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N-(5-氯-2-吡啶基)双(三氟甲烷磺酰亚胺)

产品编号 C121606 | CAS号 145100-51-2 | Aladdin
N-(5-Chloro-2-pyridyl)bis(trifluoromethanesulfonimide)
99%
  • 分子式 C7H3ClF6N2O4S2
  • 分子量392.68
  • Beilstein号 5833971
  • MDL号 MFCD00191833
  • PubChem编号 24865208
组合的产品项目
货号 规格 库存 价格 数量
C121606-1g 99% 上海(>10)
北方(预计3-5个工作日)
 
C121606-25g 99% 上海(1)
北方(预计3-5个工作日)
 
C121606-5g 99% 上海(4)
北方(预计3-5个工作日)
 
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属性

敏感性 对湿度敏感
熔点 44-47°C

描述

产品介绍 Reactant for: Suzuki-Miyaura cross coupling Synthesis of nicotinic acetylcholine receptor-selective ligands Enantioselective desymmetrizing palladium catalyzed carbonylation reactions Synthesis of high affinity niacin receptor GPR109A agonists Preparation of heteroaromatics
别名 2-[N,N-双(三氟甲基磺酰)氨基]-5-氯吡啶[三氟甲基磺酰化试剂];N,N-双(三氟甲基磺酰)-5-氯-2-吡啶胺; Comins 试剂;2-[双(三氟甲烷磺酰)亚氨基]-5-氯吡啶;2-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine;N-(5-Chloro-2-pyridyl)triflimide;Comins Triflating Reagent;
应用 用于由对应的酮烯醇化物或二烯醇化物生成高产率的三氟甲磺酸乙烯酯。
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标识符号 GHS07 GHS07
信号词 Warning
风险声明 (欧洲) R36/37/38
安全声明(欧洲) S26,S36
警示性声明 P261,P305+P351+P338
危害声明 H315,H319,H335
个人防护设备 dust mask type N95 (US), Eyeshields, Gloves
WGK德国 3
参考文献
Nurulain Zaveri, Faming Jiang, Cris Olsen, Willma Polgar, Lawrence Toll
Antagonist activity at the α3β4 nicotinic acetylcholine receptor (nAChR) is thought to contribute to the antiaddictive properties of several compounds. However, truly selective ligands for the α3β...Read More
Simon J SJ Byrne, Anthony J AJ Fletcher, Paul P Hebeisen, Michael C MC Willis
A desymmetrization protocol has been used to develop a palladium catalyzed enantioselective carbonylation process. Achiral cyclic bis-alkenyltriflates are converted to their corresponding monoester de...Read More
Fa-Xiang Ding, Hong C Shen, Larrisa C Wilsie, Mihajlo L Krsmanovic, Andrew K Taggart, Ning Ren, Tian-Quan Cai, Junying Wang, Xinchun Tong, Tom G Holt, Qing Chen, M Gerard Waters, Milton L Hammond, James R Tata, Steven L Colletti
A series of pyrazolyl propionyl cyclohexenamides were discovered as full agonists for the high affinity niacin receptor GPR109A. The structure-activity relationship (SAR) studies were aimed to improve...Read More