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GriC and GriD constitute a carboxylic acid reductase involved in grixazone biosynthesis in Streptomyces griseus.
In grixazone biosynthesis by Streptomyces griseus, a key intermediate 3-amino-4-hydroxybenzoic acid (3,4-AHBA) is converted to another key intermediate 3-amino-4-hydroxybenzaldehyde (3,4-AHBAL). Two g...Read More
Arylamine N-acetyltransferase responsible for acetylation of 2-aminophenols in Streptomyces griseus.
An arylamine N-acetyltransferase (NAT) responsible for the N acetylation of exogenous 3-amino-4-hydroxybenzoic acid in Streptomyces griseus was identified and characterized. This enzyme was distinct f...Read More
The shikimate pathway, including seven enzymatic steps for production of chorismate via shikimate from phosphoenolpyruvate and erythrose-4-phosphate, is common in various organisms for the biosynthesi...Read More
3D-QSAR and molecular docking studies of benzaldehyde thiosemicarbazone, benzaldehyde, benzoic acid, and their derivatives as phenoloxidase inhibitors
Inhibitions of three classes compounds against phenoloxidase were investigated, and 3D-QSAR was performed. The interactions between compounds N18 and phenoloxidase active site were also studied using ...Read More