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N-氯代琥珀酰亚胺

¥ 53.46

产品编号 C105072 | CAS号 128-09-6 | 阿拉丁
N-Chlorosuccinimide
98%
组合的产品项目
货号 规格 库存 价格 数量
C105072-100g 98% 上海(>10)
北方(6)
 
C105072-2.5kg 98% 上海(预计3-7周)
北方(预计3-7周)
 
C105072-25g 98% 上海(预计3-7周)
北方(预计3-7周)
 
C105072-500g 98% 上海(预计3-7周)
北方(预计3-7周)
 
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属性

敏感性 对热、光和湿度敏感
密度 1.5000
熔点 148-150°C
存贮条件 充氩保存

描述

产品介绍 溶解度:14 g/L水 (20°C)、1g/150ml 乙醇 和1g/50ml 苯,,稍溶于醚、氯仿和四氯化碳,溶于丙酮。1:50水溶液对石蕊呈酸性。有氯的气味
别名 N-氯代琥珀酰亚胺; N-氯代丁二酰亚胺; 琥珀酰氯亚胺; N-氯丁二酰亚胺; 琥珀酰基氯亚胺; N-氯代二乙酰亚胺; NCS(N-氯代琥珀酰亚胺); 氯代丁二酰亚胺;NCS; Chlorosuccinimide; Succinchlorimide; 1-Chloro-2,5-pyrrolidinedione
应用 有机合成中作氯化剂,抗菌素药物的中间体。
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标识符号 GHS05 GHS05, GHS07 GHS07
信号词 Danger
风险声明 (欧洲) R22;R34
安全声明(欧洲) S26;S36/37/39;S45
警示性声明 P280,P305+P351+P338,P310
危害码(欧洲) C
危害声明 H302,H314
个人防护设备 Eyeshields,Faceshields,full-face particle respirator type N100 (US),Gloves,respirator cartridge type N100 (US),type P1 (EN143) respirator filter,type P3 (EN 143) respirator cartridges
RTECS UY1013500
WGK德国 3
Merck Index 2164
UN代码 3261
参考文献
Tobias M Postma, Fernando Albericio
N-Chlorosuccinimide is described as a widely applicable on-resin disulfide-forming reagent. Disulfide bond formation was completed within 15 min in DMF. This strategy was successfully used in the synt...Read More
Jun-Hao Cheng, Chintakunta Ramesh, Hsin-Lun Kao, Yu-Jen Wang, Chien-Ching Chan, Chin-Fa Lee
A convenient one-pot approach for the synthesis of aryl sulfides through the coupling of thiols with Grignard reagents in the presence of N-chlorosuccinimide is described. The sulfenylchlorides were f...Read More
David A Foley, Christopher W Doecke, Jonas Y Buser, Jeremy M Merritt, Linda Murphy, Marie Kissane, Stuart G Collins, Anita R Maguire, Andreas Kaerner
On-flow ReactIR and (1)H NMR reaction monitoring, coupled with in situ intermediate characterization, was used to aid in the mechanistic elucidation of the N-chlorosuccinimide mediated transformation ...Read More
Timothy J Barker, Elizabeth R Jarvo
We're sorry this abstract is currently not available....Read More
David I Pattison, Robert J O’Reilly, Ojia Skaff, Leo Radom, Robert F Anderson, Michael J Davies
Hypochlorous (HOCl) and hypobromous (HOBr) acids are strong bactericidal oxidants that are generated by the human immune system but are implicated in the development of many human inflammatory disease...Read More
Sam S Alam, Zhenjun Z Li, Sabina S Janciauskiene, Ravi R Mahadeva
The acceleration of chronic obstructive pulmonary disease (COPD) by cigarette smoke (CS) in individuals with severe genetic deficiency of α(1)-antitrypsin (Z-AT [Glu342Lys]) exemplifies the critical ...Read More
Ahmad Khoramabadi-zad, Azam Shiri, Fateme Derakhshan-Panah, Zahra Salimi
Two N-chloro reagents (chloramine-T and N-chlorosuccinimide) were used as effective oxidizing agents for the oxidation of bisnaphthols to the corresponding Abel's ketones under mild and convenien...Read More
Mohammad Ali MA Karimi, Mohammad M Mazloum Ardakani, Hamid H Abdollahi, Fatemeh F Banifatemeh
Simultaneous determination of hydrazine (HZ) and phenylhydrazine (PHZ) by H-point standard addition method (HPSAM) and partial least squares (PLS) regression was carried out based on kinetic data from...Read More
