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L-2-氨基丁酸

产品编号 A109788 | CAS号 1492-24-6 | 阿拉丁
L-2-Aminobutyric acid
99%
组合的产品项目
货号 规格 库存 价格 数量
A109788-100g 99% 上海(预计3-5个工作日)
北方(预计3-5个工作日)
 
A109788-1g 99% 上海(>10)
北方(>10)
 
A109788-25g 99% 上海(预计3-5个工作日)
北方(预计3-5个工作日)
 
A109788-500g 99% 上海(预计3-5个工作日)
北方(预计3-5个工作日)
 
A109788-5g 99% 上海(8)
北方(1)
 
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属性

密度 1.1050
熔点 300°C

描述

别名 L-(+)-2-氨基丁酸; L-α-氨基丁酸;(S)-2-氨基丁酸;(S)-(+)-2-氨基丁酸;(S)-(+)-2-氨基正丁酸;L-α-Aminobutyric acid;L(+)-2-Aminobutyric acid;(S)-(+)-2-Aminobutyric acid;2-Aminobutanoic acid;H-Abu-OH
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标识符号 GHS07 GHS07
信号词 Warning
风险声明 (欧洲) R43;
安全声明(欧洲) S36/37;
警示性声明 P280
危害码(欧洲) Xi
危害声明 H317
个人防护设备 dust mask type N95 (US),Eyeshields,Faceshields,Gloves
WGK德国 3
Merck Index 428
参考文献
Mark G MG Jones, Elizabeth E Cooper, Saira S Amjad, C Stewart CS Goodwin, Jeffrey L JL Barron, Ronald A RA Chalmers
Previous work by others have suggested the occurrence of one or more chemical or metabolic 'markers' for ME/CFS including specific amino acids and organic acids and a number of unidentified ...Read More
Marcus A Bain, Randall Faull, Robert W Milne, Allan M Evans
L-Carnitine has important roles in intermediary metabolism and patients with end-stage renal disease who are undergoing hemodialysis may develop a secondary L-carnitine deficiency. The extent of accum...Read More
E D ED Ehrenpreis, M M Salvino, R M RM Craig
D-Xylose absorption testing is a simple, low-cost method of screening for small intestinal malabsorption. The optimum method to measure D-xylose absorption (serum vs. urine testing) is uncertain....Read More
Marcus A Bain, Randall Faull, Gianfranco Fornasini, Robert W Milne, Allan M Evans
Trimethylamine (TMA) is a short-chain tertiary aliphatic amine that is derived from the diet either directly from the consumption of foods high in TMA or by the intake of food high in precursors to TM...Read More
H F HF Galley, A E AE Le Cras, K K Yassen, I S IS Grant, N R NR Webster
Nitric oxide synthase requires tetrahydrobiopterin for its activity. In animal models of sepsis, changes in circulating tetrahydrobiopterin concentrations precede increases in nitrate. We measured pla...Read More
Christian Fleck, Frank Schweitzer, Elke Karge, Martin Busch, Günter Stein
NO synthesis is inhibited by the dimethylarginine (DMA) ADMA, which accumulates, similar to SDMA, in the plasma of patients suffering from chronic renal failure (CRF). ADMA and possibly SDMA contribut...Read More
Keitaro K Yokoyama, Masamich M Tajima, Hiraku H Yoshida, Masaaki M Nakayama, Goro G Tokutome, Hiroshi H Sakagami, Tatsuo T Hosoya
Pteridine metabolism is impaired in the uraemic state. This may affect cardiovascular function and contribute to malnutrition. We wished to clarify further the impact of impaired pteridine metabolism....Read More
J Jankowski, M van der Giet, V Jankowski, S Schmidt, M Hemeier, B Mahn, G Giebing, M Tolle, H Luftmann, H Schluter, W Zidek, M Tepel
NO prevents atherogenesis and inflammation in vessel walls by inhibition of cell proliferation and cytokine-induced endothelial expression of adhesion molecules and proinflammatory cytokines. Reduced ...Read More
R R Paniagua, R R Claure, D D Amato, E E Flores, A A Pérez, E E Exaire
Patients with chronic renal failure often have low plasma zinc (Zn) levels. Some factors that may account for abnormal Zn metabolism in these patients are low dietary Zn intake, a specific Zn transpor...Read More
T T Takagi, T G TG Chung, A A Saito
The levels of putrescine, cadaverine, spermidine and spermine in uremic plasma were determined with an automatic polyamine analyzer with a 7.5 X 0.2 cm I.D. cation-exchange column using a stepwise sod...Read More
Moritz Butscheid, Christian Sch?fer, Stefanie Brenner, Dominik Alscher, Thomas Mürdter, Toshimitsu Niwa, Matthias Frischmann, Monika Pischetsrieder, Ulrich Klotz
Advanced glycation end products (AGEs), e.g., carboxymethyllysine (CML) or imidazolone are involved in several age-related disorders. Concerning their accumulation, the importance of hepatic and renal...Read More
D S Gill, V A Fonseca, M A Barradas, R Balliod, J F Moorhead, P Dandona
Plasma histamine concentrations were measured using a commercially available monoclonal antibody radioimmunoassay in 38 patients with nephrotic syndrome, end stage renal failure, those receiving haemo...Read More
