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2-氨基-4-甲基吡啶

产品编号 A107213 | CAS号 695-34-1 | Aladdin
2-Amino-4-picoline
97%
组合的产品项目
货号 规格 库存 价格 数量
A107213-100g 97% 上海(>10)
北方(预计3-5个工作日)
 
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属性

密度 1.0680
熔点 96-101°C
沸点 230°C

描述

产品介绍 水中溶解度:41 g/L (20°C),溶于小分子醇,微溶于石油醚。
别名 2-氨基-4-甲基吡啶 ;2-氨基-4-皮考林;2-Amino-4-methylpyridine 4-Methylpyridin-2-amine
应用 医药中间体。
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标识符号 GHS06 GHS06, GHS08 GHS08
信号词 Danger
风险声明 (欧洲) R24/25;R36/37/38
安全声明(欧洲) S26;S36/37;S45
警示性声明 P261,P280,P301+P310,P311
危害码(欧洲) T
危害声明 H301,H311,H331,H373
个人防护设备 Eyeshields,Faceshields,Gloves,type P2 (EN 143) respirator cartridges
RTECS TJ5150000
WGK德国 3
Merck Index 466
闪点(摄氏) 118 °C
UN代码 2811
参考文献
We're sorry this abstract is currently not available....Read More
Ullvi Bluhm, Jean-Luc Boucher, Uwe Buss, Bernd Clement, Friederike Friedrich, Ulrich Girreser, Dieter Heber, Thanh Lam, Michel Lepoivre, Mojgan Rostaie-Gerylow
A series of new 3-aroylpyrido[1,2-a]pyrimidines were synthesized from aryl methyl ketones in a simple two-step procedure and evaluated as nitric oxide synthases (NOS) inhibitors. In order to perform a...Read More
I Bryndal, E Kucharska, W S?siadek, M Wandas, T Lis, J Lorenc, J Hanuza
The crystal structures of 2-amino-4-methyl-3-nitropyridine (I), 2-amino-4-methyl-3,5-dinitropyridine (II) and 2-amino-4-methyl-5-nitropyridine (III) have been determined. The compounds crystallize in ...Read More
Biswarup Saha, Md Maidul Islam, Susmita Paul, Saheli Samanta, Shayoni Ray, Chitta Ranjan Santra, Somnath Ray Choudhury, Biswajit Dey, Amrita Das, Somnath Ghosh, Subrata Mukhopadhyay, Gopinatha Suresh Kumar, Parimal Karmakar
The DNA binding property of a Cu(II) complex, viz., [Cu(mal)(2)](picH)(2).2H(2)O, (mal)(2) = malonic acid, picH = protonated 2-amino-4-picoline, has been investigated in this study. The binding of thi...Read More
Somnath Ray Choudhury, Biswajit Dey, Suranjana Das, Arturo Robertazzi, Atish Dipankar Jana, Chih-Yuan Chen, Hon Man Lee, Patrick Gamez, Subrata Mukhopadhyay
The crystal lattice of the three isostructural compounds , (C(6)H(8)N(2)H)(2)[M(C(3)H(2)O(4))(2)(H(2)O)(2)].4H(2)O (C(6)H(8)N(2)H = protonated 2-amino-4-picoline, M = Ni/Co/Mn, C(3)H(4)O(4) = malonate...Read More
Eun-Ae EA Jo, Ji-Hyun JH Lee, Chul-Ho CH Jun
The hydroacylation of methanol with alkenes was developed using a catalytic system consisting of Rh(I), 2-amino-4-picoline and benzoic acid; the reaction is speculated to occur by the initial N-methyl...Read More
Sheela Sharma, Betty P Wilkinson, Pu Gao, Vernon E Steele
A model to study the effectiveness of potential chemopreventive agents that inhibit neoplastic process by different mechanisms has been used to test the efficacy of seven nitric oxide synthase (NOS) i...Read More
R R Boer, W R WR Ulrich, T T Klein, B B Mirau, S S Haas, I I Baur
We have investigated various nitric oxide (NO) synthase inhibitors for their affinity and selectivity toward the three human isoenzymes in radioligand binding experiments. Therefore, we developed the ...Read More
W S WS Faraci, A A AA Nagel, K A KA Verdries, L A LA Vincent, H H Xu, L E LE Nichols, J M JM Labasi, E D ED Salter, E R ER Pettipher
