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N,N'-羰基二咪唑(CDI)

产品编号 C109315 | CAS号 530-62-1 | 阿拉丁
N,N'-Carbonyldiimidazole
99%
组合的产品项目
货号 规格 库存 价格 数量
C109315-100g 99% 上海(3)
北方(预计3-5个工作日)
 
C109315-1kg 99% 上海(5)
北方(预计3-5个工作日)
 
C109315-25g 99% 上海(8)
北方(预计3-5个工作日)
 
C109315-500g 99% 上海(预计3-7周)
北方(预计3-7周)
 
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属性

敏感性 易吸潮
密度 1.3030
熔点 117-122°C
溶解性 溶于二甲基甲酰胺(DMF)和水(与水反应)。
存贮条件 储存温度2-8℃,充氩保存

描述

产品介绍 接触空气易变质,遇水在几分钟内即水解,并释放出CO2。不溶于水,溶于乙醇、醚等有机溶剂,中度溶于THF.
别名 N,N'-羰基二咪唑(CDI);羰基咪唑;1,1'-羰基二咪唑;CDI;CDI; 1,1'-Carbonyldiimidazole
应用 多肽试剂,用于生化合成基团保护及蛋白质肽链的连接。作为合成三磷核苷、肽、和酯类的缩合剂;以及是合成酰基咪唑和吡藜酰胺的重要中间体。
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标识符号 GHS05 GHS05, GHS07 GHS07
信号词 Danger
风险声明 (欧洲) R22;R34
安全声明(欧洲) S26;S36/37/39;S45
警示性声明 P280,P305+P351+P338,P310
危害码(欧洲) C
危害声明 H302,H314
个人防护设备 Eyeshields,Faceshields,full-face particle respirator type N100 (US),Gloves,respirator cartridge type N100 (US),type P1 (EN143) respirator filter,type P3 (EN 143) respirator cartridges
WGK德国 2
Merck Index 1819
UN代码 3263
参考文献
Roberta Cavalli, Ansari Khalid Akhter, Agnese Bisazza, Pierangela Giustetto, Francesco Trotta, Pradeep Vavia
Three types of cyclodextrin nanosponges were synthetized cross-linking @a, @b or @c cyclodextrin with carbonyldiimidazole as cross-linker. Nanosponges are solid nanoparticles previously used as drug c...Read More
Laura Faiella, Fabrizio Dal Piaz, Angela Bisio, Alessandra Tosco, Nunziatina De Tommasi
Clerodane diterpenoids are a class of naturally occurring molecules widely distributed in the Lamiaceae family. Neo-clerodane diterpenoids from Salvia ssp were recently described as compounds inhibiti...Read More
Subash C B SC Gopinath, Koichi K Awazu, Makoto M Fujimaki, Kazufumi K Shimizu, Wataru W Mizutani, Kiyomi K Tsukagoshi
The surfaces of silica-based sensor chips, designed for evanescent-field-coupled waveguide-mode sensors, were functionalized using various surface chemistries. The immobilization of molecular entities...Read More
A A Sousa, C T CT Tomaz, F F Sousa, J A JA Queiroz
The growing demand on plasmid DNA (pDNA) manufacture for therapeutic applications requires a final product with higher quality and quantity, spending the least time. Most of the current processes for ...Read More
N V NV Roik, L A LA Belyakova
Surface grafting of β-cyclodextrin onto aminopropylsilica has been carried out under mild conditions using 1,1'-carbonyldiimidazole as an activator. The obtained β-cyclodextrin-silica has been ...Read More
B B Vasantha, T M TM Vishwanatha, Vommina V VV Sureshbabu
Synthesis of Nα-protected amino acyl azides starting from corresponding acids via the carbonyldiimidazole (CDI) activation is described. The protocol is extended for a one-pot preparation of ureido p...Read More
Danny D Lafrance, Paul P Bowles, Kyle K Leeman, Robert R Rafka
Malonic acid derivatives undergo unusually mild decarboxylation when treated with N,N'-carbonyldiimidazole (CDI) at room temperature to generate the carbonyl imidazole moiety in high yield, which...Read More
Karolina K Schickle, Kristin K Zurlinden, Christian C Bergmann, Markus M Lindner, Armin A Kirsten, Markus M Laub, Rainer R Telle, Herbert H Jennissen, Horst H Fischer
A functionalization is required for calcium phosphate-based bone substitute materials to achieve an entire bone remodeling. In this study it was hypothesized that a tailored composite of tricalcium ph...Read More
Raquel R Gon?alves, Maria Cristina Lopes MC Martins, Maria José MJ Oliveira, Gra?a G Almeida-Porada, Mário Adolfo MA Barbosa
Last trends in Biomaterials focus the mimic of cellular environments capable to control cellular responses. Epidermal growth factor (EGF) is a pleiotropic cytokine known to regulate cell proliferation...Read More
Claude Larrive?e-Aboussafy, Brian P Jones, Kristin E Price, Mark A Hardink, Robert W McLaughlin, Brett M Lillie, Joel M Hawkins, Rajappa Vaidyanathan
We're sorry this abstract is currently not available....Read More
Joana Carvalho, Susana Moreira, Jo?o Maia, Francisco M Gama
We're sorry this abstract is currently not available....Read More
Virgil V Percec, Mihai M Peterca, Michael E ME Yurchenko, Jonathan G JG Rudick, Paul A PA Heiney
Twin-dendritic organogelators have been prepared through selective functionalization of N-(3-aminopropyl)-1,3-propanediamine (APPDA) with self-assembling dendrons by using 1,1'-carbonyldiimidazol...Read More
Akon A Higuchi, Mayu M Sekiya, Yumiko Y Gomei, Masaru M Sakurai, Wen-Yih WY Chen, Satsuki S Egashira, Yuki Y Matsuoka
Cell separation from peripheral blood was investigated using polyurethane (PU) foam membranes having 5.2 mum pore size and coated with Pluronic F127 or hyaluronic acid. The permeation ratio of hematop...Read More
Hye Jin HJ Lee, Dobrin D Nedelkov, Robert M RM Corn
