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二苯基硼酸-2-氨基乙酯

产品编号 A106408 | CAS号 524-95-8 | 阿拉丁
2-Aminoethyl diphenylborinate
98%
组合的产品项目
货号 规格 库存 价格 数量
A106408-1g 98% 上海(>10)
北方(预计3-5个工作日)
 
A106408-25g 98% 上海(预计3-7周)
北方(预计3-7周)
 
A106408-5g 98% 上海(预计3-7周)
北方(预计3-7周)
 
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属性

敏感性 光及湿度敏感
密度 1.0400
熔点 190-194°C
存贮条件 储存温度-20°C;充氩保存

描述

产品介绍 2-APB is a transient receptor potential (TRP) activator. The compound also directly blocks the mitochondrial permeability transition pore, sarco/endoplasmic reticulum Ca2+-ATPase pumps, and native store operated channels, as well as other ion channels. 2-APB does not activate the subfamily transient receptor potential vanilloids (TRPVs) TRPV4, TRPV5, and TRPV6, but can activate VR1 (TRPV1), VRL-1 (TRPV2), and TRPV3. 2-ABP was first used as an inhibitor of IP3R (inositol 1,4,5-triphosphate receptor) with the ability to permeate the membrane. 2-ABP can induce Ca2+entry without activating exocytosis. In pancreatic acinar cells 2-ABP can inhibit calcium mobilization. 2-APB is an activator of Orai3.
别名 二苯基硼酸2-氨基乙酯;2-氨基乙基二苯硼酸酯;2-氨基乙基联苯基硼酸酯;2-氨基乙酯二苯基硼酸;2-氨基乙基联苯基硼酸酯;二苯基硼酸;(2-Aminoethoxy)diphenylborane;2-Aminoethyl diphenyl borate;Diphenylboric acid 2-aminoethyl ester;2-APB
应用 用于黄酮类化合物的密度测定。膜渗透调控因子,调控细胞间IP3诱导的钙离子释放。
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安全声明(欧洲) S24/25;
个人防护设备 Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter
WGK德国 3
参考文献
Thomas Voets, Karel Talavera, Grzegorz Owsianik, Bernd Nilius
Drosophila melanogaster flies carrying the trp (transient receptor potential) mutation are rapidly blinded by bright light, because of the absence of a Ca2+-permeable ion channel in their photorecepto...Read More
T T Maruyama, T T Kanaji, S S Nakade, T T Kanno, K K Mikoshiba
The effects of a novel membrane-penetrable modulator, 2APB (2-aminoethoxy diphenyl borate), on Ins(1,4,5)P3-induced Ca2+ release were examined. 2APB inhibited Ins(1,4,5)P3-induced Ca2+ release from ra...Read More

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