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腺嘌呤

¥ 86.00

产品编号 A108804 | CAS号 73-24-5 | Aladdin
Adenine
98%
组合的产品项目
货号 规格 库存 价格 数量
A108804-100g 98% 上海(7)
北方(9)
 
A108804-2.5kg 98% 上海(1)
北方(预计3-5个工作日)
 
A108804-25g 98% 上海(>10)
北方(预计3-5个工作日)
 
A108804-500g 98% 上海(预计3-7周)
北方(2)
 
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属性

敏感性 对湿度敏感
密度 1.6120
熔点 >360°C
溶解性 Soluble in water (0.5 g/L) at 20 °C, hot NH4OH, DMSO, alkali, acid, and hot water. Insoluble in chloroform, and ether.
存贮条件 室温保存

描述

产品介绍 Adenine, Cell Culture is synthetic and therefore free of any contamination with related natural products.
别名 6-氨基嘌呤;维生素 B4;磷酸氨基嘌呤;6-Aminopurine;Vitamin B4
应用 A purine nucleobase and a component of DNA
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标识符号 GHS06 GHS06
信号词 Danger
风险声明 (欧洲) R22
安全声明(欧洲) S26;S36
警示性声明 P301+P310
危害码(欧洲) Xn
危害声明 H301
个人防护设备 dust mask type N95 (US),Eyeshields,Faceshields,Gloves
RTECS AU6125000
WGK德国 3
Merck Index 152
UN代码 2811
参考文献
Jennifer A Jacobsen, Jessica L Fullagar, Melissa T Miller, Seth M Cohen
Fragment-based lead design (FBLD) has been used to identify new metal-binding groups for metalloenzyme inhibitors. When screened at 1 mM, a chelator fragment library (CFL-1.1) of 96 compounds produced...Read More
Jung-Feng JF Hsieh, Shih-Hsiung SH Wu, Yu-Liang YL Yang, Kee-Fong KF Choong, Shui-Tein ST Chen
The 6-aminopurine and its analogues were evaluated as xanthine oxidase inhibitors. These inhibitors are likely to be adopted as candidates to treat gout....Read More
K Harada, S Shimoda, Y Sato, K Isse, H Ikeda, Y Nakanuma
An innate immune response to bacterial components is speculated to be involved in the pathogenesis of primary biliary cirrhosis (PBC). Recently, CD4-positive T helper type 17 (Th17) cells, characteriz...Read More
Rathore
Aloe vera L., a member of Liliaceae, is a medicinal plant and has a number of curative properties. We describe here the development of tissue culture method for high-frequency plantlet regeneration fr...Read More
S R Santosh Kumar, V Krishna, V Krishna, K Pradeepa, K Girish Kumar, A U Gnanesh
An in vitro regeneration protocol has been standardized via direct and indirect methods from excised root explants of C. bonduc, a threatened woody legume used for the treatment of contagious diseases...Read More
Naomi L NL Kruhlak, Sydney S SS Choi, Joseph F JF Contrera, James L JL Weaver, James M JM Willard, Kenneth L KL Hastings, Lawrence F LF Sancilio
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Paul P Bamborough, Murray J MJ Brown, John A JA Christopher, Chun-wa CW Chung, Geoff W GW Mellor
A kinase-focused screening set of fragments has been assembled and has proved successful for the discovery of ligand-efficient hits against many targets. Here we present some of our general conclusion...Read More
Denis Fourches, Julie C Barnes, Nicola C Day, Paul Bradley, Jane Z Reed, Alexander Tropsha
Drug-induced liver injury is one of the main causes of drug attrition. The ability to predict the liver effects of drug candidates from their chemical structures is critical to help guide experimental...Read More
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Next-generation sequencing technologies are revolutionizing genomics research. It is now possible to generate gigabase pairs of DNA sequence within a week without time-consuming cloning or massive inf...Read More
Jiyoung A Hong, Devayani P Bhave, Kate S Carroll
Mycobacterium tuberculosis adenosine-5'-phosphosulfate (APS) reductase is an iron-sulfur protein and a validated target to develop new antitubercular agents, particularly for the treatment of lat...Read More
Thomas T Borrmann, Aliaa A Abdelrahman, Rosaria R Volpini, Catia C Lambertucci, Edgars E Alksnis, Simone S Gorzalka, Melanie M Knospe, Anke C AC Schiedel, Gloria G Cristalli, Christa E CE Müller
Adenine derivatives bearing substituents in the 2-, N(6)-, 7-, 8-, and/or 9-position and a series of deazapurines were synthesized and investigated in [(3)H]adenine binding studies at the adenine rece...Read More
Hilary Phenix, Katy Morin, Cory Batenchuk, Jacob Parker, Vida Abedi, Liu Yang, Lioudmila Tepliakova, Theodore J Perkins, Mads K?rn