Peter P Stenvinkel, Ernesto E Rodríguez-Ayala, Ziad A ZA Massy, Abdul Rashid AR Qureshi, Peter P Barany, Bengt B Fellstr?m, Olof O Heimburger, Bengt B Lindholm, Anders A Alvestrand
Myeloperoxidase (MPO), which is secreted during activation of neutrophils, may serve as one mechanistic link among persistent inflammation, oxidative stress, and cardiovascular disease. This study rel...Read More
D O McGregor, W J Dellow, M Lever, P M George, R A Robson, S T Chambers
Hyperhomocysteinemia is a risk factor for atherosclerosis that is common in chronic renal failure (CRF), but its cause is unknown. Homocysteine metabolism is linked to betaine-homocysteine methyl tran...Read More
D S DS Raj, M M Ouwendyk, R R Francoeur, A A Pierratos
The purpose of this study was to examine the effect of nocturnal hemodialysis (NHD) on serum amino acid (AA) profile....Read More
R A RA Burke, J B JB Moberly, H H Patel, T R TR Shockley, L L Martis
The presence of mixed disaccharides (maltose and isomaltose) in plasma from uremic patients has been previously investigated using gel-permeation chromatography. However, this method is unable to sepa...Read More
Chih-Kuang CK Chuang, Shuan-Pei SP Lin, Han-Hsiang HH Chen, Yi-Chou YC Chen, Tuan-Jen TJ Wang, Wen-Hsiang WH Shieh, Chih-Jen CJ Wu
The high prevalence of protein-energy malnutrition is a critical issue for patients with end stage renal disease (ESRD) on hemodialysis (HD) or continuous ambulatory peritoneal dialysis (CAPD). Levels...Read More
Kevin Guo, Liang Li
We report a new quantitative metabolome profiling technique based on differential (12)C-/(13)C-isotope dansylation labeling of metabolites, fast liquid chromatography (LC) separation and electrospray ...Read More
Iris I Thondorf, Valerie V Voigt, Sarah S Sch?fer, Sabine S Gebauer, Katja K Zebisch, Linda L Laug, Matthias M Brandsch
The proton-coupled amino acid transporter hPAT1 has recently gained much interest due to its ability to transport small drugs thereby allowing their oral administration. A three-dimensional quantitati...Read More
I G Fotheringham, N Grinter, D P Pantaleone, R F Senkpeil, P P Taylor
L-2-Aminobutyric acid was synthesised in a transamination reaction from L-threonine and L-aspartic acid as substrates in a whole cell biotransformation using recombinant Escherichia coli K12. The cell...Read More
Cintyu Wong, Danica Galoni? Fujimori, Christopher T Walsh, Catherine L Drennan
CytC3, a member of the recently discovered class of nonheme Fe(II) and alpha-ketoglutarate (alphaKG)-dependent halogenases, catalyzes the double chlorination of L-2-aminobutyric acid (Aba) to produce ...Read More
Jong-Shik Shin, Byung-Gee Kim
Asymmetric synthesis of an unnatural amino acid was demonstrated by omega-transaminase from Vibrio fluvialis JS17. L-2-Aminobutyric acid was synthesized from 2-oxobutyric acid and benzylamine with an ...Read More
Carl Henrik G?rbitz
The crystal structure of L-2-aminobutyric acid, an L-alanine analogue with an ethyl rather than a methyl side chain, has proved elusive owing to problems growing diffraction quality crystals. Good dif...Read More
Ulrich Arnold, Bayard R Huck, Samuel H Gellman, Ronald T Raines
The introduction of non-natural modules could provide unprecedented control over folding/unfolding behavior, conformational stability, and biological function of proteins. Success requires the interro...Read More
Jose A JA Cuesta-Seijo, Jinhua J Zhang, Ulf U Diederichsen, George M GM Sheldrick
The crystal structure of the PNA (peptide nucleic acid) oligomer H-Lys-HalG-AlaG-HalC-AlaG-HalC-AlaC-Lys-NH(2) (PNA1, amino acids with D-configuration are underlined, Ala = alanyl, Hal = homoalanyl) h...Read More
Izumi Kawabata, Yutaro Kashiwagi, Kazuki Obashi, Masamichi Ohkura, Junichi Nakai, Anthony Wynshaw-Boris, Yuchio Yanagawa, Shigeo Okabe
Synaptic remodelling coordinated with dendritic growth is essential for proper development of neural connections. After establishment of synaptic contacts, synaptic junctions are thought to become sta...Read More
Young-Man YM Seo, Sam S Mathew, Han-Seop HS Bea, Yong-Ho YH Khang, Sang-Hyeup SH Lee, Byung-Gee BG Kim, Hyungdon H Yun
A deracemization method was developed to generate optically pure L-homoalanine from racemic homoalanine using D-amino acid oxidase and ω-transaminase. A whole cell reaction using a biphasic system co...Read More
