产品编号 A107073 | CAS号 29883-15-6 | Aladdin
货号 规格 库存 价格 数量
A107073-20mg 分析标准品,>98% 上海(预计4-8周)


旋光率 -40 ° (C=2, H2O)
密度 1.5900
熔点 223-226°C


产品介绍 三水合物为斜方柱状结晶(水), lg溶于900ml乙醇及11ml沸乙醇, 易溶于沸水。UVλMeOHmax nm(ε): 268(179), 262(255), 257(256), 251198), 208(7210); IRνmax cmˉ1: 3330, 2860, 1640, 1590, 1490, 1450, 1270, 1160, 1060, 690[1]。 植物来源:蔷薇科植物桃Prunus persica (L.)Batsch种子,巴旦杏P.amygdalus Batsch
别名 扁桃苷 ;苦杏仁甙,苦杏仁苷;D-Mandelonitrile 6-O-β-D-glucosido-β-D-glucoside D-Mandelonitrile-β-gentiobioside Laetrile
应用 生氰的糖苷是苦杏仁和杏仁凹点的组成部分。没有科学证据证明扁桃苷是抗癌物。最近的研究:联上瘤单克隆抗体的β−葡糖苷(β−glucoside)在瘤细胞里释放出氰,显示出很明显的细胞毒性。
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标识符号 GHS07 GHS07
信号词 Warning
风险声明 (欧洲) R22;
安全声明(欧洲) S26;S36/37/39/;S45;
危害码(欧洲) Xn
危害声明 H302
个人防护设备 dust mask type N95 (US),Eyeshields,Faceshields,Gloves
RTECS OO8450000
WGK德国 3
Cui-Ping CP Zhang, Huo-Qing HQ Zheng, Fu-Liang FL Hu
Extraction and assay conditions for β-glucosidase from propolis were optimized. Highest enzyme activity was obtained in a citric acid-disodium hydrogen phosphate buffer at pH 6.0 with 2.5% insoluble ...Read More
Xiaoyun X Shu, Yuping Y Tang, Chenxue C Jiang, Erxing E Shang, Xinshen X Fan, Anwei A Ding
A high performance liquid chromatographic (HPLC) method with diode array detection (DAD) was established for simultaneous determination of seven main bioactive components in San-ao decoction and its s...Read More
G J GJ Strugala, A G AG Rauws, R R Elbers
The intestinal first pass metabolism of amygdalin has been investigated in rat small intestine in vitro. The results show that amygdalin is hydrolyzed to prunasin, essentially in the wall of the proxi...Read More
Y Y Turan
Since At2g25630 is an intronless gene with a premature stop codon, its cDNA encoding the predicted mature beta-glucosidase isoenzyme was synthesized from the previously isolated Arabidopsis thaliana g...Read More
Ha-Jeong HJ Kwon, Je-Hyun JH Lee, Seon-Pyo SP Hong
Armeniacae Semen contains not only amygdalin but also emulsin, which is an enzyme that hydrolyzes amygdalin. This hydrolysis reaction has been a major problem associated with the water extraction of A...Read More
Anne Vinther Morant, Nanna Bjarnholt, Mads Emil Kragh, Christian Hauge Kjaergaard, Kirsten J?rgensen, Suzanne Michelle Paquette, Markus Piotrowski, Anne Imberty, Carl Erik Olsen, Birger Lindberg M?ller, S?ren Bak
Lotus japonicus accumulates the hydroxynitrile glucosides lotaustralin, linamarin, and rhodiocyanosides A and D. Upon tissue disruption, the hydroxynitrile glucosides are bioactivated by hydrolysis by...Read More
De-Bin Yang, Yan Tong, Zhen-Shan Ma, Lin Wang, Mei-Hong Dong, Yan-Ling Li, Jin-Yu Wang
To establish an HPLC method for the determination of ephedrine hydrochloride, D-pseudo-ephedrine and amygdalin in Xiao'er Pingchuan Qutan granule.Pheny ether chromatographic column (4.6 mm x 250 ...Read More
Letril (amygdaline) is one of drugs of alternative therapy for cancer that is used over three decades and relates to cyanogenic glycosides received from kernels of various fruits (almonds, apricots, p...Read More
Yu Chen, Jinshu Ma, Fang Wang, Jie Hu, Ai Cui, Chengguo Wei, Qing Yang, Fan Li
Amygdalin, a naturally occurring substance, has been suggested to be efficacious as an anticancer substance. The effect of amygdalin on cervical cancer cells has never been studied. In this study, we ...Read More
Noor M Shaik, Anurag Misra, Somesh Singh, Amol B Fatangare, Suryanarayanarao Ramakumar, Shuban K Rawal, Bashir M Khan
Glycosyl hydrolase family 1 β-glucosidases are important enzymes that serve many diverse functions in plants including defense, whereby hydrolyzing the defensive compounds such as hydroxynitrile gluc...Read More
Hossein H Mirmiranpour, Shahnaz S Khaghani, Ali A Zandieh, O Omid OO Khalilzadeh, Siavash S Gerayesh-Nejad, Afsaneh A Morteza, Alireza A Esteghamati
Angiogenesis contributes to different physiological and pathological conditions. The aim of this study was to investigate for the first time the antiangiogenic effects of amygdalin on the cultured end...Read More
Raquel Sánchez-Pérez, Fara Sáez Belmonte, Jonas Borch, Federico Dicenta, Birger Lindberg M?ller, Kirsten J?rgensen
Amygdalin is a cyanogenic diglucoside and constitutes the bitter component in bitter almond (Prunus dulcis). Amygdalin concentration increases in the course of fruit formation. The monoglucoside pruna...Read More
Li L Liu, Jin-ao JA Duan, Yuping Y Tang, Jianming J Guo, Nianyun N Yang, Hongyue H Ma, Xuqin X Shi
Persicae Semen (Taoren) and Carthami Flos (Honghua) used in pair which is named as Taoren-Honghua (TH) herb pair has been used in traditional Chinese medicine (TCM) for promoting blood circulation to ...Read More