Inferring regulatory and metabolic network models from quantitative genetic interaction data remains a major challenge in systems biology. Here, we present a novel quantitative model for interpreting ...Read More
Alexander C Roy, Faylene A Lunn, Stephen L Bearne
CTP synthase (CTPS) catalyzes the conversion of UTP to CTP and is a recognized target for the development of anticancer, antiviral, and antiprotozoal agents. Xanthine and related compounds inhibit CTP...Read More
Christian R Frey, Graciela Andrei, Ivan Votruba, Carina Cannizzaro, Bin Han, Wanchi Fung, Magdeleine Hung, Xiaohong Liu, Romas Geleziunas, Pierre Fiten, Ghislain Opdenakker, Robert Snoeck, Tomas Cihlar
Background/Aim: GS 9219 is a double prodrug of antiproliferative nucleotide analog 9-(2-Phosphonylmethoxyethyl)guanine (PMEG), with potent in vivo efficacy against various hematological malignancies. ...Read More
Alyse M DeHaan, Natalie M Wolters, Evan T Keller, Kathleen M Woods Ignatoski
Bone metastasis occurs frequently in advanced prostate cancer (PCa) patients; however, it is not known why this happens. The epidermal growth factor receptor (EGFR) ligand EGF is available to early st...Read More
Michele W Tang, Soo-Yon Rhee, Silvia Bertagnolio, Nathan Ford, Susan Holmes, Kim C Sigaloff, Raph L Hamers, Tobias F Rinke de Wit, Herve J Fleury, Phyllis J Kanki, Kiat Ruxrungtham, Claudia A Hawkins, Carole L Wallis, Wendy Stevens, Gert U van Zyl, Weeraw
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To evaluate all renal functions in patients receiving TDF and other nucleoside analogues.A prospective controlled study evaluating glomerular and tubular functions was conducted in patients receiving ...Read More
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Riboswitches are mRNA-based molecules capable of controlling the expression of genes. They undergo conformational changes upon ligand binding, and as a result, they inhibit or promote the expression o...Read More
Santosh Kumar SK Rai, Meena M Sharma, Madhu M Jain, Abhishek A Awasthi, Dharmendra Kumar DK Purshottam, Narayanan Kuttanpillai NK Nair, Ashok Kumar AK Sharma
An efficient in vitro process for rapid production of cloned plants of Uraria picta has been developed employing nodal stem segments taken from field-grown plants. Explants showed bud-break followed b...Read More
Sanghamitra Samantaray, Satyabrata Maiti
Chlorophytum arundinaceum is an important medicinal plant and its tuberous roots are used for various health ailment treatments. It has become an endangered species in the Eastern Ghats, and a rare me...Read More
J C Wang, L L He, Q Chen
Either combination treatment or monotherapy using agents with a high genetic barrier are recommended for the retreatment of chronic hepatitis B (CHB) patients. In search of reasonable treatment, we co...Read More
James Fung, See-Ching Chan, Cindy Cheung, Man-Fung Yuen, Kenneth Siu-Ho Chok, William Sharr, Albert Chi-Yan Chan, Tan-To Cheung, Wai-Kay Seto, Sheung-Tat Fan, Ching-Lung Lai, Chung-Mau Lo
The long-term outcomes of oral antiviral therapy without hepatitis B immune globulin (HBIG) in prevention of reinfection with hepatitis B after liver transplantation are not known. We aimed to determi...Read More
Norah Terrault
Improvements in the outcomes of patients transplanted for hepatitis B virus (HBV) have been substantial in the past two decades. With current therapies, the vast majority of transplant recipients are ...Read More
Moriya Iwaizumi, Stephanie Tseng-Rogenski, John M Carethers
Human DNA mismatch repair (MMR) recognizes and binds 5-fluorouracil (5FU) incorporated into DNA and triggers a MMR-dependent cell death. Absence of MMR in a patient's colorectal tumor abrogates 5...Read More
Meltem Weger, Benjamin D Weger, Nicolas Diotel, Sepand Rastegar, Tsuyoshi Hirota, Steve A Kay, Uwe Str?hle, Thomas Dickmeis
The circadian clock co-ordinates physiology and behavior with the day/night cycle. It consists of a transcriptional-translational feedback loop that generates self-sustained oscillations in transcript...Read More
M R Nelson, R A Elion, C J Cohen, A Mills, S L Hodder, S Segal-Maurer, M Bloch, W Garner, B Guyer, S Williams, S Chuck, S Vanveggel, H Deckx, M Stevens
