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硫酸安普霉素

产品编号 A106707 | CAS号 65710-07-8 | Aladdin
Apramycin sulfate salt
95%
组合的产品项目
货号 规格 库存 价格 数量
A106707-1g 95% 上海(8)
北方(8)
 
A106707-5g 95% 上海(>10)
北方(6)
 
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属性

密度 1.3780
存贮条件 储存温度 2-8°C

描述

产品介绍 易溶于水,不溶于甲醇、氯仿、乙酸乙酯等有机溶剂,其水溶液抗生素活性稳定。
别名 硫酸安普霉素 ;硫酸阿布拉霉素,安普霉素硫酸盐,杀螺吗啉;Nebramycin II
应用 干扰细菌蛋白质的合成。具体是干扰原核生物核糖蛋白质的合成而抑制动物体内的有害细菌,通过抑制大肠杆菌的增殖,改善肠粘膜结构,促进机体与生长有关的内分泌活动(调节生长激素、膜岛素和T3水平)的协同作用而促进畜禽生长,提高饲料利用率。
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标识符号 GHS07 GHS07, GHS08 GHS08
信号词 Danger
风险声明 (欧洲) R35;R61;
安全声明(欧洲) 53,26,36/37/39,45
警示性声明 P201,P305+P351+P338,P308+P313
危害码(欧洲) T
危害声明 H315,H319,H360
个人防护设备 Eyeshields,Faceshields,full-face particle respirator type N100 (US),Gloves,respirator cartridge type N100 (US),type P1 (EN143) respirator filter,type P2 (EN 143) respirator cartridges,type P3 (EN 143) respirator cartridges
WGK德国 3
参考文献
Andrea T Fessler, Kristina Kadlec, Stefan Schwarz
A novel apramycin resistance gene, apmA, was detected on the ca.-40-kb resistance plasmid pAFS11 from bovine methicillin-resistant Staphylococcus aureus (MRSA) of sequence type 398 (ST398). The apmA g...Read More
Albert Tsai, Sotaro Uemura, Magnus Johansson, Elisabetta Viani Puglisi, R Andrew Marshall, Colin Echeverría Aitken, Jonas Korlach, M?ns Ehrenberg, Joseph D Puglisi
Inferring antibiotic mechanisms on translation through static structures has been challenging, as biological systems are highly dynamic. Dynamic single-molecule methods are also limited to few simulta...Read More
Kristina Kadlec, Andrea T Fe?ler, Natacha Couto, Constan?a F Pomba, Stefan Schwarz
The aims of this study were to identify small staphylococcal plasmids that carry either the trimethoprim resistance gene dfrK or the apramycin resistance gene apmA and analyse them for their structure...Read More
Tanja Matt, Chyan Leong Ng, Kathrin Lang, Su-Hua Sha, Rashid Akbergenov, Dmitri Shcherbakov, Martin Meyer, Stefan Duscha, Jing Xie, Srinivas R Dubbaka, Déborah Perez-Fernandez, Andrea Vasella, V Ramakrishnan, Jochen Schacht, Erik C B?ttger
Aminoglycosides are potent antibacterials, but therapy is compromised by substantial toxicity causing, in particular, irreversible hearing loss. Aminoglycoside ototoxicity occurs both in a sporadic do...Read More
W Hong, S Yan
To engineer Streptomyces tenebrarius for producing carbamoyl tobramycin as a main component.The aprH-M gene fragment (apramycin biosynthetic gene from GenBank) in S. tenebrarius Tt49 was knocked out b...Read More
Amanda M Fenner, Robert J Kerns
Synthesis of amphiphilic oligosaccharides is problematic because traditional methods for separating and purifying oligosaccharides, including sulfated oligosaccharides, are generally not applicable to...Read More
Suk-Kyung SK Lim, Hyang-Mi HM Nam, Aeran A Kim, Gum-Chan GC Jang, Hee-Soo HS Lee, Suk-Chan SC Jung
To investigate apramycin resistance in humans in Korea, a total of 138 human Escherichia coli strains confirmed as gentamicin-resistant were collected from Korean Culture Collection Antimicrobial-Resi...Read More
Maksym Myronovskyi, Elisabeth Welle, Viktor Fedorenko, Andriy Luzhetskyy
Here we describe a versatile and sensitive reporter system for actinomycetes that is based on gusA, which encodes the β-glucuronidase enzyme. A series of gusA-containing transcriptional and translati...Read More
Min-Jung MJ Choi, Suk-Kyung SK Lim, Hyang-Mi HM Nam, Ae-Ran AR Kim, Suk-Chan SC Jung, Mal-Nam MN Kim
A total of 1921 Escherichia coli isolated from healthy animals (501 from cattle, 832 from pigs, and 588 from chickens) and 237 isolates from diseased pigs were tested to determine the prevalence of ap...Read More
Duccio Balenci, Nicola D'Amelio, Elena Gaggelli, Nicola Gaggelli, Luciano Cellai, Elena Molteni, Gianni Valensin
We're sorry this abstract is currently not available....Read More
Paulo Martins da Costa, Anabela Belo, José Gon?alves, Fernando Bernardo
