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阿脲 一水合物

产品编号 A109024 | CAS号 2244-11-3 | 阿拉丁
Alloxan monohydrate
98%
  • 分子式 C4H2N2O4 · H2O
  • 分子量160.08
  • Beilstein号 4573597
  • MDL号 MFCD00149399
  • PubChem编号 24891204
组合的产品项目
货号 规格 库存 价格 数量
A109024-25g 98% 上海(预计3-7周)
北方(预计3-7周)
 
A109024-5g 98% 上海(预计3-7周)
北方(1)
 
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属性

敏感性 对热、空气敏感
密度 1.6810
熔点 240°C
溶解性 Soluble in water (50 g/L), ethanol, acetone, glacial acetic acid, methanol, and Slightly soluble in chloroform, petroleum ether, toluene, ethyl acetate and acetic anhydride. Insoluble in ether.
存贮条件 储存温度2-8℃,充氩保存

描述

别名 四氧嘧啶一水合物;丙酮二酰脲;1,3-二氮六环四酮;2,4,5,6(1H,3H)-嘧啶四酮;2,4,5,6-四氧嘧啶;5,6-二氧尿嘧啶;2,4,5,6(1H,3H)-Pyrimidinetetrone; 2,4,5,6-Tetraoxypyrimidine; 5,6-Dioxyuracil; 2,4,5,6(1H,3H)-Pyrimidinetetrone monohydrate 2,4,5,6(1H,3H)-Pyrimidinetetrone monohydrate
生化机理 Alloxan monohydrate is a hydrated form of Alloxan, which has been shown to destroy β cells. Alloxan is also used in research models to induce diabetes.
应用 A cytotoxic compound that causes oxidative base damage to nuclear DNA.
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标识符号 GHS07 GHS07
信号词 Warning
风险声明 (欧洲) 20/21/22
安全声明(欧洲) 36
警示性声明 P280
危害码(欧洲) Xn
危害声明 H302,H312,H332
个人防护设备 dust mask type N95 (US),Eyeshields,Gloves
RTECS UW0492000
WGK德国 3
Merck Index 282
参考文献
S Ekins, A J Williams, J J Xu
Drug-induced liver injury (DILI) is one of the most important reasons for drug development failure at both preapproval and postapproval stages. There has been increased interest in developing predicti...Read More
Nigel N Greene, Lilia L Fisk, Russell T RT Naven, Reine R RR Note, Mukesh L ML Patel, Dennis J DJ Pelletier
Drug-induced liver injury is a major issue of concern and has led to the withdrawal of a significant number of marketed drugs. An understanding of structure-activity relationships (SARs) of chemicals ...Read More
Leandro P Moura, Guilherme M Puga, Wladimir R Beck, Inaian P Teixeira, Ana Carolina Ghezzi, Gláucio A Silva, Maria Alice R Mello
Diabetes mellitus is associated with metabolic dysfunctions, including alterations in circulating lipid levels and fat tissue accumulation, which causes, among other pathologies, non-alcoholic fatty l...Read More
Zhichao Liu, Qiang Shi, Don Ding, Reagan Kelly, Hong Fang, Weida Tong
Drug-induced liver injury (DILI) is a significant concern in drug development due to the poor concordance between preclinical and clinical findings of liver toxicity. We hypothesized that the DILI typ...Read More

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