计3-5个工作日)
 
A105482-250mg 80%,750 μg/mg 上海(>10)
北方(预计3-5个工作日)
 
A105482-5g 80%,750 μg/mg 上海(8)
北方(预计3-5个工作日)
 
客户看了后又看了下面的产品

属性

敏感性 对光和湿度敏感
熔点 >170°C
存贮条件 储存温度2-8℃

描述

产品介绍 溶于DMSO,水中溶解度:<0.1 g/100 mL ,21°C
别名 ;Fungizone; Amphotericin B from Streptomyces sp; Amphotericin B solubilized
应用 多烯类抗真菌药物。本品与真菌细胞膜上的甾醇结合,损伤膜的通透性,导致菌细胞内钾离子、核苷酸、氨基酸等外漏,破坏正常代谢而起抑菌作用。
编写您自己的评论
只有注册的用户才可以写评论。请 登录 创建帐户
个人防护设备 Eyeshields,Gloves,half-mask respirator (EU),half-mask respirator (US),multi-purpose combination respirator cartridge (US)
参考文献
Yukio Okada, Kotapola G Imendra, Toshihiro Miyazaki, Hitoshi Hotokezaka, Rie Fujiyama, Kazuo Toda
Elevation of extracellular Ca(2+) concentration induces intracellular Ca(2+) signaling in parathyroid cells. The response is due to stimulation of the phospholipase C/Ca(2+) pathways, but the direct m...Read More
Mariusz Dyl?g, Pawe? Lis, Katarzyna Nied?wiecka, Young H Ko, Peter L Pedersen, Andre Goffeau, Stanis?aw U?aszewski
We have investigated the antifungal activity of the pyruvic acid analogue: 3-bromopyruvate (3-BP). Growth inhibition by 3-BP of 110 strains of yeast-like and filamentous fungi was tested by standard s...Read More
Johannes Zander, Silke Besier, Stephan H Saum, Faramarz Dehghani, Stefan Loitsch, Volker Brade, Thomas A Wichelhaus
Thymidine-dependent small-colony variants (SCVs) of Staphylococcus aureus are frequently associated with persistent and recurrent infections in cystic fibrosis patients. The phenotypic appearance of S...Read More
Andrew M Borman, Rebecca Petch, Christopher J Linton, Michael D Palmer, Paul D Bridge, Elizabeth M Johnson
In 2005, Candida nivariensis, a yeast species genetically related to Candida glabrata, was described following its isolation from three patients in a single Spanish hospital. Between 2005 and 2006, 16...Read More
Liviu A Sicinschi, Pelayo Correa, Richard M Peek, M Constanza Camargo, Alberto Delgado, M Blanca Piazuelo, Judith Romero-Gallo, Luis E Bravo, Barbara G Schneider
cagA-positive and vacA s1 and m1 genotypes of Helicobacter pylori are associated with an elevated risk of gastric cancer (GC). We determined these genotypes using paraffin-embedded gastric biopsy spec...Read More
Ulisse Garbin, Anna Fratta Pasini, Chiara Stranieri, Stefania Manfro, Chiara Mozzini, Veronica Boccioletti, Andrea Pasini, Mattia Cominacini, Stefano Evangelista, Luciano Cominacini
The endothelium plays a key role in the development of atherogenesis and its inflammatory and proliferative status influences the progression of atherosclerosis. The aim of this study is to compare th...Read More
R Scott Pearsall, Ernesto Canalis, Milton Cornwall-Brady, Kathryn W Underwood, Brendan Haigis, Jeffrey Ucran, Ravindra Kumar, Eileen Pobre, Asya Grinberg, Eric D Werner, Vaida Glatt, Lisa Stadmeyer, Deanna Smith, Jasbir Seehra, Mary L Bouxsein
Diseases that affect the regulation of bone turnover can lead to skeletal fragility and increased fracture risk. Members of the TGF-beta superfamily have been shown to be involved in the regulation of...Read More
James H Keith, Tresa S Fraser, Malcolm J Fraser
The piggyBac transposable element is a popular tool for germ-line transgenesis of eukaryotes. Despite this, little is known about the mechanism of transposition or the transposase (TPase) itself. A th...Read More
Tobias M TM Lindig, Vinod V Kumar, Ron R Kikinis, Steve S Pieper, Falk F Schr?dl, Winfried L WL Neuhuber, Axel A Brehmer