The present study investigates, under field conditions, the influence of antimicrobial administration on prevalence and patterns of antimicrobial resistance among Escherichia coli and Enterococcus spp...Read More
Xiu Ying Zhang, Liang Jun Ding, Ming Z Fan
The aminoglycoside apramycin has been used widely in animal production in China since 1999. This study was aimed to investigate the resistance pattern of apramycin-resistant Escherichia coli isolated ...Read More
D D Balenci, G G Bonechi, N N D'Amelio, E E Gaggelli, N N Gaggelli, E E Molteni, G G Valensin, W W Szczepanik, M M Dziuba, G G Swiecicki, M M Jezowska-Bojczuk
The interaction of apramycin with copper at different pH values was investigated by potentiometric titrations and EPR, UV-vis and CD spectroscopic techniques. The Cu(II)-apramycin complex prevailing a...Read More
Yonghai Y Li, Weiqing W He, Yucheng Y Wang, Yiguang Y Wang, Rongguang R Shao
Genetic manipulation of geldanamycin (GDM) producer Streptomyces species is a rational approach to understand biosynthesis processes and create new analogues. In this study, the carbamoyltransferase g...Read More
Marta M Fedoryshyn, Lutz L Petzke, Elisabeth E Welle, Andreas A Bechthold, Andriy A Luzhetskyy
We report here a system for the functional expression of the Flp recombinase in several actinomycetes: Streptomyces coelicolor, S. lividans, and Saccharotrix espanaensis. We have constructed a synthet...Read More
Serena Bernacchi, Séverine Freisz, Clarisse Maechling, Bernard Spiess, Roland Marquet, Philippe Dumas, Eric Ennifar
Owing to a striking, and most likely fortuitous, structural and sequence similarity with the bacterial 16 S ribosomal A site, the RNA kissing-loop complex formed by the HIV-1 genomic RNA dimerization ...Read More
Liying Zhang, Zongyi Wang, Biying Chang, Wengjun Yang
A high-performance liquid chromatographic method for determining apramycin in animal feeds was developed. Apramycin in feeds was extracted with 0.1 M HCl solution and cleaned up with an MCX solid-phas...Read More
Jiro J Kondo, Mariana M Hainrichson, Igor I Nudelman, Dalia D Shallom-Shezifi, Christopher M CM Barbieri, Daniel S DS Pilch, Eric E Westhof, Timor T Baasov
The lack of absolute prokaryotic selectivity of natural antibiotics is widespread and is a significant clinical problem. The use of this disadvantage of aminoglycoside antibiotics for the possible tre...Read More
G J GJ Gunn, M M Hall, E A EA Hunter, J C JC Low
A random survey of farms in the Highlands and Islands of Scotland provides estimated of the prevalence of calves, finishers and cows carrying ampicillin, apramycin and/or nalidixic acid resistant Esch...Read More
Jiro J Kondo, Boris B Fran?ois, Alexandre A Urzhumtsev, Eric E Westhof
Aminoglycosides are highly effective antibacterial drugs that decrease translation accuracy by binding to the aminoacyl-tRNA decoding site (A site) of 16S ribosomal RNA. On the other hand, they are hi...Read More
C M Yates, D J Shaw, A J Roe, M E J Woolhouse, S G B Amyes
The study of antibiotic resistance has in the past focused on organisms that are pathogenic to humans or animals. However, the development of resistance in commensal organisms is of concern because of...Read More
Mingxuan Xu, Yingmin Zhu, Yinming Zhu, Zhikun Jin, Huiyuan Wu, Xiangfeng Li, Yunliu Yang, Ruisheng Jiao, Weihong Jiang, Houming Wu, Wei Tian, Xiufeng Bai, Guoping Zhao
Apramycin is unique in the aminoglycoside family due to its octodiose moiety. However, either the biosynthesis process or the precursors involved are largely unknown. Addition of glycine, as well as s...Read More
Vibeke F Jensen, Lotte Jakobsen, Hanne-Dorthe Emborg, Anne Mette Seyfarth, Anette M Hammerum
Resistance towards the veterinary drug apramycin can be caused by the aac(3)-IV gene, which also confers resistance towards the important human antibiotic gentamicin. The objectives of this study were...Read More
T-W TW Hahn, J D JD Lohakare, S L SL Lee, W K WK Moon, B J BJ Chae
Two experiments were conducted to evaluate the efficacy of beta-glucan on growth performance, nutrient digestibility, and immunity in weanling pigs. In Exp. 1, 210 weanling pigs (6.38 +/- 0.92 kg of B...Read More