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抑肽酶 来源于牛肺

产品编号 A105534 | CAS号 9087-70-1 | 阿拉丁
Aprotinin from bovine lung
冻干粉, 3-8 TIU/mg
  • 分子式 C284H432N84O79S7
  • 分子量6511.44
  • Beilstein号
  • EC号
  • MDL号 MFCD00162935
  • PubChem编号
组合的产品项目
货号 规格 库存 价格 数量
A105534-100mg 冻干粉, 3-8 TIU/mg 上海(5)
北方(预计3-5个工作日)
 
A105534-25mg 冻干粉, 3-8 TIU/mg 上海(6)
北方(4)
 
A105534-5mg 冻干粉, 3-8 TIU/mg 上海(2)
北方(3)
 
A105534-500mg 冻干粉, 3-8 TIU/mg 上海(预计3-7周)
北方(预计3-7周)
 
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属性

密度 1.1300
存贮条件 储存温度2-8℃

描述

产品介绍 Aprotinin is a single chain polypeptide (58 amino-acids) crosslinked by three disulfide bridges, showing competitive and reversible inhibiton of proteolytic and esterolytic activity. Aprotinin forms stable complexes and blocks the active sites of serine protease enzymes. Binding is reversible with most aprotinin-protease complexes dissociating at pH >10 or < 3 (optimum pH 5-7); effective concentration is equimolar with protease. Used as a proteolytic inhibitor in radioimmunoassays of polypeptide hormones.
别名 抑肽酶; Trasylol 胰蛋白酶抑制剂(碱性);Trypsin inhibitor (basic)
生化机理 Aprotinin is a competitive serine protease inhibitor that forms stable complexes with and blocks the active sites of enzyme. This binding is reversible, and most aprotinin-protease complexes will dissociate at extreme pH levels >10 or <3. Structurally, Aprotinin is a monomeric globular protein derived from bovine lung that consists of 58 amino acids, arranged in a single polypeptide chain with three crosslinking disulfide bridges.
备注 另一个常用的活性单位是 KIU(激肽释放酶抑制剂单位)。
1 TIU ~ 1,300 KIU。
应用 Aprotinin is largely used as an inhibitor of trypsin.
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标识符号 GHS08 GHS08
信号词 Danger
风险声明 (欧洲) R42/43;
安全声明(欧洲) S36;
警示性声明 P261,P280,P342+P311
危害码(欧洲) Xn
危害声明 H317,H334
WGK德国 3