We have compared the three-dimensional (3D) morphology of stubby and spiny neurons derived from the human small intestine. After immunohistochemical triple staining for leu-enkephalin (ENK), vasoactiv...Read More
Theresa Meickle, Susan Matthew, Cliff Ross, Hendrik Luesch, Valerie Paul
Bioassay-guided fractionation of a non-polar extract of Lyngbya cf. polychroa resulted in the isolation of the cytotoxic desacetylmicrocolin B (1) as well as the known compounds microcolins A (2) and ...Read More
Brice Enjalbert, Anna Rachini, Govindsamy Vediyappan, Donatella Pietrella, Roberta Spaccapelo, Anna Vecchiarelli, Alistair J P Brown, Christophe d'Enfert
Real-time monitoring of the spatial and temporal progression of infection/gene expression in animals will contribute greatly to our understanding of host-pathogen interactions while reducing the numbe...Read More
Dong H DH Hwang, Byung G BG Kim, Eun J EJ Kim, Seung I SI Lee, In S IS Joo, Haeyoung H Suh-Kim, Seonghyang S Sohn, Seung U SU Kim
Contusive spinal cord injury is complicated by a delayed loss of oligodendrocytes, resulting in chronic progressive demyelination. Therefore, transplantation strategies to provide oligodendrocyte line...Read More
Bradley P Dixon, Jeff Henry, Brian J Siroky, Albert Chu, Pamela A Groen, John J Bissler
Children with complex urogenital anomalies often require bladder reconstruction. Gastrointestinal tissues used in bladder augmentations exhibit a greatly increased risk of malignancy, and the bladder ...Read More
Grasiella Andriani, Anne-Danielle C Chessler, Gilles Courtemanche, Barbara A Burleigh, Ana Rodriguez
Novel technologies that include recombinant pathogens and rapid detection methods are contributing to the development of drugs for neglected diseases. Recently, the results from the first high through...Read More
Jeremy N Day, Tran T H Chau, David G Lalloo
We're sorry this abstract is currently not available....Read More
Anil Bhansali, Sambit Das, Pinaki Dutta, Rama Walia, Uma Nahar, S K Singh, P Vellayutham, Shanmugasundar Gopal
Histoplasmosis has been sporadically reported from India. Though asymptomatic adrenal involvement has been described in patients with disseminated histoplasmosis; isolated adrenal involvement with adr...Read More
Adam Zanation, David Fleischman, Sai H Chavala
We're sorry this abstract is currently not available....Read More
The combined action of polyene macrolide antibiotic amphotericin B and styryl dye RH 421 in model lipid membranes and in yeast Saccharomyces cerevisiae has been studied. RH 421 insertion inti the ergo...Read More
Michel Monod, Massimo Lurati, Florence Baudraz-Rosselet
PCR methods are reliable and suitable to in situ identify dermatophytes, yeasts and non dermatophyte moulds (NDM) in onychomycosis. Onychomycosis insensitive to standard treatment with topical agents ...Read More
Dale M Walker, J Patrick O'Neill, Frederick L Tyson, Vernon E Walker
The events or factors that lead from normal cell function to conditions and diseases such as aging or cancer reflect complex interactions between cells and their environment. Cellular stress responses...Read More
Dale M Walker, Janice A Nicklas, Vernon E Walker
Cellular stress responses consist of a complex network of pathways and linked processes that, when perturbed, are postulated to have roles in the pathogenesis of various human diseases. To assess the ...Read More
