产品编号 A109788 | CAS号 1492-24-6 | 阿拉丁
L-2-Aminobutyric acid
货号 规格 库存 价格 数量
A109788-100g 99% 上海(预计3-5个工作日)
A109788-1g 99% 上海(>10)
A109788-25g 99% 上海(预计3-5个工作日)
A109788-500g 99% 上海(预计3-5个工作日)
A109788-5g 99% 上海(8)


密度 1.1050
熔点 300°C


别名 L-(+)-2-氨基丁酸; L-α-氨基丁酸;(S)-2-氨基丁酸;(S)-(+)-2-氨基丁酸;(S)-(+)-2-氨基正丁酸;L-α-Aminobutyric acid;L(+)-2-Aminobutyric acid;(S)-(+)-2-Aminobutyric acid;2-Aminobutanoic acid;H-Abu-OH
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标识符号 GHS07 GHS07
信号词 Warning
风险声明 (欧洲) R43;
安全声明(欧洲) S36/37;
警示性声明 P280
危害码(欧洲) Xi
危害声明 H317
个人防护设备 dust mask type N95 (US),Eyeshields,Faceshields,Gloves
WGK德国 3
Merck Index 428
Mark G MG Jones, Elizabeth E Cooper, Saira S Amjad, C Stewart CS Goodwin, Jeffrey L JL Barron, Ronald A RA Chalmers
Previous work by others have suggested the occurrence of one or more chemical or metabolic 'markers' for ME/CFS including specific amino acids and organic acids and a number of unidentified ...Read More
Marcus A Bain, Randall Faull, Robert W Milne, Allan M Evans
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E D ED Ehrenpreis, M M Salvino, R M RM Craig
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Marcus A Bain, Randall Faull, Gianfranco Fornasini, Robert W Milne, Allan M Evans
Trimethylamine (TMA) is a short-chain tertiary aliphatic amine that is derived from the diet either directly from the consumption of foods high in TMA or by the intake of food high in precursors to TM...Read More
H F HF Galley, A E AE Le Cras, K K Yassen, I S IS Grant, N R NR Webster
Nitric oxide synthase requires tetrahydrobiopterin for its activity. In animal models of sepsis, changes in circulating tetrahydrobiopterin concentrations precede increases in nitrate. We measured pla...Read More
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Keitaro K Yokoyama, Masamich M Tajima, Hiraku H Yoshida, Masaaki M Nakayama, Goro G Tokutome, Hiroshi H Sakagami, Tatsuo T Hosoya
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J Jankowski, M van der Giet, V Jankowski, S Schmidt, M Hemeier, B Mahn, G Giebing, M Tolle, H Luftmann, H Schluter, W Zidek, M Tepel
NO prevents atherogenesis and inflammation in vessel walls by inhibition of cell proliferation and cytokine-induced endothelial expression of adhesion molecules and proinflammatory cytokines. Reduced ...Read More
R R Paniagua, R R Claure, D D Amato, E E Flores, A A Pérez, E E Exaire
Patients with chronic renal failure often have low plasma zinc (Zn) levels. Some factors that may account for abnormal Zn metabolism in these patients are low dietary Zn intake, a specific Zn transpor...Read More
T T Takagi, T G TG Chung, A A Saito
The levels of putrescine, cadaverine, spermidine and spermine in uremic plasma were determined with an automatic polyamine analyzer with a 7.5 X 0.2 cm I.D. cation-exchange column using a stepwise sod...Read More
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D S Gill, V A Fonseca, M A Barradas, R Balliod, J F Moorhead, P Dandona
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Peter P Stenvinkel, Ernesto E Rodríguez-Ayala, Ziad A ZA Massy, Abdul Rashid AR Qureshi, Peter P Barany, Bengt B Fellstr?m, Olof O Heimburger, Bengt B Lindholm, Anders A Alvestrand
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D O McGregor, W J Dellow, M Lever, P M George, R A Robson, S T Chambers
Hyperhomocysteinemia is a risk factor for atherosclerosis that is common in chronic renal failure (CRF), but its cause is unknown. Homocysteine metabolism is linked to betaine-homocysteine methyl tran...Read More
D S DS Raj, M M Ouwendyk, R R Francoeur, A A Pierratos
The purpose of this study was to examine the effect of nocturnal hemodialysis (NHD) on serum amino acid (AA) profile....Read More
R A RA Burke, J B JB Moberly, H H Patel, T R TR Shockley, L L Martis
The presence of mixed disaccharides (maltose and isomaltose) in plasma from uremic patients has been previously investigated using gel-permeation chromatography. However, this method is unable to sepa...Read More
Chih-Kuang CK Chuang, Shuan-Pei SP Lin, Han-Hsiang HH Chen, Yi-Chou YC Chen, Tuan-Jen TJ Wang, Wen-Hsiang WH Shieh, Chih-Jen CJ Wu
The high prevalence of protein-energy malnutrition is a critical issue for patients with end stage renal disease (ESRD) on hemodialysis (HD) or continuous ambulatory peritoneal dialysis (CAPD). Levels...Read More
Kevin Guo, Liang Li
We report a new quantitative metabolome profiling technique based on differential (12)C-/(13)C-isotope dansylation labeling of metabolites, fast liquid chromatography (LC) separation and electrospray ...Read More