1. The ability of 2-amino-4-methylpyridine to inhibit the catalytic activity of the inducible NO synthase (NOS II) enzyme was characterized in vitro and in vivo. 2. In vitro, 2-amino-4-methylpyridine ...Read More
W E WE Glover
The effect of 4-aminopyridine (4AP) and 4-methyl-2-aminopyridine (4M2AP), 10(-3) M, was studied on isolated spontaneously beating right atria and electrically driven left atria of the rabbit and the c...Read More
F F Bergmann, R R Elam
2-Amino-4-methylpyridine (2-AMP), when implanted into the ventral lateral thalamus of rats, does not cause stereotyped behavior. On the other hand, when compulsive biting and gnawing was evoked by tha...Read More
K K Simeonova, I I Lambev, I I Krushkov
We're sorry this abstract is currently not available....Read More
G G Anandha Babu, P P Ramasamy
2-Amino-4-picolinium toluene sulfonate (2A4PTS), a new organic material, was synthesized and grown as single crystals in room temperature by slow evaporation solution growth technique using water as s...Read More
Ravil R Petrov, Ruben S Vardanyan, Yeon S Lee, Shou-wu Ma, Peg Davis, Lucinda J Begay, Josephine Y Lai, Frank Porreca, Victor J Hruby
An enkephalin analogue coupled to 'aminofentanyl' has been synthesized and tested for biological activities at the mu and delta opioid receptors. Aminofentanyl which represents a structural ...Read More
Sherif Y SY Saad, Tawfeeg A O TA Najjar, Mohammed H MH Daba, Ammar C AC Al-Rikabi
Nitric oxide (NO) has been shown to play a role in maintaining normal renal function. However, the role of NO in cisplatin (CDDP)-induced nephrotoxicity is still unclear. The aim of the present work w...Read More
M W MW Fryer, W E WE Glover
1. The effects of 4-methyl-2-aminopyridine (4M2AP) and 4-aminopyridine (4AP) on spontaneous and evoked [3H]-noradrenaline overflow were compared in rabbit ear artery strips. The effects of 4M2AP on sm...Read More
E R Pettipher, T A Hibbs, M A Smith, R J Griffiths
We're sorry this abstract is currently not available....Read More
I I Panova, I I Kurshkov, P P Uzunov
The authors examined the effect of the new Bulgarian antihypotensive prepavation aminton (2-amino-4-methyl pyridine) on the noradrenaline and adrenaline depots in the heart of rats. They found that am...Read More
N Kiloh, A L Harvey, W E Glover
4-Methyl-2-aminopyridine (4M2AP) increased responses of isolated rat diaphragm and chick biventer cervicis nerve-muscle preparations to nerve stimulation but depressed responses to direct stimulation....Read More
M M Vlaskovska, I I Krushkov
The effect of the combined preparation analgeton and its components--analgin (metamizol, noramidopyrindimethansulfonate) and aminton (2-amino-4-methyl-pyridinphosphate) was studied on the release of b...Read More
Elsa D Garcin, Andrew S Arvai, Robin J Rosenfeld, Matt D Kroeger, Brian R Crane, Gunilla Andersson, Glen Andrews, Peter J Hamley, Philip R Mallinder, David J Nicholls, Stephen A St-Gallay, Alan C Tinker, Nigel P Gensmantel, Antonio Mete, David R Cheshire,
Nitric oxide synthase (NOS) enzymes synthesize nitric oxide, a signal for vasodilatation and neurotransmission at low concentrations and a defensive cytotoxin at higher concentrations. The high active...Read More