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1-(1-金刚烷基)乙基胺盐酸盐

产品编号 A118559 | CAS号 1501-84-4 | 阿拉丁
1-(1-Adamantyl)ethylamine hydrochloride
99%
组合的产品项目
货号 规格 库存 价格 数量
A118559-100g 99% 上海(预计3-5个工作日)
北方(预计3-5个工作日)
 
A118559-1g 99% 上海(>10)
北方(预计3-5个工作日)
 
A118559-25g 99% 上海(预计3-5个工作日)
北方(预计3-5个工作日)
 
A118559-5g 99% 上海(>10)
北方(预计3-5个工作日)
 
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属性

熔点 375°C

描述

别名 1-(1-金刚烷基)乙基胺盐酸盐 ;
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标识符号 GHS07 GHS07
信号词 Warning
警示性声明 P261,P305+P351+P338
危害声明 H302,H315,H319,H335
参考文献
Loren B Andreas, Alexander B Barnes, Bj?rn Corzilius, James J Chou, Eric A Miller, Marc Caporini, Melanie Rosay, Robert G Griffin
We demonstrate the use of dynamic nuclear polarization (DNP) to elucidate ligand binding to a membrane protein using dipolar recoupling magic angle spinning (MAS) NMR. In particular, we detect drug bi...Read More
Yuxin Zhang, Hujun Shen, Mingbo Zhang, Guohui Li
BM2 channel plays an important role in the replication of influenza virus B. However, few studies attempt to investigate the mechanism of the proton conductance in BM2 channel, as well as the drug res...Read More
Guang-Quan GQ Wang, Yan-Fang YF Qin, Li-Ming LM Du, Jun-Fei JF Li, Xu X Jing, Yin-Xia YX Chang, Hao H Wu
Amantadine hydrochloride (AMA) and rimantadine hydrochloride (RIM) are non-fluorescent in aqueous solutions. This property makes their determination through direct fluorescent method difficult. The co...Read More
V S VS Smirnov, V V VV Zarubaev, P M PM Anfimov, A A AA Shtro
The purpose of the study was to evaluate the modulating effect of glutamyl-tryptophan (EW), glycyrrhizic acid (GA), and their combination on the course of experimental infection caused by influenza A ...Read More
Loren B Andreas, Matthew T Eddy, James J Chou, Robert G Griffin
We report chemical shift assignments of the drug-resistant S31N mutant of M2(18-60) determined using 3D magic-angle-spinning (MAS) NMR spectra acquired with a (15)N-(13)C ZF-TEDOR transfer followed by...Read More
Tijana Ivanovic, Rutger Rozendaal, Daniel L Floyd, Milos Popovic, Antoine M van Oijen, Stephen C Harrison
M2 protein of influenza A viruses is a tetrameric transmembrane proton channel, which has essential functions both early and late in the virus infectious cycle. Previous studies of proton transport by...Read More
Sander A A SA Kooijmans, Danielle D Senyschyn, Muguntha M MM Mezhiselvam, Julia J Morizzi, Susan A SA Charman, Babette B Weksler, Ignacio-Andres IA Romero, Pierre-Olivier PO Couraud, Joseph A JA Nicolazzo
Despite their structural similarity, the two anti-influenza adamantane compounds amantadine (AMA) and rimantadine (RIM) exhibit strikingly different rates of blood-brain barrier (BBB) transport. Howev...Read More
Suelen F SF Sucena, Raphael E F RE Paiva, Camilla C Abbehausen, Ives B IB Mattos, Marcelo M Lancellotti, André L B AL Formiga, Pedro P PP Corbi
A novel gold(I) complex with rimantadine (RTD) was obtained and structurally characterized by a set of chemical and spectroscopic analysis. 1H, 13C and 15N nuclear magnetic resonance (NMR) and infrare...Read More
We're sorry this abstract is currently not available....Read More
Linh Tran, Sy Bing Choi, Belal O Al-Najjar, Muhammad Yusuf, Habibah A Wahab, Ly Le
The M2 channel protein on the influenza A virus membrane has become the main target of the anti-flu drugs amantadine and rimantadine. The structure of the M2 channel proteins of the H3N2 (PDB code 2RL...Read More
Rafal M RM Pielak, Kirill K Oxenoid, James J JJ Chou
The M2 channel of influenza A is a target of the adamantane family antiviral drugs. Two different drug-binding sites have been reported: one inside the pore, and the other is a lipid-facing pocket. A ...Read More
Georgina G Cirrincione-Dall, Barbara J BJ Brennan, Rosa M RM Ballester-Sanchis, Mercidita T MT Navarro, Brian E BE Davies