A A Safavi, M A MA Karimi, M R Hormozi MR Nezhad
A chemiluminescent method for the determination of riboflavin is described. The method is based on the chemiluminescence (CL) generated during the oxidation of luminol by N-bromosuccinimide (NBS) and ...Read More
Afsaneh A Safavi, Mohammad Ali MA Karimi, Mohammad Reza Hormozi MR Nezhad
A chemiluminescent method for the determination of isoniazid is described. Method is based on the chemiluminescence (CL) generated during the oxidation of luminol by N-bromosuccinimide (NBS) and N-chl...Read More
T T Kikuchi, T T Abe, M M Yaekashiwa, Y Y Tominaga, H H Mitsuhashi, K K Satoh, T T Nakamura, T T Nukiwa
Secretory leukoprotease inhibitor (SLPI), an 11.7-kD nonglycosylated serine protease inhibitor, is produced and released into the fluids of mucosal surfaces including human lung. It comprises two doma...Read More
B Pliszka, E Karczewska, B Wawro
Structural changes in subfragment 1 of skeletal muscle myosin were investigated by cross-linking trypsin-cleaved S1 with 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide. In the absence of nucleotide the...Read More
Santhosh Reddy Mandha, Manjula Alla, Vittal Rao Bommena, Jagadeesh Babu Nanubolu, Santosh Kumar Lingala, Soujanya Yarasi
Oxidative difunctionalization of 2-amino-4H-pyrans was accomplished with iodobenzene diacetate (IBD) and N-chlorosuccinimide (NCS) reagents in alcoholic medium. 2-Amino-4H-pyrans undergo geminal dialk...Read More
Hiren H Banerjee, Ravinder R Singh
A large number of proteins contain multiple RNA recognition motifs (RRMs). How multiple RRMs contribute to RNA recognition in solution is, however, poorly understood. Here, we describe a simple bioche...Read More
Lan G LG Coffman, Julie C JC Brown, David A DA Johnson, Narayanan N Parthasarathy, Ralph B RB D'Agostino, Mark O MO Lively, Xiaoyang X Hua, Stephen L SL Tilley, Werner W Muller-Esterl, Mark C MC Willingham, Frank M FM Torti, Suzy V SV Torti
Ferritin is a protein principally known for its role in iron storage. We have previously shown that ferritin can bind high-molecular-weight kininogen (HK). Upon proteolytic cleavage by the protease ka...Read More
Luca L Bernardi, Karl Anker KA J?rgensen
The direct chiral Lewis acidic enantioselective chlorination and fluorination of beta-keto phosphonates is presented; the chlorination proceeds in high yields and with up to 94% ee using NCS as the ch...Read More
D K DK Mulkey, R A RA Henderson, N A NA Ritucci, R W RW Putnam, J B JB Dean
We're sorry this abstract is currently not available....Read More
Magdalena M Niezio?ek, Marcin M Kot, Krzysztof K Pyka, Pawe? P Mak, Andrzej A Kozik
Kininogens are multifunctional proteins involved in a variety of regulatory processes including the kinin-formation cascade, blood coagulation, fibrynolysis, inhibition of cysteine proteinases etc. A ...Read More
M M Demeule, A A Laplante, G F GF Murphy, R M RM Wenger, R R Béliveau
The binding site of cyclosporin A to P-glycoprotein was characterized by using a multidrug-resistant Chinese hamster ovary cell line. P-glycoprotein photolabeled with diazirine-cyclosporin A analogue ...Read More