|别名||γ-环糊精 ;Cyclomaltooctaose Cyclooctaamylose Schardinger γ-Dextrin|
|个人防护设备||Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter|
Nanoemulsions aimed at dermal drug delivery are usually stabilised by natural lecithins. However, lecithin has a high tendency towards self-aggregation and is prone to chemical degradation. Therefore,...Read More
Effect of γ-cyclodextrin on the in vitro skin permeation of a steroidal drug from nanoemulsions: impact of experimental setup.
Numerous reports on the enhancement effect of cyclodextrins (CDs) on the skin permeation of dermally applied drugs exist, the majority of which is based on in vitro diffusion cell studies. The specifi...Read More
Steady state and time resolved fluorescence along with anisotropy and induced circular dichroism (ICD) spectroscopy provide useful tools to observe and understand the behavior of the therapeutically i...Read More
Stochastic modeling of flexible biomolecules applied to NMR relaxation. I. Internal dynamics of cyclodextrins: γ-cyclodextrin as a case study.
In this work, we address the description of the dynamics of cyclodextrins in relation with nuclear magnetic resonance (NMR) relaxation data collected for hydroxymethyl groups. We define an integrated ...Read More
Supramolecular host-guest interactions of oxazine-1 dye with β- and γ-cyclodextrins: a photophysical and quantum chemical study.
Supramolecular host-guest interactions of oxazine-1 dye with β- and γ-cyclodextrins (βCD and γCD, respectively) have been investigated in neutral aqueous solution (pH ～ 7) at ambient temperature...Read More
[Effect of different water-soluble forms of the fullerene C60 on the metabolic activity and ultra-structure of cells in culture].
In view of contradictory data on the toxicity of fullerenes for live organisms we studied the effect of water-soluble complexes of C60 with N-polyvivyl-pirrolidone (C60/PVP) and gamma-cyclodextrine (C...Read More
The production of cyclodextrins (CDs) by cyclodextrin glycosyltransferase (CGTase) from Bacillus clarkii 7364 was studied. Forty-seven percent (w/w) conversion rate to γ-CD was obtained in the proces...Read More
Sulfadiazine-selective determination in aquaculture environment: selective potentiometric transduction by neutral or charged ionophores.
Solid-contact sensors for the selective screening of sulfadiazine (SDZ) in aquaculture waters are reported. Sensor surfaces were made from PVC membranes doped with tetraphenylporphyrin-manganese(III) ...Read More
Synthesis of γ-cyclodextrin/chitosan composites for the efficient removal of Cd(II) from aqueous solution.
The synthesis of chitosan-graft-γ-cyclodextrin (Ch-g-γ-CD) using persulfate/ascorbic acid redox system was done and characterized by FTIR, XRD, TGA and SEM/EDX. The optimum yield of the copolymer wa...Read More
Although 3α-hydroxy, 5α-reduced pregnane steroids, such as allopregnanolone (AlloP) and tetrahydrodeoxycorticosterone, are endogenous positive modulators of postsynaptic GABA(A) receptors, the funct...Read More
Ginseng is one of the most popular functional ingredients found in energy drink formulations. Although ginseng is known for its health benefits, ginseng is also notorious for imparting a bitter taste....Read More
Uni-molecular detection and quantification of selected β-lactam antibiotics with a hybrid α-hemolysin protein pore.
Single-nanopores have recently been used to electrically detect a wide range of analytes. Similarly, using electrophysiology, we demonstrate how a system comprised of an ion channel formed by α-hemol...Read More
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yCD/HPyCD mixtures as solubilizer: solid-state characterization and sample dexamethasone eye drop suspension.
Study the complexation of dexamethasone in combinations of γ-cyclodextrin (γCD) and 2-hydroxypropyl-γ-cyclodextrin (HPγCD) with emphasis on solid characterization and development of aqueous dexame...Read More
Three types of cyclodextrin nanosponges were synthetized cross-linking @a, @b or @c cyclodextrin with carbonyldiimidazole as cross-linker. Nanosponges are solid nanoparticles previously used as drug c...Read More
Fluorescent γ-cyclodextrin derivatives, modified using N-phenyl-x-anthracenecarboxamido (ACs; x = 9, 1), were synthesized and investigated using fluorescence and UV-vis spectroscopy. Fluorescence en...Read More
Amphotericin B (AmB) is a wide spectrum antifungal with low incidence of clinical resistance. However, there are no licensed topical formulations with AmB in most developed countries. Extemporaneous p...Read More
Purification and characterization of a liquefying α-amylase from alkalophilic thermophilic Bacillus sp. AAH-31.
α-Amylase (EC 184.108.40.206) hydrolyzes an internal α-1,4-glucosidic linkage of starch and related glucans. Alkalophilic liquefying enzymes from Bacillus species are utilized as additives in dishwashing a...Read More
Supramolecular hydrogels formed by pyrene-terminated poly(ethylene glycol) star polymers through inclusion complexation of pyrene dimers with γ-cyclodextrin.
Novel supramolecular hydrogels were formed between pyrene-terminated poly(ethylene glycol) star polymers and γ-cyclodextrin (γ-CD), through the inclusion complexation of dimers of the pyrene termina...Read More
Formation of a polypseudorotaxane via self-assembly of γ-cyclodextrin with poly(N-isopropylacrylamide).
A polypseudorotaxane (PPR) comprising γ-cyclodextrin (γ-CD) as host molecules and poly(N-isopropylacrylamide) (PNIPAM) as a guest polymer is prepared via self-assembly in aqueous solution. Due to th...Read More
Chiral recognition of dapoxetine enantiomers with methylated-gamma-cyclodextrin: A validated capillary electrophoresis method
The enantiomers of dapoxetine, a serotonin transporter inhibitor for the treatment of premature ejaculation have been separated by cyclodextrin modified capillary zone electrophoresis using uncoated f...Read More
Biological effects of water-soluble inclusion complexes of fullerene C60 with poly(vinyl pyrrolidone) (C60/PVP) and gamma-cyclodextrin (C60/g-CD) as well as solid C60 (C60-coated surface) on cell viab...Read More
We describe a novel anisotropic supramolecular gel made of cyclodextrin-dye, in which physical gelation is completed by lithium salt. Rheological experiment reveals the elastic behaviors of the hydrog...Read More
Cooperative binding and stabilization of the medicinal pigment curcumin by diamide linked γ-cyclodextrin dimers: a spectroscopic characterization.
Diamide linked γ-cyclodextrin (γ-CD) dimers are used to capture curcumin and suppress its decomposition in water. In this study, succinamide and urea linked γ-CD dimers joined through the C6(A) car...Read More
Characterization of room temperature phosphorescence of propranolol and the chiral discrimination between R- and S-isomers.
Upon addition of a small amount of bromocyclohexane, propranolol displays room temperature phosphorescence in γ-cyclodextrin solution without deoxygenation. Several factors including the pH, and the ...Read More