Preclinical data suggest increased antiviral activity and less viral resistance when neuraminidase inhibitors and adamantanes are used in combination to harness the complementary effects of their diff...Read More
Saumil S Doshi, Laurie L Kamimoto, Lyn L Finelli, Alejandro A Perez, Arthur A Reingold, Ken K Gershman, Kimberly K Yousey-Hindes, Kathryn K Arnold, Patricia P Ryan, Ruth R Lynfield, Craig C Morin, Joan J Baumbach, Emily B EB Hancock, Nancy M NM Bennett, S
The 2009 influenza pandemic led to guidelines emphasizing antiviral treatment for all persons hospitalized with influenza, including pregnant women. We compared antiviral use among adults hospitalized...Read More
George Atiee, Kenneth Lasseter, Sharon Baughman, Amy McCullough, Phil Collis, Alan Hollister, Jaime Hernandez
Peramivir, an intravenously administered neuraminidase inhibitor, may be used concomitantly with other influenza antivirals. Two studies were conducted to assess the potential for pharmacokinetic inte...Read More
I T IT Fediakina, M Iu MIu Shchelkanov, P G PG Deriabin, I A IA Leneva, N V NV Gudova, T V TV Kondrat'eva, D K DK L'vov
The data on cytotoxicity and antiviral activity of commercial antivirals, such as Remantadine, Oseltamivir, Arbidol and Ribavirin in the MDCK cell culture infected with highly pathogenic (H5N1) and pa...Read More
V G VG Belolipetskaia, S V SV Blagodatskikh, E A EA Zhabina, D A DA Kibalchich, D F DF Guranda, N A NA Belolipetski?, L I LI Rudenko
Comparative pharmacokinetics of anti-influenza drug composition Antigrippin-maximum administered in capsules and a powder for preparing solutions has been studied after single administraton in a group...Read More
G G U GG Rohde
Influenza infections have important socio-economic consequences. Risk groups identified so far include small children and elderly adults with comorbidities. In recent years in addition to seasonal inf...Read More
Bo OuYang, Shiqi Xie, Marcelo J Berardi, Xinhao Zhao, Jyoti Dev, Wenjing Yu, Bing Sun, James J Chou
The hepatitis C virus (HCV) has developed a small membrane protein, p7, which remarkably can self-assemble into a large channel complex that selectively conducts cations. We wanted to examine the stru...Read More
V A Shibnev, T M Garaev, M P Finogenova, E S Shevchenko, E I Burtseva
New adamantane derivatives with amino acid residues and other bifunctional compounds were synthesized and their antiviral activity towards influenza A(H1N1)pdm and A(H3N2) viruses was studied. Some of...Read More
Lora L Simeonova, Galina G Gegova, Angel S AS Galabov
The combined effect of rimantadine and oseltamivir in a prophylactic context (therapy beginning 4 h pre-virus infection) and therapeutic context (therapy started at 24 h post-viral inoculation) course...Read More
Jonathan Hsu, Nancy Santesso, Reem Mustafa, Jan Brozek, Yao Long Chen, Jessica P Hopkins, Adrienne Cheung, Gayane Hovhannisyan, Liudmila Ivanova, Signe A Flottorp, Ingvil Saeterdal, Arthur D Wong, Jinhui Tian, Timothy M Uyeki, Elie A Akl, Pablo Alonso-Coe
Systematic reviews of randomized, controlled trials in patients with influenza suggest a lack of evidence about the effects of antiviral therapy on several patient-important outcomes of influenza.To s...Read More
Márcia G Alves Galv?o, Marilene Augusta Rocha Crispino Santos, Antonio Jl Alves da Cunha
The effectiveness and safety of amantadine (AMT) and rimantadine (RMT) for preventing and treating influenza A in adults has been systematically reviewed. However, little is known about these treatmen...Read More
Mona Alqazzaz, Andrew J Thompson, Kerry L Price, Hans-Georg Breitinger, Sarah C R Lummis
The Gloeobacter ligand-gated ion channel (GLIC) is a bacterial homolog of vertebrate Cys-loop ligand-gated ion channels. Its pore-lining region in particular has a high sequence homology to these rela...Read More