|别名||N，N-二甲基甲酰胺 ;二甲基甲酰胺,甲酰二甲胺,N-甲酰二甲胺,二甲替甲酰胺,N.N-二甲基甲酰胺 ;Fomryldimethylamine Form-ditmtehylamide DMF DMFA|
|标识符号||GHS02, GHS07, GHS08|
|个人防护设备||Eyeshields,Faceshields,full-face respirator (US),Gloves,multi-purpose combination respirator cartridge (US),type ABEK (EN14387) respirator filter|
A method was developed for the quantitative analysis of catechol and 4-methylcatechol in human urine. [U-14C]Catechol was used as in internal standard. Urine was treated with beta-glucuronidase and su...Read More
Rapid and efficient synthesis of nucleoside polyphosphates and their conjugates using sulfonyl imidazolium salts.
This unit describes a method for preparing nucleoside polyphosphates and their conjugates such as nucleoside triphosphates, symmetrical and unsymmetrical dinucleoside polyphosphates and sugar nucleoti...Read More
Drug-induced liver injury is a major issue of concern and has led to the withdrawal of a significant number of marketed drugs. An understanding of structure-activity relationships (SARs) of chemicals ...Read More
N,N-Dimethylformamide (DMF) has been widely used in industries because of its extensive miscibility with water and solvents. Its health effects include hepatotoxicity and male reproductoxicity, possib...Read More
New tetradentate Schiff bases of 2,2-dimethyl-1,3-diaminopropane and acetylacetone derivatives and their vanadyl complexes.
A series of new VO(IV) complexes with two new tetradentate Schiff base of 4,4'-(2,2-dimethylpropane-1,3-diyl)-bis(azan-1-yl-1-yldene)dipent-2-en-2-ol) [H(2)L(1)] and 3,3'-(2,2-dimethylpropan...Read More
New charge transfer molecular complex adducts of picric acid (C6H3N3O7) with triethylamine (C6H15N) and dimethylformamide (HCON(CH3)2) were synthesized successfully for the first time. Chemical compos...Read More
Antiplasmodial and leishmanicidal activities of 2-cyano-3-(4-phenylpiperazine-1-carboxamido) quinoxaline 1,4-dioxide derivatives.
Malaria and leishmaniasis are two of the World's most important tropical parasitic diseases. Thirteen new 2-cyano-3-(4-phenylpiperazine-1-carboxamido) quinoxaline 1,4-dioxide derivatives (CPCQs) ...Read More
Glycerol nucleic acid (GNA) has an acyclic phosphoglycerol backbone repeat-unit, but forms stable duplexes based on Watson-Crick base-pairing. Because of its structural simplicity, GNA is of particula...Read More
Polyphosphates and pyrophosphates of hexopyranoses as allosteric effectors of human hemoglobin: synthesis, molecular recognition, and effect on oxygen release.
Polyphosphorylated and perphosphorylated hexopyranose monosaccharides and disaccharides were synthesized from parent or partially protected carbohydrates as potential allosteric effectors of hemoglobi...Read More
A series of new fluorinated coumarins and 1-aza coumarins have been synthesized and the presence of fluorine in these molecules and its effect on their anti-microbial, anti-inflammatory and analgesic ...Read More
Microwave assisted synthesis of 2,2'-arylene-substituted bis(4H-3,1-benzoxazin-4-one) derivatives using the complex cyanuric chloride/N,N-dimethylformamide.
A new and efficient method has been designed to prepare 2,2'-arylene-substituted bis(4H-3,1-benzoxazin-4-one) derivatives by using the mixture of cyanuric chloride and N,N-dimethylformamide in a ...Read More
Measurement of urinary excretion of 5-hydroxymethyluracil in human by GC/NICI/MS: - Correlation with cigarette smoking, urinary TBARS and etheno DNA adduct
5-Hydroxymethyluracil (5-HMU) is derived from radiation in addition to endogenous oxidative DNA damage and it is one of the most abundant DNA adducts. Human 5-HMU-DNA-glycosylase has been shown to rep...Read More
We sought to test whether tetrahydrobiopterin (BH4) supplementation improves nitric oxide (NO) bioactivity in smokers....Read More
Quantification of urinary o,o'-dityrosine, a biomarker for oxidative damage to proteins, by high performance liquid chromatography with triple quadrupole tandem mass spectrometry. A comparison with ion-trap tandem mass spectrometry.
We recently described an isotope dilution reversed-phase liquid chromatography-atmospheric pressure chemical ionization-ion-trap-tandem mass spectrometry (HPLC-APCI-MS/MS) method for the quantitative ...Read More
Simultaneous analysis of nicotine, nicotine metabolites, and tobacco alkaloids in serum or urine by tandem mass spectrometry, with clinically relevant metabolic profiles.
