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二苯基二硒

产品编号 D106407 | CAS号 1666-13-3 | Aladdin
Diphenyl diselenide
96%
组合的产品项目
货号 规格 库存 价格 数量
D106407-100g 96% 上海(1)
北方(预计3-5个工作日)
 
D106407-25g 96% 上海(预计3-7周)
北方(预计3-7周)
 
D106407-5g 96% 上海(>10)
北方(预计3-5个工作日)
 
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属性

熔点 60-63°C
沸点 202°C/11mmHg
溶解性 溶于热乙醇、乙醚、二甲苯。

描述

产品介绍 溶于热醇、醚和二甲苯。不溶于水。
别名 二苯基二硒醚,二硒二苯;二苯联硒;Phenyl diselenide
应用 用于合成烯丙基醇、烯丙基醚、乙酸酯和α,β-不饱和羰基化合物。
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标识符号 GHS06 GHS06, GHS08 GHS08, GHS09 GHS09
信号词 Danger
风险声明 (欧洲) 23/25,33,50/53
安全声明(欧洲) 20/21,28,45,60,61
警示性声明 P261,P273,P301+P310,P311,P501
危害码(欧洲) T,N
危害声明 H301,H331,H373,H410
个人防护设备 Eyeshields,Faceshields,Gloves,type P2 (EN 143) respirator cartridges
RTECS JM9152500
WGK德国 3
是否危化品 一般危险品
UN代码 3283
参考文献
Marina Prigol, Cristina W Nogueira, Gilson Zeni, Maria Rosário Bronze, Luís Constantino
The objective of the present study was to evaluate the physicochemical and biochemical profiling of diphenyl diselenide (PhSe)(2), a selenoorganic compound with biological activity. Experimental proto...Read More
Waseem W Hassan, Joao Batista Teixeira JB Rocha
Diphenyl diselenide has shown interesting biological activities in various free-radical-induced damage models and can be considered as a potential candidate drug against oxidative stress. Apart from i...Read More
Juliana Trevisan da Rocha, Tuane Bazanella Sampaio, José S Santos Neto, Cristina Wayne Nogueira, Gilson Zeni
This study investigated the effects of co-administration of diphenyl diselenide [(PhSe)(2)] and 17β-estradiol (E(2)) on spatial reference, recognition, and working memories in ovariectomized (OVX) fe...Read More
Marina Prigol, Cristina W Nogueira, Gilson Zeni, Maria Rosário Bronze, Luís Constantino
In spite of an extensive literature reporting pharmacological properties of diphenyl diselenide, (PhSe)(2), little is known about its metabolism. The aim of this study was to identify possible metabol...Read More
Mohammad Ibrahim, Waseem Hassan, Daiane Francine Meinerz, Matheus Dos Santos, Claudia V Klimaczewski, Anna M Deobald, Maricilia S Costa, Cristina W Nogueira, Nilda B V Barbosa, Joao B T Rocha
Diorganoyl dichalcogenide compouds can have antioxidant activity in different in vitro and in vivo models. Here, we have compared the potential antioxidant activity of 1-dinaphthyl diselenide (1-NapSe...Read More
Abhijit Sau, Anup Kumar Misra
Reaction of glycal derivatives with alcohols or glycosyl acceptors in the presence of N-bromosuccinimide (NBS) and diphenyldiselenide resulted in the formation of alkyl 2-deoxy-2-phenylselenyl glycosi...Read More
Mayara L de Freitas, Andreia R H da Silva, Silvane S Roman, Ricardo Brand?o
The effects of 4,4'-dichloro-diphenyl diselenide (ClPhSe)(2) on the toxicity induced by mercuric chloride (HgCl(2)) were investigated and compared with diphenyl diselenide (PhSe)(2). Mice receive...Read More
César A Brüning, Marina Prigol, Cristiane Luchese, Cristiano R Jesse, Marta M M F Duarte, Silvane S Roman, Cristina W Nogueira
Cerebrovascular diseases, including ischemic stroke, are associated with high mortality worldwide. Oxidative stress and inflammation are important pathophysiological mechanisms involved in post-ischem...Read More
Cristiane Luchese, Marina Prigol, Marta M M F Duarte, Cristina W Nogueira
We reported the anti-inflammatory action of diphenyl diselenide [(PhSe)(2)] in an acute inflammation model induced by carrageenan.Male adult Swiss mice.Mice were treated with (PhSe)(2) (50?mg/kg) or v...Read More
Marina Prigol, César Augusto Brüning, Franciele Martini, Cristina W Nogueira
The purpose of this study was to provide data about in vivo tissue distribution and excretion of diphenyl diselenide ((PhSe)(2)) in rats and mice through determination of selenium levels in different ...Read More
Fernando F Dobrachinski, Luiza Lena LL Bastos, Jessika Cristina JC Bridi, Cristiane Lenz Dalla CL Corte, Daiana Silva DS de ávila, Jo?o Batista Teixeira JB da Rocha, Félix Alexandre Antunes FA Soares
Excessive formation of reactive oxygen species (ROS) and disruption of glutamate uptake have been hypothesized as key mechanisms contributing to quinolinic acid (QA)-induced toxicity. Thus, here we in...Read More
Charlene Cavalheiro de Menezes, Jossiele Leitemperger, Adriana Santi, Thais Lópes, Cátia Aline Veiverberg, Sandra Peixoto, Martha Bohrer Adaime, Renato Zanella, Nilda Berenice Vargas Barbosa, Vania Lucia Loro
The occurrence of pollutants in the aquatic environment can produce severe toxic effects on non-target organisms, including fish. These sources of contamination are numerous and include herbicides, wh...Read More
