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溴化乙酰胆碱

产品编号 A106023 | CAS号 66-23-9 | Aladdin
Acetylcholine bromide
98%
组合的产品项目
货号 规格 库存 价格 数量
A106023-100g 98% 上海(货期不确定)
北方(货期不确定)
 
缺货
A106023-25g 98% 上海(货期不确定)
北方(货期不确定)
 
缺货
A106023-5g 98% 上海(货期不确定)
北方(货期不确定)
 
缺货
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属性

密度 1.0800
熔点 142-146°C
存贮条件 储存温度2-8°C

描述

产品介绍 易吸湿。对光和空气敏感。易溶于冷水,溶于乙醇,几乎不溶于乙醚和苯。在热水或碱性溶液中分解。在PH4时较稳定。,测定乙酰胆碱脂酶的抵物。
别名 溴化乙酰胆碱 ;乙酰溴化胆碱,乙酰基溴化胆碱;2-(Acetyloxy)-N,N,N-trimethylethanaminium bromide ACH
应用 神经突触中的内在的神经传递素,能诱导肌肉收缩,肌纤维膜潜在的扩增行动。
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标识符号 GHS07 GHS07
信号词 Warning
风险声明 (欧洲) R36/37/38
安全声明(欧洲) S26;S36
警示性声明 P261,P305+P351+P338
危害码(欧洲) Xi
危害声明 H315,H319,H335
个人防护设备 dust mask type N95 (US),Eyeshields,Gloves
RTECS FZ9680000
WGK德国 3
Merck Index 86
参考文献
Rosalyn J Moran, Pablo Campo, Mkael Symmonds, Klaas E Stephan, Raymond J Dolan, Karl J Friston
Acetylcholine (ACh) is a neuromodulatory transmitter implicated in perception and learning under uncertainty. This study combined computational simulations and pharmaco-electroencephalography in human...Read More
Rogier B Poorthuis, Bernard Bloem, Matthijs B Verhoog, Huibert D Mansvelder
Adolescence is a period in which the developing prefrontal cortex (PFC) is sensitive to maladaptive changes when exposed to nicotine. Nicotine affects PFC function and repeated exposure to nicotine du...Read More
Hussein M Salahdeen, Gbolahan O Idowu, Babatunde A Murtala
Tridax procumbens leaf extract induced aortic relaxation in a concentration-dependent manner, for both phenylephrine (PE) and KCl- induced contractions in isolated rat aortic rings. The relaxation eff...Read More
Hilary A Petrash, Alison Philbrook, Marian Haburcak, Belinda Barbagallo, Michael M Francis
Heterogeneity in the composition of neurotransmitter receptors is thought to provide functional diversity that may be important in patterning neural activity and shaping behavior (Dani and Bertrand, 2...Read More
Effects of some inhibitors of serine/threonine and tyrosine protein phosphatases on the depression and spontaneous recovery of the acetylcholine-induced inward current (ACh-current) in command Helix n...Read More
M R Khara, S I Pavlovych, V M Mykha?liuk
In experiments on sexually mature rats we studied specific cholinergic regulations of the heart and the degree of its structural damage in hypothyroidism, depending on gender and hormone-productive ac...Read More
Haipeng Zhu, Bula J Bhattacharyya, Hong Lin, Christopher M Gomez
Cholinergic overactivity in diseases of neuromuscular transmission elicits a retrograde signal resembling homeostatic synaptic plasticity that downregulates transmitter release. Understanding this com...Read More
Ming Zhao, Xi He, Xue-Yuan Bi, Xiao-Jiang Yu, W Gil Wier, Wei-Jin Zang
Myocardial ischemia/reperfusion (I/R) induces inflammatory response that may lead to remote vascular injury. Vagal nerve elicits the cholinergic anti-inflammatory pathway by activating α7 nicotinic a...Read More
Yingchuan B Qi, Michelle D Po, Patrick Mac, Taizo Kawano, Erik M Jorgensen, Mei Zhen, Yishi Jin
Excitatory acetylcholine motor neurons drive Caenorhabditis elegans locomotion. Coordinating the activation states of the backward-driving A and forward-driving B class motor neurons is critical for g...Read More
Shira Sheen-Ophir, Yehosua Almog
BotuLinum toxin A (Botox, Allegan) is a potent neurotoxin that blocks the release of acetylcholine at the neuromuscular junction of cholinergic nerves. Botulinum toxin was introduced to clinical medic...Read More
Anna M J Thijs, Carla M L van Herpen, Fred C G J Sweep, Anneke Geurts-Moespot, Paul Smits, Winette T A van der Graaf, Gerard A Rongen
Angiogenesis inhibitors have remarkably improved the outcome of patients with several types of cancer. Hypertension is the most reported side effect of angiogenesis inhibitors interfering with vascula...Read More
Mariona Pinart, Min Zhang, Feng Li, Farhana Hussain, Jie Zhu, Coen Wiegman, Bernard Ryffel, Kian Fan Chung
IL-17A induces the release of pro-inflammatory cytokines and of reactive oxygen species which could lead to neutrophilic inflammation. We determined the role of IL-17 receptor (IL-17R) signalling in o...Read More
O V Tyapkina, A I Malomouzh, L F Nurullin, E E Nikolsky
We're sorry this abstract is currently not available....Read More
Studies results of gravity unloading influence on spinal control system of muscle structure and functions are summarized. It was shown that demyelization of axons due to reduction of genes expression ...Read More
William M Howe, Anne S Berry, Jennifer Francois, Gary Gilmour, Joshua M Carp, Mark Tricklebank, Cindy Lustig, Martin Sarter
We previously reported involvement of right prefrontal cholinergic activity in veridical signal detection. Here, we first recorded real-time acetylcholine release in prefrontal cortex (PFC) during spe...Read More
