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N,N′-二异丙基碳二亚胺(DIC)

产品编号 D106162 | CAS号 693-13-0 | 阿拉丁
N,N'-Diisopropylcarbodiimide
98%
组合的产品项目
货号 规格 库存 价格 数量
D106162-100ml 98% 上海(>10)
北方(预计3-5个工作日)
 
D106162-25ml 98% 上海(>10)
北方(预计3-5个工作日)
 
D106162-500ml 98% 上海(4)
北方(预计3-5个工作日)
 
D106162-5ml 98% 上海(预计3-7周)
北方(预计3-7周)
 
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属性

敏感性 对湿度敏感
折光率 1.433
密度 0.8150
沸点 145-148°C
存贮条件 充氩保存

描述

产品介绍 N,N′-Diisopropylcarbodiimide is an alternative to dicyclohexylcarbodiimide in peptide synthesis.
别名 二异丙基碳化二亚胺;二异丙基碳酰亚胺;DIPCI; DIC;DIPCI; DIC
应用 A reagent for peptide synthesis.
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标识符号 GHS02 GHS02, GHS05 GHS05, GHS06 GHS06, GHS08 GHS08
信号词 Danger
风险声明 (欧洲) R10;R26;R41;R36/37/38;R42/43
安全声明(欧洲) S26;S36/37/39;S45
警示性声明 P260,P280,P284,P305+P351+P338,P310
危害码(欧洲) T
危害声明 H226,H315,H317,H318,H330,H334,H335
个人防护设备 Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
WGK德国 3
闪点(摄氏) 31 °C
UN代码 2929
参考文献
Inok I Surh, Mamta M Behl, Susan A SA Elmore, Rajendra S RS Chhabra
Dicyclohexylcarbodiimide (DCC) and Diisopropylcarbodiimide (DIC) are two representative chemicals in the carbodiimide class of chemicals used in industry as stabilizing agents. There is a potential of...Read More
J S McMurray, C A Lewis, N U Obeyesekere
Head-to-tail cyclization of peptides attached to insoluble supports by means of the side chains of aspartic acid or glutamic acid allows the rapid synthesis of cyclic peptides of widely varied amino a...Read More
Adam B AB Weinglass, Misha M Soskine, Jose-Luis JL Vazquez-Ibar, Julian P JP Whitelegge, Kym F KF Faull, H Ronald HR Kaback, Shimon S Schuldiner
EmrE is a small multidrug transporter in Escherichia coli that extrudes various positively charged drugs across the plasma membrane in exchange with protons, thereby rendering cells resistant to these...Read More
Rachel R Auzély-Velty, Marguerite M Rinaudo
A new route to starch derivatives bearing hydrolyzable cationic groups was developed. This was based on reacting starch compounds with betaine derivatives in the presence of diisopropylcarbodiimide an...Read More
Derek C DC Cole, Joseph R JR Stock, Jo Anne JA Kappel
A method has been developed for the oxidation of sulfides to sulfoxides on polystyrene resin. The polystyrene bound sulfoxide may be used in Swern oxidation reactions, and the used reagent may be rege...Read More
P J PJ Weber, J E JE Bader, G G Folkers, A G AG Beck-Sickinger
A new method has been developed to synthesize fluorescein labeled peptides, compounds of increasing importance in bioorganic chemistry, cell biology, pharmacology, drug targeting and medicinal chemist...Read More
B B BB Hayes, P C PC Gerber, S S SS Griffey, B J BJ Meade
Dicyclohexylcarbodiimide (DCC) and diisopropylcarbodiimide (DIC) are two commonly used coupling reagents in protein synthesis resulting in exposure of individuals in chemical and pharmaceutical indust...Read More
J J Eichler, R A RA Houghten, M M Lebl
Solid-phase synthesis of peptides was carried out using only the volume of the solvent included in the swollen solid-phase resin heads (inclusion volume synthesis). This approach enables (i) the use o...Read More
J J Izdebski, D D Kunce
A competitive reaction of activated Boc-Ala-OH and Boc-Phe-OH with H-Leu-resin has been developed for assessing the relative efficiencies of different carbodiimides. This allowed a comparison of the e...Read More
N R NR Shenoy, J M JM Bailey, J E JE Shively
We have developed a method for the covalent immobilization of peptides, for the purpose of C-terminal sequencing, to a novel solid support, carboxylic acid-modified polyethylene (PE-COOH) film. The pe...Read More
Diisopropylcarbodiimide is used as a reagent for peptide syntheses and as a chemical intermediate. The National Cancer Institute nominated diisopropylcarbodiimide for study as a representative chemica...Read More
Qiu Dai, James G Worden, Jonathan Trullinger, Qun Huo
Gold nanoparticles with a single carboxylic acid group on the surface were prepared from a solid phase place exchange reaction and then coupled to polylysine using an in situ activation agent, diisopr...Read More
K L KL Witt, R R RR Tice, M D MD Shelby, R S RS Chhabra, E E Zeiger
The induction of micronucleated erythrocytes by diisopropylcarbodiimide (DIC) and dicyclohexylcarbodiimide (DCC) was investigated as part of a U.S. National Toxicology Program (NTP) evaluation of the ...Read More
J J Izdebski, M M Pachulska, A A Or?owska
N-Cyclohexyl-N'-isopropylcarbodiimide was prepared and used for peptide couplings by various procedures. Reaction between Z-Val and Gly-OEt was used for yield studies and determination of the ext...Read More