Jeremy N Day, Tran T H Chau, Marcel Wolbers, Pham P Mai, Nguyen T Dung, Nguyen H Mai, Nguyen H Phu, Ho D Nghia, Nguyen D Phong, Cao Q Thai, Le H Thai, Ly V Chuong, Dinh X Sinh, Van A Duong, Thu N Hoang, Pham T Diep, James I Campbell, Tran P M Sieu, Stephe
Combination antifungal therapy (amphotericin B deoxycholate and flucytosine) is the recommended treatment for cryptococcal meningitis but has not been shown to reduce mortality, as compared with ampho...Read More
Ankur Gupta, Dipankar M Bhowmik, Pavitra M Dogra, Satish Mendonca, Amit Gupta
We herein report a renal allograft recipient five years post transplant who had bilateral lung abscesses. The abscess grew Candida tropicalis on bronchoalveolar lavage. The patient was administered am...Read More
John E Linley
Perforated whole-cell patch-clamp is a variant of the patch-clamp technique used to measure the sum activity of ion channels in the plasma membrane of a single cell. Its defining feature is that elect...Read More
Bao-Di Dai, Yan Wang, Lan-Xue Zhao, De-Dong Li, Ming-Bang Li, Yong-Bing Cao, Yuan-Ying Jiang
Candida?albicans is the most common opportunistic fungal pathogen and its apoptosis is inducible by environmental stress. Based on our previous finding that transcription factor Cap1p was involved in ...Read More
Daisuke Sasai, Yoichiro Okubo, Takao Ishiwatari, Takashi Sugita, Takehiko Kaneko, Somay Yamagata Murayama, Tsuyoshi Shimamura, Minoru Shinozaki, Chikako Hasegawa, Aki Mitsuda, Naobumi Tochigi, Megumi Wakayama, Tetsuo Nemoto, Kazutoshi Shibuya
The efficacy of polyene macrolides to treat experimental Trichosporon bloodstream infection was evaluated by histopathological examination and viable cell counts in the kidneys of infected mice. Viabl...Read More
Gurpreet Singh, Meer-Taher Shabani-Rad, Otto G Vanderkooi, Joseph V Vayalumkal, Susan M Kuhn, Gregory M T Guilcher, MacGregor Steele
Hemophagocytic lymphohistiocytosis (HLH) associated with visceral leishmaniasis (VL) is a very rare phenomenon. We report the first known North American case in a 21 month old boy. He was initially di...Read More
Benoit Pilmis, Fanny Lanternier, Olivier Lortholary
Mucormycosis is a life-threatening invasive fungal infection that arises among immunocompromised patients (haematological malignancies, solid organ transplantation, diabetes mellitus). The most freque...Read More
S Sarma, N Kumar, S Sharma, D Govil, T Ali, Y Mehta, A Rattan
We're sorry this abstract is currently not available....Read More
Masaki Fujita, Jun Yanagisawa, Masafumi Hiratsuka, Takeshi Shiraishi, Ryosuke Hirano, Takemasa Matsumoto, Motokimi Shiraishi, Akinori Iwasaki, Kentaro Watanabe
We report a case of pulmonary aspergillosis in lung transplant recipient who was successfully treated with inhalation administration of anti-fungal agent. The case was 33-year-old female. Two years ag...Read More
Bao Zhang, Chunjuan Dong, Qingmao Shang, Yuzhu Han, Pinglan Li
Bacillomycin L, a natural iturinic lipopeptide produced by Bacillus amyloliquefaciens, is characterized by strong antifungal activities against a variety of agronomically important filamentous fungi i...Read More
Surjit Lidder, A Tasleem, S Masterson, R W J Carrington
Infection is the third commonest cause of total hip arthroplasty failure. Infections of the hip with Candida species are extremely rare with only a few reports in the literature. A case of a 76-year-o...Read More
We're sorry this abstract is currently not available....Read More
Tzu-Sen Yang, Keng-Liang Ou, Pei-Wen Peng, Bing-Chun Liou, Wei-Ting Wang, Yuan-Chen Huang, Chung-Min Tsai, Ching-Hua Su