Vincent Douchamps, Ali Jeewajee, Pam Blundell, Neil Burgess, Colin Lever
The formation of new memories requires new information to be encoded in the face of proactive interference from the past. Two solutions have been proposed for hippocampal region CA1: (1) acetylcholine...Read More
Model of chronic obstructive pulmonary disease (COPD) was induced in rats by nitrogen dioxide inhalation for 60 days. The effect of reagents-vasodilators on the isolated pulmonary arteries with a diam...Read More
Wei Wang, Yan Deng, Song Li, Hongna Liu, Zhuoxuan Lu, Liming Zhang, Lin Lin, Lijian Xu
A novel type of acetylcholine electrochemical biosensor was successfully fabricated by dropping beta-cyclodextrin solution, acetylcholinesterase solution and Nafion-methanol solution to the homemade n...Read More
Jorge E Nieto, Betina Morales, Sawsan Z Yamout, Scott D Stanley, Faye A Harmon, Jack R Snyder
To determine the response to neostigmine of the contractile activity of the jejunum and pelvic flexure and the effects of a continuous rate infusion (CRI) of neostigmine in horses.7 adult horses and t...Read More
Yasutaka Kurata, Ichiro Hisatome, Mamoru Tanida, Toshishige Shibamoto
To elucidate the effects of hyperpolarization-activated current If on robustness of sinoatrial node (SAN) pacemaking in connection with intracellular Na(+) concentration (Nai) changes, we theoreticall...Read More
Duygu Selcen, Xin-Ming Shen, Margherita Milone, Joan Brengman, Kinji Ohno, Feza Deymeer, Richard Finkel, Julie Rowin, Andrew G Engel
To identify patients with GFPT1-related limb-girdle myasthenia and analyze phenotypic consequences of the mutations.We performed genetic analysis, histochemical, immunoblot, and ultrastructural studie...Read More
Yuhua Zhang, Xiaoming Wang, Yun Wang, Yan Liu, Min Xia
Atherosclerosis is accelerated in diabetes mellitus mainly due to the reduced availability and function of endothelial progenitor cells (EPCs). The purpose of this study was to determine the protectiv...Read More
Sieneke Labruijere, E Leonie A F van Houten, René de Vries, Usha M Musterd-Bagghoe, Ingrid M Garrelds, Piet Kramer, A H Jan Danser, Carlos M Villalón, Jenny A Visser, Antoinette Maassen Van Den Brink
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of there productive age, but the exact pathophysiological mechanisms involved remain unclear. Cardiovascular disease ris...Read More
Kirstine Calloe, Robert Goodrow, S?ren-Peter Olesen, Charles Antzelevitch, Jonathan M Cordeiro
Acetylcholine (ACh) release from the vagus nerve slows heart rate and atrioventricular conduction. ACh stimulates a variety of receptors and channels, including an inward rectifying current [ACh-depen...Read More
Marie Briet, Tlili Barhoumi, Muhammad Oneeb Rehman Mian, Cristina Sierra, Pierre Boutouyrie, Michael Davidman, David Bercovitch, Sharon J Nessim, Gershon Frisch, Pierre Paradis, Mark L Lipman, Ernesto L Schiffrin
Recent studies have raised concern about the safety of erythropoiesis-stimulating agents because of evidence of increased risk of hypertension and cardiovascular morbidity and mortality in chronic kid...Read More
Yoshihiko Kakinuma, Masayuki Tsuda, Kayo Okazaki, Tsuyoshi Akiyama, Mikihiko Arikawa, Tatsuya Noguchi, Takayuki Sato
Murine and human ventricular cardiomyocytes rich in acetylcholine (Ach) receptors are poorly innervated by the vagus, compared with whole ventricular innervation by the adrenergic nerve. However, vaga...Read More
Giovanna Paolone, Christopher C Angelakos, Paul J Meyer, Terry E Robinson, Martin Sarter
Some rats [sign-trackers (STs)] are especially prone to attribute incentive salience to reward cues, relative to others [goal-trackers (GTs)]. Thus, reward cues are more likely to promote maladaptive ...Read More
Alessandro Furlan, Moritz Lübke, Igor Adameyko, Francois Lallemend, Patrik Ernfors
The sympathetic nervous system relies on distinct populations of neurons that use noradrenaline or acetylcholine as neurotransmitter. We show that fating of the sympathetic lineage at early stages res...Read More
L F Nurullin, A N Tsentsevitsky, A I Malomouzh, E E Nikolsky
We're sorry this abstract is currently not available....Read More
M S Moraes, S R Leite
We report the in vitro inhibitory effect of very low concentrations of aluminum salts (IC50 = 4.1 x 10(-12 M) on bovine brain acetylcholinesterase (AChE). The enzymatic assays were performed using ace...Read More
W Han, S Zhang, D Han, S Jiang, W Yang
To better understand the cholinergic receptors in vestibular hair cells (VHC) and their subtypes, and to investigate the effects of cholinergic agonists on intracellular calcium concentration ([Ca2+]i...Read More
Jipei Yuan, Jianyuan Yin, Erkang Wang
Capillary electrophoresis with electrochemiluminescene detection was used to characterize procaine hydrolysis as a probe for butyrylcholinesterase by in vitro procaine metabolism in plasma with butyry...Read More