Carmine Inês CI Acker, Ana Cristina Guerra AC Souza, Maurício Portella MP Dos Santos, Cinthia Melazzo CM Mazzanti, Cristina Wayne CW Nogueira
In this study, we investigated the effect of diphenyl diselenide [(PhSe)(2)] on chlorpyrifos (CPF)-induced hepatic and hematologic toxicity in rats....Read More
César Augusto Brüning, Marina Prigol, Cristiane Luchese, Simone Pinton, Cristina Wayne Nogueira
Bipolar disorder (BD) is a common and severe mood disorder associated with higher rates of suicide and disability. Ouabain, a Na(+)/K(+)-ATPase inhibitor, induces behavioral changes in rats and has be...Read More
Juliana Trevisan da Rocha, Bibiana Mozzaquatro Gai, Simone Pinton, Tuane Bazanella Sampaio, Cristina Wayne Nogueira, Gilson Zeni
The transition to menopause is associated with an increased risk of depressed mood.This study was conducted to investigate whether diphenyl diselenide [(PhSe)?] treatment could reduce the effects of p...Read More
Edovando J F EJ da Rosa, Michele Hinerasky MH da Silva, Nelson Rodrigues NR Carvalho, Jessika Cristina JC Bridi, Jo?o Batista JB da Rocha, Sara S Carbajo-Pescador, Jose Luiz JL Mauriz, Javier J González-Gallego, Félix Alexandre Antunes FA Soares
In this study, the authors evaluated the ability of diphenyl diselenide (PhSe)(2) to reverse acute hepatic failure induced by acetaminophen (APAP) in mice. The animals received an APAP dose of 600 mg/...Read More
Erico Silva ES Loreto, Sydney Hartz SH Alves, Janio Morais JM Santurio, Cristina Wayne CW Nogueira, Gilson G Zeni
This study evaluated the in vitro activity of diphenyl diselenide against 19 Pythium insidiosum isolates and the in vivo therapeutic response of rabbits with experimentally induced pythiosis. In vitro...Read More
Natalí L NL Chanaday, Andreza F AF de Bem, German A GA Roth
Experimental autoimmune encephalomyelitis (EAE) is a T cell-mediated inflammatory and demyelinating disease of the central nervous system with clinical and pathological similarities with multiple scle...Read More
D F DF Meinerz, M T MT de Paula, B B Comparsi, M U MU Silva, A E AE Schmitz, H C HC Braga, P S PS Taube, A L AL Braga, J B T JB Rocha, A L AL Dafre, M M Farina, J L JL Franco, T T Posser
We evaluated the potential neuroprotective effect of 1-100 μM of four organoselenium compounds: diphenyl diselenide, 3'3-ditri-fluoromethyldiphenyl diselenide, p-methoxy-diphenyl diselenide, and...Read More
Glaecir Roseni Mundstock GR Dias, Francielli Araújo FA Vieira, Fernando F Dobrachinski, Jéssika Cristina JC Bridi, Rodrigo de Souza Rde S Balk, Félix Antunes FA Soares, Cristina Wayne CW Nogueira, Nilda Berenice de Vargas NB Barbosa
Cognitive deficits have been observed in different animal models of adult-onset hypothyroidism. Thus, this study was delineated to evaluate whether diphenyl diselenide, an organoselenium compound with...Read More
Claire M CM Weekley, Jade B JB Aitken, Ian F IF Musgrave, Hugh H HH Harris
The selenoamino acids methylselenocysteine (MeSeCys) and selenomethionine (SeMet) have disparate efficacies as anticancer agents. Herein, we use X-ray absorption spectroscopy to determine the chemical...Read More
Lucía L LL Rupil, Andreza F AF de Bem, German A GA Roth
Diphenyl diselenide (PhSe)(2), a simple organoselenium compound, possesses interesting pharmacological properties that are under extensive research. As macrophages respond to microenvironmental stimul...Read More
Juliana T JT da Rocha, Simone S Pinton, Alexandre A Mazzanti, Cinthia M CM Mazzanti, Diego V DV Beckemann, Cristina W CW Nogueira, Gilson G Zeni
Ovarian hormone loss contributes to cognitive decline in postmenopausal women. Studies have demonstrated a positive role of the level of the element selenium in cognitive performance. The present stud...Read More
Cristiane L CL Dalla Corte, Luíza L LL Bastos, Fernando F Dobrachinski, Jo?o B T JB Rocha, Félix A A FA Soares
This study was designed to investigate the protective effects of the combination of guanosine and 2 organoselenium compounds (ebselen and diphenyl diselenide) against glutamate-induced oxidative stres...Read More
Michele Hinerasky MH da Silva, Edovando José Flores EJ da Rosa, Nélson Rodrigues NR de Carvalho, Fernando F Dobrachinski, Jo?o Batista Teixeira JB da Rocha, Jose L JL Mauriz, Javier J González-Gallego, Félix Alexandre Antunes FA Soares
Organoselenium compounds exhibit antioxidant activity, as well as a variety of biological activities, with potential pharmacological and therapeutic applications. The aim of this study was to investig...Read More