Iris I Thondorf, Valerie V Voigt, Sarah S Sch?fer, Sabine S Gebauer, Katja K Zebisch, Linda L Laug, Matthias M Brandsch
The proton-coupled amino acid transporter hPAT1 has recently gained much interest due to its ability to transport small drugs thereby allowing their oral administration. A three-dimensional quantitati...Read More
I G Fotheringham, N Grinter, D P Pantaleone, R F Senkpeil, P P Taylor
L-2-Aminobutyric acid was synthesised in a transamination reaction from L-threonine and L-aspartic acid as substrates in a whole cell biotransformation using recombinant Escherichia coli K12. The cell...Read More
Cintyu Wong, Danica Galoni? Fujimori, Christopher T Walsh, Catherine L Drennan
CytC3, a member of the recently discovered class of nonheme Fe(II) and alpha-ketoglutarate (alphaKG)-dependent halogenases, catalyzes the double chlorination of L-2-aminobutyric acid (Aba) to produce ...Read More
Jong-Shik Shin, Byung-Gee Kim
Asymmetric synthesis of an unnatural amino acid was demonstrated by omega-transaminase from Vibrio fluvialis JS17. L-2-Aminobutyric acid was synthesized from 2-oxobutyric acid and benzylamine with an ...Read More
Carl Henrik G?rbitz
The crystal structure of L-2-aminobutyric acid, an L-alanine analogue with an ethyl rather than a methyl side chain, has proved elusive owing to problems growing diffraction quality crystals. Good dif...Read More
Ulrich Arnold, Bayard R Huck, Samuel H Gellman, Ronald T Raines
The introduction of non-natural modules could provide unprecedented control over folding/unfolding behavior, conformational stability, and biological function of proteins. Success requires the interro...Read More
Jose A JA Cuesta-Seijo, Jinhua J Zhang, Ulf U Diederichsen, George M GM Sheldrick
The crystal structure of the PNA (peptide nucleic acid) oligomer H-Lys-HalG-AlaG-HalC-AlaG-HalC-AlaC-Lys-NH(2) (PNA1, amino acids with D-configuration are underlined, Ala = alanyl, Hal = homoalanyl) h...Read More
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Young-Man YM Seo, Sam S Mathew, Han-Seop HS Bea, Yong-Ho YH Khang, Sang-Hyeup SH Lee, Byung-Gee BG Kim, Hyungdon H Yun
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Gon?alo J L Bernardes, Lars Linderoth, Katie J Doores, Omar Boutureira, Benjamin G Davis
We're sorry this abstract is currently not available....Read More
Juan J Torras, David D Zanuy, Marco M Crisma, Claudio C Toniolo, Oscar O Betran, Carlos C Alemán
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A N Fonteh, R J Harrington, A Tsai, P Liao, M G Harrington
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M A MA Lovell, W R WR Markesbery
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M L Selley, D R Close, S E Stern
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Thiamine is an essential cofactor for several important enzymes involved in brain oxidative metabolism, such as the alpha-ketoglutarate dehydrogenase complex (KGDHC), pyruvate-dehydrogenase complex (P...Read More
Takashi T Abe, Hideo H Tohgi, Chiaki C Isobe, Takahiko T Murata, Chigumi C Sato
To investigate the possible role of oxidative RNA damage in the pathogenesis of Alzheimer's disease (AD), the concentrations of the oxidative stress marker 8-hydroxyguanosine (8-OHG) were measure...Read More
K J B?r, S Franke, B Wenda, S Müller, R Kientsch-Engel, G Stein, H Sauer
Increasing evidence suggests an interaction of oxidative stress and the formation of advanced glycation end products (AGE) in the onset and progression of Alzheimer's disease. We studied levels o...Read More
Francesco F Gasparrini, Marco M Pierini, Claudio C Villani, Antonello A Filippi, Maurizio M Speranza
The structure, stability, and reactivity of proton-bound diastereomeric [M x H x A]+ complexes between some amino acid derivatives (A) and several chiral tetra-amide macrocycles (M) have been investig...Read More
Tatsuo T Yajima, Yukiyo Y Aizawa, Mai M Nishida, Yusuke Y Sakaguchi, Tadashi T Shiraiwa
An attempt was made to use a simple procedure to obtain (R)- and (S)-2-aminobutanoic acids [(R)- and (S)-1] which are non-proteinogenic alpha-amino acids and are useful as chiral reagents in asymmetri...Read More
Babu B Joseph, Pramod W PW Ramteke, Pa Ashok PA Kumar
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B D BD Green, V A VA Gault, P R PR Flatt, P P Harriott, B B Greer, F P M FP O'Harte
The two major incretin hormones, glucagon-like peptide-1 (GLP-1), and glucose-dependent insulinotropic polypeptide (GIP), are currently being considered as prospective drug candidates for treatment of...Read More
Jong Jin JJ Lee, Dinesh D Shetty, Yun-Sang YS Lee, Sang Eun SE Kim, Young Joo YJ Kim, Mi Kyung MK Hong, Ji Yeon JY Son, Jae Min JM Jeong