Recently, the structure-function relationships between amphotericin B (AmB) and ergosterol have been solved using synthetic techniques that require a mycosamine-mediated direct binding interaction bet...Read More
John R Perfect
We're sorry this abstract is currently not available....Read More
Dima Youssef, Brijesh Raval, Adel El-Abbassi, Paras Patel
Blastomycosis rarely presents in pregnancy. Pregnancy is a state of partial immunodeficiency that predisposes to blastomyces infection, especially in endemic areas. Blastomycosis in pregnancy has been...Read More
Afaq Ahmad Khan, Ambuj Garg, Shashi Dhawan, Pankaj Kumar Agarwal, Fouzia Siraj, Shyam Aggarwal
Non-Hodgkin's lymphoma (NHL) is predominantly a disease of lymph nodes, but extranodal involvement is not very uncommon. Palatal involvement by NHL is rare. Mucormycosis is a devastating fungal i...Read More
D Standaert, F Laurent, S Jonckheere, J M Scheiff, B Vandercam, J C Yombi
Leishmaniasis, an intracellular protozoal infection in which tissue macrophages are targeted, is transmitted by female sandfly bite and occurs in 98 countries. Visceral leishmaniasis (VL) is the clini...Read More
Evelien A N Oostdijk, Anne Marie G A de Smet, Marc J M Bonten, Marc J M Bonten
We're sorry this abstract is currently not available....Read More
Shankar P Parajuli, Georgi V Petkov
Large conductance voltage- and Ca(2+)-activated K(+) (BK) channels are key regulators of detrusor smooth muscle (DSM) contraction and relaxation during urine voiding and storage. Here, we explored whe...Read More
Israel Molina, Roser Fisa, Cristina Riera, Vicen? Falcó, Aleix Elizalde, Fernando Salvador, Manuel Crespo, Adrian Curran, Paulo López-Chejade, Silvia Tebar, Santiago Pérez-Hoyos, Esteban Ribera, Albert Pahissa
Abstract. Molecular methods have been proposed as an alternative tool for the diagnosis of visceral leishmaniasis (VL), but no data are available regarding use for monitoring clinical outcome. A prosp...Read More
Fran?ois L Mayer, Duncan Wilson, Bernhard Hube
Systemic infections of humans with the fungal pathogen Candida albicans are associated with a high mortality rate. Currently, efficient treatment of these infections is hampered by the relatively low ...Read More
Boris Musset, Deri Morgan, Vladimir V Cherny, Donald W MacGlashan, Larry L Thomas, Eduardo Ríos, Thomas E DeCoursey
Eosinophils and other phagocytes use NADPH oxidase to kill bacteria. Proton channels in human eosinophils and neutrophils are thought to sustain NADPH oxidase activity, and their opening is greatly en...Read More
George Dimopoulos, Aristea Velegraki, Matthew E Falagas
This study retrospectively reviews the susceptibility of 135 baseline ICU candidemia isolates (from 1997 to 2007) to nine antifungals as determined by the AFST-EUCAST microdilution method and identifi...Read More
Elodie Fino, Jean-Michel Deniau, Laurent Venance, Olivier Jacques Manzoni
Action potentials are thought to be determinant for the induction of long-term synaptic plasticity, the cellular basis of learning and memory. However, neuronal activity does not lead systematically t...Read More
Barbara Zonta, Anne Desmazieres, Arianna Rinaldi, Steven Tait, Diane L Sherman, Matthew F Nolan, Peter J Brophy
The axon initial segment (AIS) is critical for the initiation and propagation of action potentials. Assembly of the AIS requires interactions between scaffolding molecules and voltage-gated sodium cha...Read More