|别名||5-氨基-4-酮基戊酸盐酸盐;ALA ;5-Amino-4-oxopentanoic acid hydrochloride; δ-Aminolevulinic acid hydrochloride;ALA|
|生化机理||5-Aminolevulinic acid (5-ALA) is an intermediate in heme biosynthesis and being studied as an inducing reagent for protoporphyrin IX (PPIX) dependent fluorescence diagnosis of metastatic lymph nodes. 5-ALA is used for photodynamic therapy of diseases such as Paget’s disease and HPV infection-associated cervical condylomata acuminata.|
Fluorescence diagnosis of metastatic lymph nodes using 5-aminolevulinic acid (5-ALA) in a mouse model of colon cancer.
Lymph node metastasis is one of the most critical prognostic factors in patients with colorectal cancer. Although regional lymph nodes should be surgically resected and pathologically examined, techni...Read More
[Three stages of 5-aminolevulinic acid-photodynamic therapy for condyloma acuminatum of external urethral meatus].
To observe the effect of the three stages of 5-aminolevulinic acid-photodynamic therapy (ALA-PDT) on condyloma acuminatum of external urethral meatus.A total of 56 patients with condyloma acuminatum o...Read More
Incomplete efficacy of 5-aminolevulinic acid (5 ALA) photodynamic therapy in the treatment of widespread extramammary Paget's disease.
Photodynamic therapy (PDT) using 5-aminolevulinic acid (5-ALA) is an effective treatment for several conditions such as Bowen's disease, subsets of basal cell carcinomas and actinic keratosis. Su...Read More
Differential response of porcine osteoblasts and chondrocytes in cell or tissue culture after 5-aminolevulinic acid-based photodynamic therapy
Objective: Outcome in osteochondral allografting is limited by the immunological incompatibility of the grafted tissue. Based on a resistance of chondrocytes to photodynamic therapy in cell culture it...Read More