Assessment of nicotine metabolism and disposition has become an integral part of nicotine dependency treatment programs. Serum nicotine concentrations or urine cotinine concentrations can be used to g...Read More
Smoking increases the risk of several chronic diseases associated with elevated oxidative stress status. Almonds are a good source of antioxidant nutrients and may diminish smoking-related biomarkers ...Read More
Determination of nicotine and four metabolites in the serum of smokers by high-performance liquid chromatography with ultraviolet detection.
A simple and reliable reversed-phase high-performance liquid chromatographic method with ultraviolet detection is described for the quantitation of nicotine and its metabolites cotinine, trans-3'...Read More
A single-step extraction method for the determination of nicotine and cotinine in Jordanian smokers' blood and urine samples by RP-HPLC and GC-MS.
A simple, rapid, reliable, and low cost one-step extraction method is developed and validated for the determination of nicotine and cotinine in human plasma and urine in smokers using reversed-phase h...Read More
A simple, rapid and sensitive liquid chromatography/mass spectrometry (LC/MS) method has been utilized for the quantitative determination of nicotine and its major metabolite cotinine (COT) in human c...Read More
Simultaneous determination of mercapturic acids derived from ethylene oxide (HEMA), propylene oxide (2-HPMA), acrolein (3-HPMA), acrylamide (AAMA) and N,N-dimethylformamide (AMCC) in human urine using liquid chromatography/tandem mass spectrometry.
Mercapturic acids are highly important and specific biomarkers of exposure to carcinogenic substances in occupational and environmental medicine. We have developed and validated a reliable, specific a...Read More
Benzylcyanide and 4-nitrobenzylcyanide condensed with triethyl orthoformate and piperidine or morpholine to yield 2-aryl-2-piperidinyl or 2-morpholinylacrylonitriles. These coupled with aromatic diazo...Read More
Highly efficient vinylaromatics generation via iron-catalyzed sp3 C-H bond functionalization CDC reaction: a novel approach to preparing substituted benzo[α]phenazines.
An iron-catalyzed benzylic vinylation was developed to transfer the carbon atom in the N,N-dimethyl moiety of N,N-dimethylacetamide (or N,N-dimethylformamide) to 2-methyl azaarenes to generate 2-vinyl...Read More
Synthesis of Bis-Acyclonucleoside Analogues Bearing Benzothienyl-1,2,4-Triazol-3-Yl-Disulfide under Conventional and Microwave Methods.
The oxidation of 5-(3-chlorobenzo[b]thien-2-yl)-4H-1,2,4-triazole-3-thiol (1) with a solution of iodine and potassium iodide at room temperature afforded [5-(3-chlorobenzo[b]thien-2-yl)-4H-1,2,4-triaz...Read More
For food industry production processes and other uses, a mold that produces high levels of feruloyl esterase was obtained from laboratory mold collections and other sources. It was Aspergillus awanmor...Read More
Anionic ring-opening polymerization of ethylene oxide in DMF with cyclodextrin derivatives as new initiators.
Anionic polymerization initiated by cyclodextrins suffers from a poor solubility of those derivatives in standard polymerization solvents. The possibility to perform ethylene oxide polymerization init...Read More
Large-scale 13C-flux analysis reveals distinct transcriptional control of respiratory and fermentative metabolism in Escherichia coli
Despite our increasing topological knowledge on regulation networks in model bacteria, it is largely unknown which of the many co-occurring regulatory events actually control metabolic function and th...Read More
Implications of apurinic/apyrimidinic endonuclease in reactive oxygen signaling response after cisplatin treatment of dorsal root ganglion neurons.
Peripheral neuropathy is one of the major side effects of the anticancer drug cisplatin. Although previous work suggests that this neuropathy correlates with formation of DNA adducts in sensory neuron...Read More
The conformationally coupled mechanism by which ATP is utilized by yeast Hsp90 is now well characterized. In contrast, ATP utilization by human Hsp90s is less well studied, and appears to operate diff...Read More
Shwachman-Diamond syndrome neutrophils have altered chemoattractant-induced F-actin polymerization and polarization characteristics.
Shwachman-Diamond syndrome is a hereditary disorder characterized by pancreatic insufficiency and bone marrow failure. Most Shwachman-Diamond syndrome patients have mutations in the SBDS gene located ...Read More
We're sorry this abstract is currently not available....Read More
Metal-independent decomposition of hydroperoxides by halogenated quinones: detection and identification of a quinone ketoxy radical.
We have shown recently that halogenated quinones could enhance the decomposition of hydroperoxides and formation of alkoxyl/hydroxyl radicals through a metal-independent mechanism. However, neither th...Read More
X-ray diffraction and infrared spectroscopy of N,N-dimethylformamide and dimethyl sulfoxide solvatomorphs of betulonic acid.
