|溶解性||Soluble in water (145 mg/ml at 20 °C). Insoluble in ethanol, and acetone.|
|产品介绍||水溶解度为 14.5g /100ml ，不溶于乙醇，乙醚等有机溶剂。熔融时开始分解，是一种天然包接剂。|
|别名||环六糖;环状麦芽六糖;α-环状糊精;环己烷直链淀粉;环麦芽六糖;α-Schardinger dextrin; Cyclohexaamylose; Cyclomaltohexaose; Schardinger α-Dextrin|
|应用||A naturally occuring clathrate.|
|个人防护设备||Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter|
Cholera toxin (CT), the principal virulence factor secreted by Vibrio cholerae, is an A-B5 type exotoxin that binds to host cell GM1-gangliosides and is responsible for cholera diarrhoea. We tested th...Read More
Photoreversible micelles were achieved by a combination of commercially available components sodium alginate (Alg), tetradecyltrimethylammonium bromide (TTAB), α-cyclodextrin (α-CD), and 4-(phenylaz...Read More
Fabrication of novel coumarin derivative functionalized polypseudorotaxane micelles for drug delivery.
The fabrication and drug delivery of novel polypseudorotaxane micelles with small molecule coumarin derivative as hydrophobic segment were reported. 7-Carboxymethoxy coumarin was immobilized on the te...Read More
The development of stimulus-responsive polymeric materials is of great importance, especially for the development of remotely manipulated materials not in direct contact with an actuator. Here we desi...Read More
Highly porous polystyrene-block-poly(4-vinylpyridine) (PS-b-P4VP) diblock copolymer membranes are prepared using carbohydrates as additives. Therefore α-cyclodextrine, α-(D)-glucose, and saccharose ...Read More
The hollow mesoporous silica nanoparticles (HMSNs), which have been used as the nanocontainers for the corrosion inhibitor, benzotriazole, were fabricated using the hard-template method. Alkaline-resp...Read More
Unraveling unidirectional threading of α-cyclodextrin in a rotaxane through spin labeling approach.
We present here the results of a CW-ESR investigation of a double spin labeled α-cyclodextrin-based rotaxane that is characterized by the presence of nitroxide labels both at the wheel and at the ...Read More
Gold nanorods (AuNRs) stabilized by cetyltrimethylammonium bromide (CTAB) were deposited onto crystals of α-cyclodextrin (α-CD) inclusion compounds (ICs) that contained octanethiol (OT) as guest mol...Read More
Folate-PEG-appended dendrimer conjugate with α-cyclodextrin as a novel cancer cell-selective siRNA delivery carrier.
We previously reported that of the various polyamidoamine (PAMAM) STARBURST dendrimer (generation 3, G3) (dendrimer) conjugates with cyclodextrins (CyDs), the dendrimer (G3) conjugate with α-CyD havi...Read More
A quantitative study of intrinsic non-covalent interactions within complexes of α-cyclodextrin and benzoate derivatives.
A novel deconvolution method for energy-resolved reaction cross sections is applied to determine intrinsic gas-phase dissociation energies for non-covalent α-cyclodextrin host-guest complexes. M06-2X...Read More
α-Cyclodextrin dimer complexes of dopamine and levodopa derivatives to assess drug delivery to the central nervous system: ADME and molecular docking studies.
This paper attempts to predict and emphasize molecular interactions of dopamine, levodopa, and their derivatives (Dopimid compounds) containing 2-phenyl-imidazopyridine moiety with the α-cyclodextrin...Read More
Formulations based on alpha cyclodextrin and soybean oil: an approach to modulate the oral release of lipophilic drugs.
The purpose of this work was to investigate the potential of α-cyclodextrin combined to soybean oil-based formulations to modulate the release of a model drug, indomethacin. Dry emulsion, naked and c...Read More
Systemic delivery of transthyretin siRNA mediated by lactosylated dendrimer/α-cyclodextrin conjugates into hepatocyte for familial amyloidotic polyneuropathy therapy.
RNA interference (RNAi) is a sequence-specific gene-silencing mechanism triggered by double-stranded RNA and powerful tools for a gene function study and RNAi therapy. Although siRNAs offer several ad...Read More
Potential use of lactosylated dendrimer (G3)/α-cyclodextrin conjugates as hepatocyte-specific siRNA carriers for the treatment of familial amyloidotic polyneuropathy.
To reveal the potential use of lactosylated-dendrimer (G3) conjugates with α-cyclodextrin (Lac-α-CDE (G3)) as novel hepatocyte-specific siRNA carriers in order to treat transthyretin (TTR)-related f...Read More
Safe and effective gene delivery is essential to the success of gene therapy. We synthesized and characterized a novel nonviral gene delivery system in which folate (FA) molecules were functioned as b...Read More
Structure determination of fexofenadine-α-cyclodextrin complex by quantitative 2D ROESY analysis and molecular mechanics studies.
Complexation of fexofenadine with α-cyclodextrin in aqueous medium was studied. The stoichiometry of the resulting inclusion complex was determined by (1) H NMR titration data. 2D ROESY data provided...Read More
Potential use of folate-polyethylene glycol (PEG)-appended dendrimer (G3) conjugate with α-cyclodextrin as DNA carriers to tumor cells.
We previously reported that polyamidoamine STARBURST dendrimer (generation 3, G3) (dendrimer) conjugate with α-cyclodextrin (α-CyD) having an average degree of substitution of 2.4 of α-CyD (α-CDE)...Read More
Possible enhancing mechanisms for gene transfer activity of glucuronylglucosyl-β-cyclodextrin/dendrimer conjugate.
We previously reported that glucuronylglucosyl-β-cyclodextrin (GUG-β-CyD) conjugate with polyamidoamine starburst dendrimer (GUG-β-CDE conjugate) with the average degree of substitution (DS) of cyc...Read More
Application of time-of-flight aerosol mass spectrometry for the online measurement of gaseous molecular iodine.
Here we present a new application of a time-of-flight aerosol mass spectrometer (TOF-AMS) for the measurement of atmospheric trace gases in real-time. Usually, TOF-AMS instruments are not sensitive to...Read More
Supermolecular quantum dots (QDs) nanofluids have been firstly proposed and synthesized by virtue of the strong inclusion interactions between α-cyclodextrin (α-CD) and polyethylene glycol (PEG) cha...Read More
We're sorry this abstract is currently not available....Read More
Photoconductive properties of a π-conjugated α-cyclodextrin containing rotaxane and its corresponding molecular dumbbell.
The photoconductive properties of an azo-containing rotaxane, bearing a π-conjugated axial part and its corresponding dumbbell compound are investigated. Structural effects on the observed photoco...Read More
Cations in a molecular funnel: vibrational spectroscopy of isolated cyclodextrin complexes with alkali metals.
The benchmark inclusion complexes formed by α-cyclodextrin (αCD) with alkali-metal cations are investigated under isolated conditions in the gas phase. The relative αCD-M(+) (M=Li(+) , Na(+) , K(+...Read More
An initial investigation into the anti-inflammatory activity and antioxidant capacity of alpha-cyclodextrin-complexed Manuka honey.
The bioactive properties of Manuka honey are now well recognised, but the nature of honey (a sticky, viscous fluid) can make it hard to use as a health remedy. A new technology using encapsulation of ...Read More
The formation of effective and precise linkages in bottom-up or top-down processes is important for the development of self-assembled materials. Self-assembly through molecular recognition events is a...Read More