Gon?alo J L Bernardes, Lars Linderoth, Katie J Doores, Omar Boutureira, Benjamin G Davis
We're sorry this abstract is currently not available....Read More
Juan J Torras, David D Zanuy, Marco M Crisma, Claudio C Toniolo, Oscar O Betran, Carlos C Alemán
The conformational tendencies of C(alpha,alpha)-diethylglycine (Deg)-based peptides have been studied in solution using all atom molecular dynamics simulations. Specifically, the conformational effect...Read More
A N Fonteh, R J Harrington, A Tsai, P Liao, M G Harrington
Our aim was to determine changes in free amino acid (FAA) and dipeptide (DP) concentrations in probable Alzheimer's disease (pAD) subjects compared with control (CT) subjects using liquid chromat...Read More
M A MA Lovell, W R WR Markesbery
Markers of oxidative stress are increased in cerebrospinal fluid (CSF) of patients with Alzheimer disease (AD), although none of those reported are appropriate diagnostic markers because of the overla...Read More
M L Selley, D R Close, S E Stern
There is evidence that increased blood concentrations of homocysteine may be a risk factor for Alzheimer's disease. (E)-4-hydroxy-2-nonenal (HNE) is a neurotoxic product of lipid peroxidation tha...Read More
J A JA Molina, F J FJ Jiménez-Jiménez, A A Hernánz, E E Fernández-Vivancos, S S Medina, F F de Bustos, C C Gómez-Escalonilla, Y Y Sayed
Thiamine is an essential cofactor for several important enzymes involved in brain oxidative metabolism, such as the alpha-ketoglutarate dehydrogenase complex (KGDHC), pyruvate-dehydrogenase complex (P...Read More
Takashi T Abe, Hideo H Tohgi, Chiaki C Isobe, Takahiko T Murata, Chigumi C Sato
To investigate the possible role of oxidative RNA damage in the pathogenesis of Alzheimer's disease (AD), the concentrations of the oxidative stress marker 8-hydroxyguanosine (8-OHG) were measure...Read More
K J B?r, S Franke, B Wenda, S Müller, R Kientsch-Engel, G Stein, H Sauer
Increasing evidence suggests an interaction of oxidative stress and the formation of advanced glycation end products (AGE) in the onset and progression of Alzheimer's disease. We studied levels o...Read More
Francesco F Gasparrini, Marco M Pierini, Claudio C Villani, Antonello A Filippi, Maurizio M Speranza
The structure, stability, and reactivity of proton-bound diastereomeric [M x H x A]+ complexes between some amino acid derivatives (A) and several chiral tetra-amide macrocycles (M) have been investig...Read More
Tatsuo T Yajima, Yukiyo Y Aizawa, Mai M Nishida, Yusuke Y Sakaguchi, Tadashi T Shiraiwa
An attempt was made to use a simple procedure to obtain (R)- and (S)-2-aminobutanoic acids [(R)- and (S)-1] which are non-proteinogenic alpha-amino acids and are useful as chiral reagents in asymmetri...Read More
Babu B Joseph, Pramod W PW Ramteke, Pa Ashok PA Kumar
Staphylococcus epidermidis isolated from spoiled frozen marine fish samples exhibited optimum lipase activity of 8.1 U within 72 h in batch fermentation. Inducible effect of different sugars, nitrogen...Read More
Cornelia Reimmann, Hiten M Patel, Christopher T Walsh, Dieter Haas
In Pseudomonas aeruginosa, the antibiotic dihydroaeruginoate (Dha) and the siderophore pyochelin are produced from salicylate and cysteine by a thiotemplate mechanism involving the peptide synthetases...Read More
B D BD Green, V A VA Gault, P R PR Flatt, P P Harriott, B B Greer, F P M FP O'Harte
The two major incretin hormones, glucagon-like peptide-1 (GLP-1), and glucose-dependent insulinotropic polypeptide (GIP), are currently being considered as prospective drug candidates for treatment of...Read More
Jong Jin JJ Lee, Dinesh D Shetty, Yun-Sang YS Lee, Sang Eun SE Kim, Young Joo YJ Kim, Mi Kyung MK Hong, Ji Yeon JY Son, Jae Min JM Jeong
We evaluated new (111)In-labeled amino acid derivatives, in which the amino acids are conjugated with1,4,7,10-tetra-azacyclododecane-1,4,7,10-tetraacetic acid (DOTA), 1,4,7,10-tetraazacyclododecane-1,...Read More
Li Zhu, Rongsheng Tao, Yi Wang, Yu Jiang, Xin Lin, Yunliu Yang, Huabao Zheng, Weihong Jiang, Sheng Yang
L-2-Aminobutyric acid can be synthesized in a transamination reaction from L-threonine and L-aspartic acid as substrates by the action of threonine deaminase and aromatic aminotransferase, but the by-...Read More
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