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腺苷-5'-二磷酸钠盐水合物

产品编号 A107042 | CAS号 16178-48-6 | 阿拉丁
Adenosine 5'-Diphosphate Disodium Salt Hydrate
>98.0%(N)
组合的产品项目
货号 规格 库存 价格 数量
A107042-1g >98.0%(N) 上海(8)
北方(预计3-5个工作日)
 
A107042-25g >98.0%(N) 上海(预计3-7周)
北方(预计3-7周)
 
A107042-5g >98.0%(N) 上海(3)
北方(预计3-5个工作日)
 
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属性

敏感性 易吸潮;对热敏感
旋光率 -31 ° (C=0.5, 0.5M Na2HPO4)
密度 1.3600
存贮条件 储存温度:-20°C

描述

别名 焦磷酸腺苷,ADP钠盐,5’-二磷酸腺苷二钠;ADP钠盐;二磷酸腺苷二钠盐;5'-ADP-Na2; ADP Na2; ADP disodium salt dihydrate Adenosine 5'-diphosphoric acid disodium salt dihydrate
应用 腺苷5'-二磷酸(ADP)是通过ATP合成酶转化成ATP,从而参与能量储存和核酸代谢的腺嘌呤核苷酸。 ADP通过与ADP受体P2Y1、P2Y12和P2X1相互作用影响血小板活化。当其由 ecto-ADP酶催化为腺苷,血小板活化被腺苷受体抑制。
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安全声明(欧洲) S24/25;
个人防护设备 Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter
WGK德国 3
参考文献
David Erlinge
The purine- and pyrimidine-sensitive P2Y receptors belong to the large group of G-protein-coupled receptors that are the target of approximately one-third of the pharmaceutical drugs used in the clini...Read More
David D Iyú, Jackie R JR Glenn, Ann E AE White, Sue C SC Fox, Stan S Heptinstall
To investigate whether adenosine diphosphate (ADP)-derived adenosine might inhibit platelet aggregation, especially in the presence of a P2Y?? antagonist, where the effects of ADP at the P2Y?? recepto...Read More
Sarah Jones, Richard J Evans, Martyn P Mahaut-Smith
ADP is considered a weak platelet agonist due to the limited aggregation responses it induces in vitro at physiological concentrations of extracellular Ca(2+) [(Ca(2+) )(o) ]. Lowering [Ca(2+) ](o) pa...Read More
Béatrice B Hechler, Christian C Gachet
Following vessel wall injury, platelets adhere to the exposed subendothelium, become activated and release mediators such as TXA(2) and nucleotides stored at very high concentration in the so-called d...Read More