Deng D Jiagang, Chunyang C Li, Hailian H Wang, Erwei E Hao, Zhengcai Z Du, Chuanhong C Bao, Jianzhen J Lv, Yi Y Wang
Regulatory T cells (Tregs) play a critical role in the regulation of T cell-mediated immune responses in atherosclerosis, a chronic autoimmune-like disease. Therefore, in this study, we aimed to inves...Read More
Lishuang Yu, Hongzhi Ye, Lili Zheng, Lidian Chen, Kedan Chu, Xianxiang Liu, Xueqin Xu, Guonan Chen
A new method for separation and determination of amygdalin and its epimer (neoamygdalin) in the epimerization of amygdalin by MEEKC is proposed. For the chiral separation of amygdalin and neoamygdalin...Read More
Minfeng M Fang, Zhiling Z Fu, Qilin Q Wang, Shixiang S Wang, Chaoni C Xiao, Xiaohui X Zheng
To study the influence of processing on metabolism of the main component of bitter almond-amygdalin in rat....Read More
Geraldine A Wright, Julie A Mustard, Nicola K Simcock, Alexandra A R Ross-Taylor, Lewis D McNicholas, Alexandra Popescu, Frédéric Marion-Poll
Avoiding toxins in food is as important as obtaining nutrition. Conditioned food aversions have been studied in animals as diverse as nematodes and humans [1, 2], but the neural signaling mechanisms u...Read More
Soon-Mi SM Shim, Hoonjeong H Kwon
In the present study, degradation of amygdalin in the human digestive fluids and absorption of its metabolites by the human small intestine were evaluated by simulating a gastrointestinal digestion mo...Read More
C L Brady, T Goszczynska, S N Venter, I Cleenwerck, P De Vos, R D Gitaitis, T A Coutinho
Eight yellow-pigmented, Gram-negative, rod-shaped, oxidase-negative, motile, facultatively anaerobic bacteria were isolated from onion seed in South Africa and from an onion plant exhibiting centre ro...Read More
Hai-Ke HK Du, Fu-Cheng FC Song, Xin X Zhou, He H Li, Jian-Peng JP Zhang
To evaluate effect of amygdalin on expression of four biomarkers in the animal model of pulmonary fibrosis induced by bleomycin....Read More
George John, Balachandran Vijai Shankar, Swapnil R Jadhav, Praveen Kumar Vemula
Molecular gels, the macroscopic products of a nanoscale bottom-up strategy, have emerged as a promising functional soft material. The prospects of tailoring the architecture of gelator molecules have ...Read More
Alexander M Abdelnoor
It is hypothesized that psoriasis is an autoimmune disease. The most recent therapeutic approach that proved to be more effective than earlier methods of treatment is the use of mAb/fusion proteins. E...Read More
Stephen Abban, Leon Brimer, Warda S Abdelgadir, Mogens Jakobsen, Line Thorsen
Cyanogenic food crops abound in nature with important crops like cassava forming the staple food for over half a billion people. Detoxification by hydrolysis of cassava cyanogenic glycosides often inv...Read More
Kejin K Zhu, Xiaoping X Sun, Xiujuan X Chang, Jianping J Qin, Xinyong X Lv, Zhenzhong Z Wang, Wei W Xiao
To investigate pharmacokinetic parameters of peoniflorin, albiflorin and amygdaloside after administration of Guizhi Fuling capsule in beagle dogs....Read More
Ebenezer O Farombi, Olatunde Owoeye
Recently, considerable attention has been focused on dietary and medicinal phytochemicals that inhibit, reverse or retard diseases caused by oxidative and inflammatory processes. Vernonia amygdalina i...Read More
Véronique J VJ Barthet, Ray R Bacala
A reference method (higher accuracy) and a routine method (higher throughput) were developed for the extraction of cyanogenic glycosides from flaxseed. Conditions of (essentially) complete extraction ...Read More
Xue-mei Li, Yi-yang Hu, Xiao-hua Duan
To explore the method and significance for studying active anti-liver fibrosis ingredients consisted Chinese medicine compound prescription based on Chinese medicine theory.Optimized prescription was ...Read More
K N Syrigos, G Rowlinson-Busza, A A Epenetos
We describe a novel version of antibody-directed enzyme prodrug therapy (ADEPT), with the use of amygdalin as prodrug. Amygdalin is a naturally occurring cyanogenic glycoside, which can be cleaved by ...Read More
C G Moertel, T R Fleming, J Rubin, L K Kvols, G Sarna, R Koch, V E Currie, C W Young, S E Jones, J P Davignon
One hundred seventy-eight patients with cancer were treated with amygdalin (Laetrile) plus a "metabolic therapy" program consisting of diet, enzymes, and vitamins. The great majority of thes...Read More
M P Chitnis, M K Adwankar, A J Amonkar
The anti-tumor activity of amygdalin (NSC 251222), commercially known as Laetrile, was investigated using P388 lymphocytic leukaemia and P815 mast-cell leukaemia in BDF1 mice. Doses varying from 200 m...Read More