¥ 83.16

产品编号 A110206 | CAS号 63968-64-9 | 阿拉丁
货号 规格 库存 价格 数量
A110206-100g 98% 上海(2)
A110206-1g 98% 上海(>10)
A110206-25g 98% 上海(5)
A110206-5g 98% 上海(>10)


旋光率 75 ° (C=0.5, MeOH)
密度 1.2400
熔点 156-157°C


产品介绍 易溶于氯仿、丙酮、乙酸乙酯和苯,溶于甲醇,乙醇,不溶于水。
别名 青蒿素 ;Arteannuin Qinghaosu
应用 抗疟药。
只有注册的用户才可以写评论。请 登录 创建帐户
个人防护设备 Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter
RTECS KD4170000
WGK德国 2
Merck Index 817
P N Soh, B Witkowski, D Olagnier, M-L Nicolau, M-C Garcia-Alvarez, A Berry, F Benoit-Vical
Malaria is one of the most significant causes of infectious disease in the world. The search for new antimalarial chemotherapies has become increasingly urgent due to the parasites' resistance to...Read More
Lixiao Ni, Kumud Acharya, Gaoxiang Ren, Shiyin Li, Yiping Li, Yong Li
The objectives of this work were to prepare and characterize an anti-algal sustained-release granule, then study its mode of action on Microcystis aeruginosa. The anti-algal sustained-release granule ...Read More
Danny W Wilson, Christine Langer, Christopher D Goodman, Geoffrey I McFadden, James G Beeson
Most current antimalarials for treatment of clinical Plasmodium falciparum malaria fall into two broad drug families and target the food vacuole of the trophozoite stage. No antimalarials have been sh...Read More
Sasmita Kumari Das Sutar, Gunanidhi Dhangadamajhi, Shantanu Kumar Kar, Manoranjan Ranjit
In the absence of definite marker for artemisinin (ART) resistance, molecular monitoring of its partner drug sulfadoxine pyrimethamine (SP) in artemisinin based combination therapy (ACTs) together wit...Read More
Jian-Xu Li, Xin Fang, Qin Zhao, Ju-Xin Ruan, Chang-Qing Yang, Ling-Jian Wang, David J Miller, Juan A Faraldos, Rudolf K Allemann, Xiao-Ya Chen, Peng Zhang
Most TPSs (terpene synthases) contain plasticity residues that are responsible for diversified terpene products and functional evolution, which provide a potential for improving catalytic efficiency. ...Read More
Esra Küpeli Akkol, Gülcan Avci, Ismail Kü?ükkurt, Hikmet Kele?, U?ur Tamer, Sinan Ince, Erdem Yesilada
Ethnopharmacological relevance: Thymbra spicata is a member of the Lamiaceae family; leaves of this plant have recently gained much popularity as a remedy to combat hypercholesterolaemia. Aim of the s...Read More
Jürg J Utzinger, Shu-Hua SH Xiao, Marcel M Tanner, Jennifer J Keiser
Schistosomiasis is a significant health issue caused by a blood fluke that affects more than 200 million individuals worldwide, over half of whom suffer from disease-associated symptoms. In areas of h...Read More
Louis H Miller, Xinzhuan Su
This year's Lasker DeBakey Clinical Research Award goes to Youyou Tu for the discovery of artemisinin and its use in the treatment of malaria--a medical advance that has saved millions of lives a...Read More
Sayed H Seif el-Din, Amir M Al-Hroob, Fatma A Ebeid
Artemether (Art), a derivative of the antimalarial artemisinin, also exhibit antischistosomal properties. N-acetylcysteine (NAC) has a diversity of applications, largely because of the chemical proper...Read More
Jill M JM Squires, Jorge F S JF Ferreira, David S DS Lindsay, Anne M AM Zajac
Haemonchus contortus is a blood-sucking abomasal parasite of small ruminants that is responsible for major losses to producers worldwide. Resistance of this nematode to commercial anthelmintics has pr...Read More
Kate B Gardner, Ipsita Sinha, Leyla Y Bustamante, Nicholas Pj Day, Nicholas J White, Charles J Woodrow
It has been known for over a decade that Plasmodium falciparum proteins are enriched in non-globular domains of unknown function. The potential for these regions of protein sequence to undergo high le...Read More
Ildiko R Dunay, Wing Chi Chan, Richard K Haynes, L David Sibley
Immunocompromised patients are at risk of developing toxoplasmosis, and although chemotherapy is available, standard treatments are often complicated by severe side effects. Artemisinin is a new highl...Read More
A Taylor Bright, Elizabeth A Winzeler
We're sorry this abstract is currently not available....Read More
Daniel E Neafsey
Plasmodium falciparum in Southeast Asia are gradually becoming resistant to artemesinin, a standard first-line treatment for malaria. Whole-genome sequencing offers a chance to better understand and p...Read More
C J Paddon, P J Westfall, D J Pitera, K Benjamin, K Fisher, D McPhee, M D Leavell, A Tai, A Main, D Eng, D R Polichuk, K H Teoh, D W Reed, T Treynor, J Lenihan, M Fleck, S Bajad, G Dang, D Dengrove, D Diola, G Dorin, K W Ellens, S Fickes, J Galazzo, S P G
In 2010 there were more than 200?million cases of malaria, and at least 655,000 deaths. The World Health Organization has recommended artemisinin-based combination therapies (ACTs) for the treatment o...Read More
Laura M Alcantara, Junwon Kim, Carolina B Moraes, Caio H Franco, Kathrin D Franzoi, Sukjun Lee, Lucio H Freitas-Junior, Lawrence S Ayong
Members of the ATP-binding cassette (ABC)-type transporter superfamily have been implicated in multidrug resistance in malaria, and various mechanistic models have been postulated to explain their int...Read More