X-ray diffraction and infrared spectroscopy measurements for the N,N-dimethylformamide (DMF) and dimethyl sulfoxide (DMSO) solvatomorphs of betulonic acid (BA) were investigated. BA [3-oxolup-20(29)-e...Read More
Synthesis, spectroscopy, magnetic and redox behaviors of copper(II) complexes with tert-butylated salen type ligands bearing bis(4-aminophenyl)ethane and bis(4-aminophenyl)amide backbones.
New salen type ligands, N,N'-bis(X-3-tert-butylsalicylidene)-4,4'-ethylenedianiline [(X=H (1), 5-tert-butyl (2)] and N,N'-bis(X-3-tert-butylsalicylidene)-4,4'-amidedianiline [X=H (...Read More
Mass spectrometric evaluation of neuropeptidomic profiles upon heat stabilization treatment of neuroendocrine tissues in crustaceans.
Tissue heat stabilization is a vital component in successful mammalian neuropeptidomic studies. Heat stabilization using focused microwave irradiation, conventional microwave irradiation, boiling, and...Read More
One-step dispersion of cellulose nanofibers by mechanochemical esterification in an organic solvent.
Got a crush: Native cellulose can be dispersed as nanofibers in organic solvents by ball milling with esterification agents. Milling with hexanoyl chloride/DMF gives hexanoyl-coated nanofibers dispers...Read More
Among the currently available positron emitters suitable for Positron Emission Tomography (PET), (124)I has the longest physical half-life (4.2 days). The long half-life and well-investigated behavior...Read More
Regioselectivity in Sonogashira synthesis of 6-(4-nitrobenzyl)-2-phenylthiazolo[3,2-b]1,2,4-triazole: a quantum chemistry study.
In the present research, the experimentally observed regioselectivity in Sonogashira synthesis of 6-(4-nitrobenzyl)-2-phenylthiazolo[3,2-b]1,2,4triazole has been modeled by means of density functional...Read More
Effect of acute exposure of N,N-dimethylformamide, an industrial solvent on lipid peroxidation and antioxidants in liver and kidney of rats.
N,N-Dimethylformamide (DMF), an industrial solvent widely used throughout the world is a known toxic compound. Here, we studied the effects of acute exposure of DMF on liver and kidney in rats. Rats w...Read More
Studies on the self-assembly of metal nanoparticles (NPs) in the presence of ions are motivated by the biosensing applications of NP clusters and the capability to control the morphology of clusters o...Read More
Often used as a common solvent for chemical reations and utilized widely in industry as a reagent, N,N-dimethylformamide (DMF) has played an important role in organic synthesis for a long time. Numero...Read More
A reliable method to decide whether two polymers A and B are miscible or incompatible would be very helpful in many ways. In this contribution we demonstrate why traditional procedures cannot work. We...Read More
A novel thin capsule motor has been described in this report. It utilizes the Marangoni effect for the solid capsule to run at a water-oil interlayer, which has not been reported previously. Intrinsic...Read More
Absorption spectra of PTCDI (3,4,9,10-perylene-tetracarboxylic-diimide) have been investigated in chloroform, N,N'-dimethylformamide (DMF) and dimethylsulfoxide (DMSO). While no signature of asse...Read More
An ester terminated dihydroimidazonaphthalimide as multi-functional logic device is presented. Due to the optical changes as a function of pH this simple molecule is able to act as a molecular pH metr...Read More
Synthesis and investigation on photophysical and photochemical properties of 7-oxy-3-methyl-4-phenylcoumarin bearing zinc phthalocyanines.
The synthesis of peripherally and non-peripherally tetrakis-(7-oxy-3-methyl-4-phenylcoumarin) and peripherally octakis-[tetrachlorotetra-(7-oxy-3-methyl-4-phenyl coumarin)] substituted zinc(II) phthal...Read More
Syntheses, crystal structure and luminescent properties of cadmium complexes based on 2,6-bis(1-phenylbenzimidazol-2-yl)pyridine.
Two cadmium complexes, Cd(bpbp)Cl(2) (complex 1) and [Cd(bpbp)(2)](ClO(4))(2) (complex 2), based on 2,6-bis(1-phenylbenzimidazol-2-yl)pyridine (bpbp), were synthesized and characterized by X-ray singl...Read More
A second-order nonlinear optical material with a hydrated homochiral helix obtained via spontaneous symmetric breaking crystallization from an achiral ligand.
A unique supramolecular helix assisted by solvent molecules (water and DMF) is obtained from an achiral flexible V-shaped ligand, and spontaneous symmetry breaking occurs in crystallization. Notably, ...Read More
The Schiff base derivatives of benzopyran-4-one are characterized by imine groups which have biological activities such as antimicrobial, antifungal and antitumoral. The aim of this study was therefor...Read More
Curcumin, a yellow pigment and the active component of turmeric, has been shown to protect against carcinogenesis and prevent tumor development in several types of cancer. However, its low bioavailabi...Read More