We evaluated new (111)In-labeled amino acid derivatives, in which the amino acids are conjugated with1,4,7,10-tetra-azacyclododecane-1,4,7,10-tetraacetic acid (DOTA), 1,4,7,10-tetraazacyclododecane-1,...Read More
Li Zhu, Rongsheng Tao, Yi Wang, Yu Jiang, Xin Lin, Yunliu Yang, Huabao Zheng, Weihong Jiang, Sheng Yang
L-2-Aminobutyric acid can be synthesized in a transamination reaction from L-threonine and L-aspartic acid as substrates by the action of threonine deaminase and aromatic aminotransferase, but the by-...Read More
Valentina Medici, Janet M Peerson, Sally P Stabler, Samuel W French, Jesse F Gregory, Maria Catrina Virata, Antony Albanese, Christopher L Bowlus, Sridevi Devaraj, Edward A Panacek, Nazir Rahim, John R Richards, Lorenzo Rossaro, Charles H Halsted
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Danica P Galoni?, Eric W Barr, Christopher T Walsh, J Martin Bollinger, Carsten Krebs
Enzymatic incorporation of a halogen atom is a common feature in the biosyntheses of more than 4,500 natural products. Halogenation of unactivated carbon centers in the biosyntheses of several compoun...Read More
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Apart from their crucial role in metabolism, pyridoxal 5'-phosphate (PLP)-dependent aminotransferases (ATs) constitute a class of enzymes with increasing application in industrial biotechnology. ...Read More
Yasuto Tsuruta, Maya Matsumoto, Hirofumi Inoue, Sayaka Munemura, Shigeru Yamano, Haruo Iguchi
A simple and highly sensitive HPLC for the determination of N-ethylglycine in urine was developed. The labeling reaction of N-ethylglycine with 4-(5,6-dimethoxy-2-phthalimidinyl)-2-methoxyphenylsulfon...Read More
L L Hagenfeldt, L L Bjerkenstedt, G G Edman, G G Sedvall, F A FA Wiesel
Plasma and cerebrospinal fluid (CSF) concentrations of amino acids were measured in 65 healthy volunteers (50 men and 15 women). The CSF levels of the monoamine metabolites homovanillic acid (HVA), 3-...Read More
W W Yang, K S KS Roth
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S S Engelborghs, B B Marescau, P P PP De Deyn
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Z Z Tu, M W MW Anders
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Brian D BD Whitaker, James W JW Knight
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Beatrice B Bocca, Giovanni G Forte, Francesco F Petrucci, Anna A Pino, Francesca F Marchione, Giuseppe G Bomboi, Oreste O Senofonte, Franco F Giubilei, Alessandro A Alimonti
The haematic concentration of 26 metals and the oxidative damage in 60 patients (20 males and 40 females) affected by Alzheimer's disease and 44 healthy individuals (33 males and 11 females) were...Read More
M A MA Raskind, E R ER Peskind, C C Holmes, D S DS Goldstein
High cerebrospinal fluid (CSF) norepinephrine (NE) concentrations in aging and Alzheimer's disease (AD) could reflect decreased NE clearance from central nervous system (CNS) extracellular fluid ...Read More
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H U HU Shetty, H W HW Holloway, M B MB Schapiro
Previous studies suggest the presence of increased concentrations of cerebral myo-inositol in Alzheimer disease (AD). To characterize this abnormality further, we quantified myo-inositol and several o...Read More
M O MO Kristensen, N C NC Gulmann, J E JE Christensen, K K Ostergaard, K K Rasmussen
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Anna Walter, Ulrike Korth, Michael Hilgert, Joachim Hartmann, Oksana Weichel, Marion Hilgert, Klaus Fassbender, Andrea Schmitt, Jochen Klein
Experimental and clinical studies give evidence for breakdown of membrane phospholipids during neurodegeneration. In the present study, we measured the levels of glycerophosphocholine (GPCh), phosphoc...Read More
Luc A Cynober
The plasma concentration of an amino acid (AA) is the result of its rates of appearance (Ra) in and disappearance (Rd) from plasma. As for most nutrients, AA Ra and Rd are tightly regulated and at the...Read More
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24S-Hydroxycholesterol (24OHC) and 27-hydroxycholesterol (27OHC) are two structurally similar oxysterols of different origins--the former almost exclusively formed in the brain and the latter formed t...Read More
D D Stacchiola, L L Burkholder, T T Zheng, M M Weinert, W T WT Tysoe
The chemisorptive enantioselectivity of propylene oxide is examined on Pd(111) surfaces templated by chiral 2-methylbutanoate and 2-aminobutanoate species. It has been found previously that chiral pro...Read More