This paper describes a simple methodology for the creation of high-density multiplexed antibody arrays on gold surfaces that can be used to detect low molecular weight protein biomarkers with surface ...Read More
Akon A Higuchi, Nobuo N Aoki, Taro T Yamamoto, Toyohiko T Miyazaki, Hisashi H Fukushima, Tae Moon TM Tak, Shin S Jyujyoji, Satsuki S Egashira, Yuki Y Matsuoka, Shizue Hayashi SH Natori
The Pluronic F68 and F127, a triblock copolymer of ethylene oxide and propylene oxide, was activated using carbonyldiimidazole (CDI), and CDI-activated Pluronic F68 and F127 was subsequently immobiliz...Read More
Renata Marcia RM de Figueiredo, Roland R Fr?hlich, Mathias M Christmann
Amino alcohols are important synthons for N-heterocycles. We have developed an efficient method to activate hydroxyl groups, which avoids the use of toxic reagents and tolerates a wide variety of func...Read More
Thomas-Xavier Métro, Julien Bonnamour, Thomas Reidon, Jordi Sarpoulet, Jean Martinez, Frédéric Lamaty
The synthesis of various amides has been realised avoiding the use of any organic solvent from activation of carboxylic acids with CDI to isolation of the amides. Mechanochemistry was the key point of...Read More
Mei M Yan, Shenguang S Ge, Weiqiang W Gao, Chengchao C Chu, Jinghua J Yu, Xianrang X Song
A novel, simple and highly sensitive amplified fluorescence label-free immunosensor by using p-acid-encapsulated silica nanomaterials has been developed for the first time. 4,4'-(2,5-Dimethoxy-1,...Read More
M Cristina L Martins, Vanessa Ochoa-Mendes, Gisela Ferreira, Judite N Barbosa, Scott A Curtin, Buddy D Ratner, Mário A Barbosa
Surfaces that bind heparin are important for biomaterials for blood deheparinization. In our recent work it was demonstrated that a polypeptide composed of L-lysine and L-leucine (pKL), after immobili...Read More
Jenny J Ho, Fatin M Nawwab FM Al-Deen, Aswan A Al-Abboodi, Cordelia C Selomulya, Sue D SD Xiang, Magdalena M Plebanski, Gareth M GM Forde
Particulates with specific sizes and characteristics can induce potent immune responses by promoting antigen uptake of appropriate immuno-stimulatory cell types. Magnetite (Fe"3O"4) nanopart...Read More
Hye-Mi So, Dong-Won Park, Hyunju Chang, Jeong-O Lee
In this chapter, we discuss in detail the fabrication of carbon nanotube biosensors that use a single-walled carbon nanotube field-effect transistor (SWNT-FET) as a transducer, and aptamers as molecul...Read More
Xiang X Wang, Brandon S BS Imber, Stuart L SL Schreiber
Affinity purification of interacting proteins from cellular extracts is a powerful technique for identifying the cellular targets of small molecules. Affinity matrix-based small-molecule reagents are ...Read More
Thomas Heinze, Matthias Pohl, Jens Schaller, Frank Meister
Novel bulky esters of cellulose were synthesized homogeneously, applying the solvent systems DMA/LiCl or DMSO/TBAF, by conversion of the biopolymer with aryl polyester dendrons. The carboxylic acid mo...Read More
Arthur L AL Weber
A new method was developed for the synthesis of peptide thioesters from free amino acids and thiols in water. This one-pot simple method involves two steps: (1) activation in water of an amino acid pr...Read More
Fabrizio Picotti, Matteo Fabbian, Rita Gianni, Alessandra Sechi, Luca Stucchi, Marco Bosco
The synthesis and physicochemical characterisation of mixed lipoic and formic esters of hyaluronan (Lipohyal) are presented in this paper. The synthesis was conducted by activating lipoic acid with 1,...Read More
M T MT Hearn, G S GS Bethell, J S JS Ayers, W S WS Hancock
The use of 1,1'-carbonyldiimidazole-activated agarose for biospecific affinity chromatography is described. Activation of agarose with this carbonylating reagent gives a matrix devoid of addition...Read More
Stefanie S Van Trappen, Tjhing-Lok TL Tan, Jifang J Yang, Joris J Mergaert, Jean J Swings
Seven novel, cold-adapted, strictly aerobic, facultatively oligotrophic strains, isolated from Antarctic sea water, were investigated by using a polyphasic taxonomic approach. The isolates were Gram-n...Read More
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Consolidated evidence highlights the importance of redox signalling in poising the balance between self-renewal and differentiation in adult stem cells. The present study shows that human hematopoieti...Read More
Antonio Díaz-Cruz, Raquel Guinzberg, Ruy Guerra, Magdalena Vilchis, Daniel Carrasco, Francisco J García-Vázquez, Enrique Pi?a
It is known that adrenaline promotes hydroxyl radical generation in isolated rat hepatocytes. The aim of this work was to investigate a potential role of NADPH oxidase (Nox) isoforms for an oxidative ...Read More
Donald McCrann, Dan Yang, Hongjie Chen, Shannon Carroll, Katya Ravid
Our recent reports indicated that polyploidization of aortic vascular smooth muscle cells (VSMC) serves as a biomarker for aging, and that the polyploid state is linked to a higher incidence of senesc...Read More