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血管紧张素II

¥ 431.10

产品编号 A107852 | CAS号 4474-91-3 | Aladdin
Angiotensin Ⅱ, human
90%
  • 分子式 C50H71N13O12
  • 分子量1046.18
  • Beilstein号
  • EC号
  • MDL号
  • PubChem编号 24891466
组合的产品项目
货号 规格 库存 价格 数量
A107852-10mg 90% 上海(>10)
北方(预计3-5个工作日)
 
A107852-25mg 90% 上海(5)
北方(预计3-5个工作日)
 
A107852-5mg 90% 上海(>10)
北方(预计3-5个工作日)
 
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属性

敏感性 热敏感
密度 1.4300
溶解性 Soluble in Water (25 mg/ml), and 5% Acetic Acid (1 mg/ml).
存贮条件 -20℃保存

描述

产品介绍 Angiotensin II plays an important role in the regulation of blood pressure and has strong vasoconstrictive effects. It also stimulates the release of aldosterone from the adrenal gland and inhibits adenylate cyclase activity in spontaneously hypertensive rats. Angiotensin II increases the entry of Ca2+ in heart muscle via voltage-sensitive channels and activates myosin light chain kinase (MYLK). It also elicits an increase in voltage-dependent delayed rectifier K+ current in neurons and activates JAK2 in smooth muscle cells. Furthermore, angiotensin II activates FAK (p125FAK) and a cytosolic 115-120 kDa calcium-dependent tyrosine kinase in rat epithelial cells. It also activates c-Src (p60c-src), ERK1/2, JNK, and p38α (p38 MAP Kinase) in vascular smooth muscle cells. The amino acid sequence Asp-Arg-Val-Tyr-Ile-His-Pro-Phe
别名 ;Hypertensin II; Ang II;
应用 A peptide involved in the regulation of blood pressure
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