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N-乙酰-L-色氨酸

产品编号 A111003 | CAS号 1218-34-4 | 阿拉丁
N-Acetyl-L-tryptophan
98%
组合的产品项目
货号 规格 库存 价格 数量
A111003-100g 98% 上海(2)
北方(预计3-5个工作日)
 
A111003-10g 98% 上海(6)
北方(5)
 
A111003-25g 98% 上海(>10)
北方(预计3-5个工作日)
 
A111003-5g 98% 上海(预计3-7周)
北方(预计3-7周)
 
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属性

旋光率 26 ° (C=1, 1mol/L NaOH)
密度 1.3300
熔点 186°C
存贮条件 储存温度2-8°C

描述

别名 N-乙酰-L-色氨酸;
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个人防护设备 Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter
WGK德国 2
参考文献
Griet G Van Zeebroeck, Beatriz Monge BM Bonini, Matthias M Versele, Johan M JM Thevelein
Transporter-related nutrient sensors, called transceptors, mediate nutrient activation of signaling pathways through the plasma membrane. The mechanism of action of transporting and nontransporting tr...Read More
Christine M Barry, Stephen C Helps, Corinna van den Heuvel, Robert Vink
Background: Raised intracranial pressure (ICP) following SAH predicts poor outcome and is due to hemorrhage volume and possibly, brain edema, hydrocephalus and increased volume of circulating intracra...Read More
Renée J RJ Turner, Stephen C SC Helps, Emma E Thornton, Robert R Vink
Previous studies have suggested that substance P (SP) plays a critical role in the development of brain oedema and functional deficits following traumatic brain injury and that SP receptor antagonism ...Read More
James J JJ Donkin, Ibolja I Cernak, Peter C PC Blumbergs, Robert R Vink
Previous studies have demonstrated that the compound N-acetyl-L-tryptophan (NAT) reduces brain edema and improves functional outcome following traumatic brain injury (TBI). In this study we examined w...Read More
Kate M Lewis, Elizabeth Harford-Wright, Robert Vink, Mounir N Ghabriel
Emend, an NK1 antagonist, and dexamethasone are used to treat complications associated with metastatic brain tumours and their treatment. It has been suggested that these agents exert anticancer effec...Read More
Ya-Ting Kao, Xunmin Guo, Yi Yang, Zheyun Liu, Ali Hassanali, Qin-Hua Song, Lijuan Wang, Dongping Zhong
We report here our systematic characterization of a photoinduced electron-transfer (ET) redox cycle in a covalently linked donor-spacer-acceptor flexible system, consisting of N-acetyl-tryptophan meth...Read More
H L Carthew, J M Ziebell, R Vink
Inhibition of substance P (SP) activity through the use of NK1 receptor antagonists has been shown to be a promising neuroprotective therapy following traumatic brain injury (TBI). Conversely, recent ...Read More
Emma Thornton, Robert Vink
Neuroinflammation and blood brain barrier (BBB) dysfunction have been implicated in the pathogenesis of Parkinson's disease (PD). The neuropeptide substance P (SP) is an important mediator of bot...Read More
Liqiong L Fang, Rajesh R Parti, Peifeng P Hu
N-acetyltryptophan (NAT) has long been used as a stabilizer in some protein solutions, such as human serum albumin, to prevent oxidative protein degradation. However, the fate of NAT has not been disc...Read More
Jan J Stange, Melanie M Stiffel, Anne A Goetze, Sabrina S Strube, Juliane J Gruenert, Sebastian S Klammt, Steffen S Mitzner, Sebastian S Koball, Stefan S Liebe, Emil E Reisinger
Liver failure is associated with an accumulation of toxic molecules that exert an affinity to albumin. Some of them have vasoactive activity. So far, albumin has been used as a plasma expander to impr...Read More
Yu Ishima, Shuichi Hiroyama, Ulrich Kragh-Hansen, Toru Maruyama, Tomohiro Sawa, Takaaki Akaike, Toshiya Kai, Masaki Otagiri
S-Nitrosated human serum albumin (SNO-HSA) is a large molecular weight nitric oxide carrier in human plasma, and because of its many beneficial effects in different tests, it is currently under invest...Read More
P A PA Reine, U E UE Kongsgaard, A A Andersen, A-K AK Th?gersen, H H Olsen
In vitro and in vivo studies have indicated that stabilizers present in pharmaceutical-grade albumin influence the albumin-binding capacity for highly protein-bound drugs. However, the half-life of th...Read More
James J Donkin, Alan J Nimmo, Ibolja Cernak, Peter C Blumbergs, Robert Vink
