|别名||蒽酮 ;9,10-二氢-9-氧蒽;9,10-Dihydro-9-oxoanthracene Carbothrone；Anthranone 9(10H)-Anthracenone 9-Oxodihydroanthracene|
|个人防护设备||dust mask type N95 (US),Eyeshields,Gloves|
Hypericins and thioredoxin reductase: Biochemical and docking studies disclose the molecular basis for effective inhibition by naphthodianthrones
Cytosolic (TrxR1) and mitochondrial (TrxR2) thioredoxin reductases experience pronounced concentration- and time-dependent inhibition when incubated with the two naphthodianthrones hypericin and pseud...Read More
Plants that contain anthracene-derived compounds such as anthraquinones have been reported to act as anticancer besides their use for millennia to treat constipation, but the mechanism of action is st...Read More
A chemical screening approach reveals that indole fluorescence is quenched by pre-fibrillar but not fibrillar amyloid-beta.
Aggregated amyloid-beta (Abeta) peptide is implicated in the pathology of Alzheimer's disease. In vitro and in vivo, these aggregates are found in a variety of morphologies, including globular ol...Read More
Production of ROS by photosensitized anthracene under sunlight and UV-R at ambient environmental intensities.
The aim of this study was to analyze the photostability and phototoxicity mechanism of anthracene (ANT) in a human skin epidermal cell line (HaCaT) at ambient environmental intensities of sunlight/UV-...Read More
In vitro antimicrobial and antioxidant activities of anthrone and chromone from the latex of Aloe harlana Reynolds.
In the search for new antimicrobial and antioxidant compounds from plants, the latex of the medicinal plant Aloe harlana Reynolds from Ethiopia was subjected to bioassay-guided fractionation, which le...Read More
Catalyzed by the bifunctional tertiary amino-thiourea organocatalyst derived from epicinchona alkaloid, the asymmetric Michael addition of anthrone to enone was achieved in high yield with excellent e...Read More
On the basis of gene disruption and enzyme activity, hypC, an open reading frame in the region between the pksA (aflC) and nor-1 (aflD) genes in the aflatoxin biosynthesis gene cluster, encodes a 17-k...Read More
Polyketides are a class of natural products with diverse structures and biological activities. The structural variability of aromatic products of fungal nonreducing, multidomain iterative polyketide s...Read More
Photooxidation of a platinum-anthracene pincer complex: formation and structures of Pt(II)-anthrone and -ketal complexes.
Irradiating the cyclometalated pincer complex Pt(II)(DPA)Cl (1, DPA = 1,8-bis(diphenylphosphino)anthracene) in the presence of O(2) led to three sequential oxidations of the anthracenyl ring. The firs...Read More
Inulin clearance (Cin) is widely considered to be a gold-standard assessment of glomerular filtration rate (GFR). Although inulin concentrations are commonly determined by the anthrone method, this me...Read More
It is important for gene carrier to transport DNA into target cells. Although viral vectors are very efficient gene-transfer vehicles, significant drawbacks limit their applications. Chitosan (CS) has...Read More
Soil-applied imidacloprid is translocated to nectar and kills nectar-feeding Anagyrus pseudococci (Girault) (Hymenoptera: Encyrtidae).
Behavior was altered and survivorship was reduced when parasitoids, Anagyrus pseudococci (Girault) (Hymenoptera: Encyrtidae), were fed flowers from buckwheat, Fagopyrum esculentum L. (Polygonaceae), t...Read More
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Rapid and sensitive anthrone-sulfuric acid assay in microplate format to quantify carbohydrate in biopharmaceutical products: Method development and validation
The need for an accurate, fast and reliable analysis of carbohydrate test is crucial for numerous biological processes. In that sense, anthrone-sulfuric acid assay is one of the most efficient quantif...Read More
An organic luminescence material of white light was investigated. The organic luminescence film was made by heating and melting method. The film consists of riboflavin, anthrone derivative, and linear...Read More
According to Forster's theory about energy transfer, the energy transfer between riboflavin and anthrone derivative was investigated. It was found that there is a notable energy transfer between ...Read More
In a study of the anthraderivatives in roots of Rheum emodi, three new anthrone C-glucosides, named 10-hydroxycascaroside C (1), 10-hydroxycascaroside D (2) and 10R-chrysaloin 1-O-beta-D-glucopyranosi...Read More
Cytotoxicity-based, bioassay-guided fractionation of the chloroform-soluble extracts of both the roots and leaves of Picramnia latifolia led to the isolation of two new anthrone C-glycosides, picramni...Read More
A microtiter modification of the anthrone-sulfuric acid colorimetric assay for glucose-based carbohydrates
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Expression, purification, and characterization of AknX anthrone oxygenase, which is involved in aklavinone biosynthesis in Streptomyces galilaeus.
In streptomycete anthracycline biosynthetic gene clusters, small open reading frames are located just upstream of minimal polyketide synthase genes. aknX is such a gene found in the aklavinone-aclacin...Read More
From the aerial parts of Rubus ulmifolius Schott three new anthrones, rubanthrone A, B and C, have been isolated. Their structures were established by spectral procedures including 1D and 2D NMR techn...Read More
Four dianthrones, two oxymethylanthraquinones, two reductive forms of anthraquinones and five flavonoids have been isolated from the plant source Hypericum attenuatum Choisy (Guttiferae) firstly inves...Read More
Quantitative changes of dianthrones, hyperforin and flavonoids content in the flower ontogenesis of Hypericum perforatum.
Samples of Hyperici herba were obtained by harvesting Hypericum perforatum L. in different plant development stages. The relation of flower development phases in the drug's flower fraction was ex...Read More
Structural elucidation of homometallic anthracenolates synthesised via deprotonative metallation of anthrone.
Five novel neutral homometallic complexes which contain the anthracen-9-olate anion have been prepared and characterised by treating anthrone with an organometallic base to induce aromatisation. Three...Read More
Cytochrome P450 monooxygenases involved in anthracene metabolism by the white-rot basidiomycete Phanerochaete chrysosporium.
Cytochrome P450 monooxygenases (P450s) involved in anthracene metabolism by the white-rot basidiomycete Phanerochaete chrysosporium were identified by comprehensive screening of both catalytic potenti...Read More
Structure and kinetics of a transient antibody binding intermediate reveal a kinetic discrimination mechanism in antigen recognition.
Induced fit is a predominant phenomenon in protein-ligand interactions, yet it is invariably attributed without establishing the existence, let alone the structure, of the initial, low-affinity encoun...Read More
Effects of polyphenolic anthrone derivatives, resistomycin and hypercin, on apoptosis in human megakaryoblastic leukemia CMK-7 cell line.
A tetrahydroxyanthrone derivative, resistomycin, was isolated from the culture broth of Streptomyces sulphureus and a similar polyphenolic dianthraquinone, hypericin, was isolated from an extract of H...Read More