Silas P Cook
We're sorry this abstract is currently not available....Read More
Bryan T Mott, Abhai Tripathi, Maxime A Siegler, Cathy D Moore, David J Sullivan, Gary H Posner
Malaria continues to be a difficult disease to eradicate largely because of the widespread populations it affects and the resistance that malaria parasites have developed against once very potent ther...Read More
Gaurav Sharma, Kaushal Kumar, Abhay Sharma, Veena Agrawal
Using in vitro bioassays, we evaluated the crude methanol, ethanol, chloroform, and acetone leaf extracts of Artemisia annua as well as pure artemisinin against late 3rd and early 4th instars of Culex...Read More
Sylla Thiam, Jean-Louis Ndiaye, Ibrahima Diallo, Patrick Gatonga, Fatou Ba Fall, Ndella E Diallo, Babacar Faye, Mamadou L Diouf, Medoune Ndiop, Mame B Diouf, Oumar Gaye, Moussa Thior
The National Malaria Control Programme in Senegal, introduced since 2006, artemisinin-based combination therapy (ACT administration) for the treatment of uncomplicated malaria cases. In this framework...Read More
Oyindamola O Abiodun, Reto Brun, Sergio Wittlin
ABSTRACT:Semi-synthetic artemisinin derivatives are powerful peroxidic drugs in artemisinin-based combination therapy (ACT) recommended as first-line treatment of Plasmodium falciparum malaria in dise...Read More
Ryan J DeLuca, Jennifer L Edwards, Laura D Steffens, Brian W Michel, Xiaoxiao Qiao, Chunyin Zhu, Silas P Cook, Matthew S Sigman
The Pd-catalyzed TBHP-mediated Wacker-type oxidation of internal alkenes is reported. The reaction uses 2-(4,5-dihydro-2-oxazolyl)quinoline (Quinox) as ligand and TBHP(aq) as oxidant to deliver single...Read More
Sarah V Kedenge, Beth P Kangwana, Evelyn W Waweru, Andrew J Nyandigisi, Jayesh Pandit, Simon J Brooker, Robert W Snow, Catherine A Goodman
There is considerable interest in the potential of private sector subsidies to increase availability and affordability of artemisinin-based combination therapies (ACTs) for malaria treatment. A cluste...Read More
Mostafa A Elfawal, Melissa J Towler, Nicholas G Reich, Douglas Golenbock, Pamela J Weathers, Stephen M Rich
Drugs are primary weapons for reducing malaria in human populations. However emergence of resistant parasites has repeatedly curtailed the lifespan of each drug that is developed and deployed. Current...Read More
Chuan Fu, Jiying Yu, Jing Zou, Lin He, Yun Dong, Yuan Huang
To develop a method for determining artemisinin in rat plasma in vivo.HPLC-MS was adopted. Estazolam was selected as an internal standard (I.S.). The sample and I.S. were extracted using methyl tertbu...Read More
Joseph N Jarvis, Cordelia E M Coltart, Martin Pule, Peter L Chiodini, Tom Doherty
We're sorry this abstract is currently not available....Read More
Olivo Miotto, Jacob Almagro-Garcia, Magnus Manske, Bronwyn Macinnis, Susana Campino, Kirk A Rockett, Chanaki Amaratunga, Pharath Lim, Seila Suon, Sokunthea Sreng, Jennifer M Anderson, Socheat Duong, Chea Nguon, Char Meng Chuor, David Saunders, Youry Se, C
We describe an analysis of genome variation in 825 P. falciparum samples from Asia and Africa that identifies an unusual pattern of parasite population structure at the epicenter of artemisinin resist...Read More
Monika Chugh, Vidhya Sundararaman, Saravanan Kumar, Vanga S Reddy, Waseem A Siddiqui, Kenneth D Stuart, Pawan Malhotra
Malaria parasites use hemoglobin (Hb) as a major nutrient source in the intraerythrocytic stage, during which heme is converted to hemozoin (Hz). The formation of Hz is essential for parasite survival...Read More
Beth P Kangwana, Sarah V Kedenge, Abdisalan M Noor, Victor A Alegana, Andrew J Nyandigisi, Jayesh Pandit, Greg W Fegan, Jim E Todd, Robert W Snow, Catherine A Goodman
Many patients with suspected malaria in sub-Saharan Africa seek treatment from private providers, but this sector suffers from sub-standard medicine dispensing practices. To improve the quality of car...Read More
Sakineh Pirahmadi, Sedigheh Zakeri, Mandana Afsharpad, Navid Dinparast Djadid
The emergence and spread of Plasmodium falciparum resistant to the commonly used anti-malarial drugs is a major challenge in the control and elimination of malaria. The present study provides informat...Read More
Prasanna Jagannathan, Mary K Muhindo, Abel Kakuru, Emmanuel Arinaitwe, Bryan Greenhouse, Jordan Tappero, Philip J Rosenthal, Frank Kaharuza, Moses R Kamya, Grant Dorsey
The burden of malaria has decreased in parts of Africa following the scaling up of control interventions. However, similar data are limited from high transmission settings.A cohort of 100 children, ag...Read More
Yongmei Gong, Byron M Gallis, David R Goodlett, Yi Yang, Hailing Lu, Eric Lacoste, Henry Lai, Tomikazu Sasaki
Transferrin (Tf) conjugates of monomeric artemisinin (ART) and artemisinin dimer were synthesized. The two conjugates, ART-Tf and dimer-Tf, retained the original protein structure, and formed stable a...Read More