Brain edema and swelling is a critical factor in the high mortality and morbidity associated with traumatic brain injury (TBI). Despite this, the mechanisms associated with its development are poorly ...Read More
Olga B OB Morozova, Alexey S AS Kiryutin, Alexandra V AV Yurkovskaya
The efficiency of the chemical pathway of DNA repair is studied by time-resolved chemically induced dynamic nuclear polarization (CIDNP) using the model system containing guanosyl base radicals, and t...Read More
Helmut G?rner
The photoreduction of 1,4-benzoquinone, 1,4-naphthoquinone, 9,10-anthraquinone (AQ) and several methylated or halogenated derivatives in argon-saturated acetonitrile-water mixtures by indole, N-acetyl...Read More
M Lehnig, M Kirsch
Tryptophan and melatonin are nitrated by peroxynitrite; tryptophan residues in proteins are susceptible to attack by reactive nitrogen species. Nitrated tryptophan might therefore be used as a biomark...Read More
Robert Vink, J J Donkin, M I Cruz, Alan J Nimmo, Ibolja Cernak
Magnesium (Mg) deficiency has been shown to increase substance P release and induce a pro-inflammatory response that can be attenuated with the administration of a substance P-antagonist. Neurogenic i...Read More
Makoto M Anraku, Yasufumi Y Tsurusaki, Hiroshi H Watanabe, Toru T Maruyama, Ulrich U Kragh-Hansen, Masaki M Otagiri
The capability of octanoate, N-acetyl-l-tryptophanate (N-AcTrp) and other ions of fatty acids and amino acids to stabilize human serum albumin (HSA) against thermal and oxidative stress was studied. N...Read More
Hassan H Abdoul-Carime, Sascha S Gohlke, Eugen E Illenberger
Secondary low-energy electrons are abundantly created during the early moments following the deposition of energy by radiation into cells. Here we show the ability of slow (<12 eV) electrons to eff...Read More
Toshinori T Suzuki, Howard F HF Mower, Marlin D MD Friesen, Isabelle I Gilibert, Tomohiro T Sawa, Hiroshi H Ohshima
Proteins are targets of reactive nitrogen species such as peroxynitrite and nitrogen dioxide. Among the various amino acids in proteins, tryptophan residues are especially susceptible to attack by rea...Read More
Russell R RR King, C Harold CH Lawrence, Jean J Embleton, Larry A LA Calhoun
Chemical and biochemical studies indicated the possible involvement of N-acetyltryptophan and 4-nitrotryptophan as intermediates in biosynthesis of the thaxtomin phytotoxins. A search for other potent...Read More
Jakub W?odarczyk, Borys Kierdaszuk
A power-like decay function, characterized by the mean excited-state lifetime and relative variance of lifetime fluctuation around the mean value, was applied in analysis of fluorescence decays measur...Read More
Michael M Kirsch, Anke A Fuchs, Herbert H de Groot
N(2)O(3) formed from nitric oxide in the presence of oxygen attacks thiols in proteins to yield S-nitrosothiols, which are believed to play a central role in NO signaling. In the present study we exam...Read More
S M SM Andrade, S M SM Costa
The spectroscopic properties of alpha-chymotrypsin (alpha-Chym), L-tryptophan (Trp) and N-acetyl-L-tryptophan (NAT) solubilized in hydrated reverse micelles of sodium bis(2-ethylhexyl) sulfosuccinate ...Read More
K M KM Meisenheimer, P L PL Meisenheimer, T H TH Koch
We're sorry this abstract is currently not available....Read More
T T Arakawa, Y Y Kita
Acetyltryptophanate (AT) and caprylate (Cap) have been used to stabilize serum albumin against heat treatment. However, the mechanism of stabilization by these additives has never been fully elucidate...Read More
K K Ruan, S S Tian, R R Lange, C C Balny
The high pressure effects on fluorescence of free tryptophan (Trp) and its derivatives, N-acetyl-tryptophan (AT), N-acetyl-tryptophanamide (NATA), tryptophanamide (TA), and tryptophan, containing 6-po...Read More
F F Peissker, L L Fischer
A covalent method to keep imprinted properties of proteins stable in aqueous as well as in organic environment is described. To stabilize the ligand induced acceptance for D-configured substrates by a...Read More

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