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Jared M Baeten, Jessica E Haberer, Albert Y Liu, Nirupama Sista
: Preexposure prophylaxis (PrEP), in which HIV-uninfected persons with ongoing HIV risk use antiretroviral medications to reduce their risk of acquiring HIV infection, is an efficacious and promising ...Read More
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Deborah Donnell, James P Hughes, Lei Wang, Ying Q Chen, Thomas R Fleming
: The development of interventions for systemic pre-exposure prophylaxis (PrEP) faces several significant challenges following the US Food and Drug Administration's approval of emtricitabine/teno...Read More
On June 12, 2013, the Thailand Ministry of Health and CDC published results from a randomized controlled trial of a daily oral dose of 300 mg of tenofovir disoproxil fumarate (TDF) that showed efficac...Read More
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Antiretroviral pre-exposure prophylaxis reduces sexual transmission of HIV. We assessed whether daily oral use of tenofovir disoproxil fumarate (tenofovir), an antiretroviral, can reduce HIV transmiss...Read More
Quarraisha Abdool Karim, Cheryl Baxter, Salim Abdool Karim
Topical microbicides are an important, promising but complex HIV prevention technology under development. After 11 disappointing effectiveness trial outcomes of 6 candidate products (some tested as mu...Read More
Yu-Chun Li
One advanced schistosomiasis patient with hepatitis B cirrhosis was treated with lamivudine and adefovir dipivoxil and the curative effect was satisfied....Read More
Ravindra K Gupta, Mark A Wainberg, Francoise Brun-Vezinet, Jose M Gatell, Jan Albert, Anders S?nnerborg, Jean B Nachega
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Mian-Er Cong, James Mitchell, Elizabeth Sweeney, Shanon Bachman, Debra L Hanson, Walid Heneine, J Gerardo García-Lerma
Daily preexposure prophylaxis (PrEP) with emtricitabine/tenofovir disoproxil fumarate (FTC/TDF) is a novel strategy for preventing human immunodeficiency virus infection. We investigated in macaques w...Read More
Jie Wang, Jun-Ping Shi, Jing Wu, Xiao-Xiao Huang, Meng-Fei Zhu, Guo-Qiang Lou
To understand the genotype characteristics and its evolution of patients with poor response to initial combined treatment of Lamivudine and Adefovir dipivoxil for chronic hepatitis B.We detected the H...Read More
Jonathan D Fuchs, Magdalena E Sobieszczyk, Tamra Madenwald, Doug Grove, Shelly T Karuna, Michele Andrasik, Adam Sherwat, Gail Broder, Kenneth Mayer, Beryl Koblin, Scott Hammer, Scott Hammer
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Since the introduction of new and efficient antiretroviraL treatment (ART), mortality and morbidity due to HIV infections have been greatly reduced. However, there is a growing incidence of chronic di...Read More
We're sorry this abstract is currently not available....Read More
K J Cortez, M A Proschan, L Barrett, D G Brust, Barry Weatherley, E Formentini, R T Davey, H Masur, M A Polis, A U Neumann And, S Kottilil
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Peter J Ruane, Edwin Dejesus, Daniel Berger, Martin Markowitz, U Fritz Bredeek, Christian Callebaut, Lijie Zhong, Srini Ramanathan, Martin S Rhee, Marshall W Fordyce, Kitty Yale
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Eleftherios Michailidis, Emily M Ryan, Atsuko Hachiya, Karen A Kirby, Bruno Marchand, Maxwell D Leslie, Andrew D Huber, Yee T Ong, Jacob C Jackson, Kamalendra Singh, Eiichi N Kodama, Hiroaki Mitsuya, Michael A Parniak, Stefan G Sarafianos
The K65R substitution in human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) is the major resistance mutation selected in patients treated with first-line antiretroviral tenofovir d...Read More
Jennifer M Belavic
We're sorry this abstract is currently not available....Read More
Stefan A SA Laufer, David M DM Domeyer, Thomas R F TR Scior, Wolfgang W Albrecht, Dominik R J DR Hauser
On the basis of ATP adenine, a series of adenine and purine derivatives was prepared and tested for their ability to inhibit a spectrum of disease-related kinases. There has been scant research invest...Read More
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